The Nerve Growth Factor-Responsive PC12 Cell Line Does Not Express the Myc Dimerization Partner Max

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

Induction of apoptosis in fibroblasts by c-myc protein

1992 • 2,977 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

Current Protocols in Molecular Biology

1989 • 1,916 citations

Max: A Helix-Loop-Helix Zipper Protein That Forms a Sequence-Specific DNA-Binding Complex with Myc

1991 • 1,650 citations

Sequence-Specific DNA Binding by the c-Myc Protein

1990 • 893 citations

Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells.

1985 • 888 citations

Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis.

1991 • 861 citations

Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites

1993 • 786 citations

Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain

1993 • 723 citations

Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity

1993 • 711 citations

Role for c-myc in Activation-Induced Apoptotic Cell Death in T Cell Hybridomas

1992 • 705 citations

A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1

1987 • 696 citations

Methylation-Sensitive Sequence-Specific DNA Binding by the c-Myc Basic Region

1991 • 596 citations

Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation

1991 • 576 citations

Cell Growth & Differentiation

1992 • 558 citations

Oncogenic activity of the c-Myc protein requires dimerization with Max

1993 • 543 citations

Constitutive c-myc oncogene expression blocks mouse erythroleukaemia cell differentiation but not commitment

1986 • 536 citations

A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice.

1993 • 536 citations

Myc and Max proteins possess distinct transcriptional activities

1992 • 478 citations

An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation.

1988 • 476 citations

The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice

1986 • 441 citations

Myc and Max associate in vivo.

1992 • 428 citations

The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max.

1993 • 392 citations

Binding of myc proteins to canonical and noncanonical DNA sequences.

1993 • 375 citations

Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activity.

1991 • 359 citations

Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms

1991 • 337 citations

Amino-terminal domains of c-myc and N-myc proteins mediate binding to the retinoblastoma gene product

1991 • 326 citations

The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB.

1993 • 317 citations

Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene.

1992 • 314 citations

c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II.

1994 • 313 citations

A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation.

1993 • 294 citations

Max: functional domains and interaction with c-Myc.

1992 • 280 citations

Inhibition of Transcriptional Regulator Yin-Yang-1 by Association with c-Myc

1993 • 273 citations

A system for characterizing cellular and molecular events in programmed neuronal cell death

1993 • 267 citations

Repression of cyclin D1: a novel function of MYC.

1994 • 250 citations

Nerve growth factor regulates tyrosine hydroxylase gene transcription through a nucleoprotein complex that contains c-Fos.

1990 • 247 citations

Direct role for Myc in transcription initiation mediated by interactions with TFII-I

1993 • 246 citations

Binding and Suppression of the Myc Transcriptional Activation Domain by p107

1994 • 242 citations

IL-2 and EGF receptors stimulate the hematopoietic cell cycle via different signaling pathways: Demonstration of a novel role for c-myc

1992 • 242 citations

Report of the committee on structural chromosome changes in neoplasia

1988 • 230 citations

A Specific Amino Acid Binding Site Composed of RNA

1988 • 203 citations

Involvement of the 'leucine zipper' region in the oligomerization and transforming activity of human c-myc protein

1989 • 198 citations

Expression of mad, mxi1, max and c-myc during induced differentiation of hematopoietic cells: opposite regulation of mad and c-myc.

1994 • 159 citations

The N-Myc oncoprotein is associated in vivo with the phosphoprotein Max(p20/22) in human neuroblastoma cells.

1991 • 148 citations

TATA-binding protein and the retinoblastoma gene product bind to overlapping epitopes on c-Myc and adenovirus E1A protein.

1993 • 146 citations

pGSTag--a versatile bacterial expression plasmid for enzymatic labeling of recombinant proteins.

1992 • 136 citations

Sequence-specific DNA binding by Myc proteins.

1991 • 130 citations

Myc family oncoproteins function through a common pathway to transform normal cells in culture: cross-interference by Max and trans-acting dominant mutants.

1992 • 129 citations

Bcl-2 affects survival but not neuronal differentiation of PC12 cells

1993 • 129 citations

Sequence-Specific Transcriptional Activation by Myc and Repression by Max

1993 • 124 citations

Specific inhibition of c-myc protein biosynthesis using an antisense synthetic deoxy-oligonucleotide in human T lymphocytes.

1988 • 119 citations

Report of the committee on structural chromosome changes in neoplasia

1989 • 112 citations

Definition of the activities and properties of c-myc required to inhibit cell differentiation.

1990 • 104 citations

Nerve growth factor has both mitogenic and antimitogenic activity

1982 • 103 citations

max encodes a sequence-specific DNA-binding protein and is not regulated by serum growth factors.

1992 • 92 citations

Repression of Cyclin D1: a Novel Function of MYC

1994 • 84 citations

Intracellular Association of the Protein Product of the c-myc Oncogene with the TATA-Binding Protein

1994 • 78 citations

myc and E1A oncogenes alter the responses of PC12 cells to nerve growth factor and block differentiation.

1987 • 66 citations

Mutational analysis of Max: role of basic, helix-loop-helix/leucine zipper domains in DNA binding, dimerization and regulation of Myc-mediated transcriptional activation.

1992 • 53 citations

Adenovirus 5 E1A proteins disrupt the neuronal phenotype and growth factor responsiveness of PC12 cells by a conserved region 1-dependent mechanism.

1993 • 48 citations

Expression, regulation, and chromosomal localization of the Max gene.

1992 • 47 citations

c-Myc Does Not Require Max for Transcriptional Activity in PC-12 Cells

1994 • 28 citations

Transfected wild-type and mutant max regulate cell growth and differentiation of murine erythroleukemia cells.

1993 • 18 citations

Mapping of MAX to human chromosome 14 and mouse chromosome 12 by in situ hybridization.

1992 • 16 citations

Structural analysis of the chicken max gene.

1994 • 16 citations

New Miocene polarity scale

1974 • 1 citations