The cell membrane and the struggle for life of lactic acid bacteria

Inactivation of Antibiotics and the Dissemination of Resistance Genes

1994 • 1,766 citations

BACTERIAL HEAVY METAL RESISTANCE: New Surprises

1996 • 1,263 citations

The Complete Genome Sequence of the Lactic Acid Bacterium Lactococcus lactis ssp. lactis IL1403

2001 • 1,025 citations

Occurrence and formation of biologically active amines in foods

1990 • 890 citations

The Complete Genome Sequence of the Lactic Acid Bacterium Lactococcus lactis ssp. lactis IL1403

2001 • 867 citations

Carbohydrate metabolism in lactic acid bacteria

1983 • 866 citations

Molecular Properties of Bacterial Multidrug Transporters

2000 • 771 citations

Synergy in a medicinal plant: Antimicrobial action of berberine potentiated by 5′-methoxyhydnocarpin, a multidrug pump inhibitor

2000 • 724 citations

The proteotytic systems of lactic acid bacteria

1996 • 687 citations

Lactic Acid Bacteria

1993 • 672 citations

Resistance to Antibiotics Mediated by Target Alterations

1994 • 671 citations

GENETIC ANALYSIS OF THE MULTIDRUG TRANSPORTER

1995 • 469 citations

Cell compartmentalisation in planctomycetes: novel types of structural organisation for the bacterial cell

2001 • 362 citations

Multidrug resistance pumps in bacteria: variations on a theme

1994 • 314 citations

The physiology and biochemistry of the proteolytic system in lactic acid bacteria

1993 • 294 citations

Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDR1.

1996 • 275 citations

Proposal To Reclassify Leuconostoc oenos as Oenococcus oeni [corrig.] gen. nov., comb. nov.

1995 • 271 citations

The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism

2000 • 267 citations

Relation of growth of Streptococcus lactis and Streptococcus cremoris to amino acid transport

1988 • 254 citations

Regulation of compatible solute accumulation in bacteria

1998 • 251 citations

Generation of a proton motive force by histidine decarboxylation and electrogenic histidine/histamine antiport in Lactobacillus buchneri

1993 • 243 citations

The preferred stoichiometry of c subunits in the rotary motor sector of Escherichia coli ATP synthase is 10

2001 • 238 citations

Respiration Capacity of the Fermenting Bacterium Lactococcus lactis and Its Positive Effects on Growth and Survival

2001 • 234 citations

A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene

1998 • 234 citations

Arginine deiminase system and bacterial adaptation to acid environments

1987 • 207 citations

Bioenergetics and Solute Transport in Lactococci

1989 • 202 citations

Multidrug resistance in Lactococcus lactis: evidence for ATP-dependent drug extrusion from the inner leaflet of the cytoplasmic membrane.

1996 • 194 citations

Oligopeptides are the main source of nitrogen for Lactococcus lactis during growth in milk

1995 • 188 citations

Hop Resistance in the Beer Spoilage Bacterium Lactobacillus brevis Is Mediated by the ATP-Binding Cassette Multidrug Transporter HorA

2001 • 184 citations

Exchange of glutamate and gamma-aminobutyrate in a Lactobacillus strain

1997 • 183 citations

Osmoregulated ABC-transport system of Lactococcus lactis senses water stress via changes in the physical state of the membrane

2000 • 183 citations

On the osmotic signal and osmosensing mechanism of an ABC transport system for glycine betaine

2001 • 182 citations

Arginine metabolism in lactic streptococci

1982 • 177 citations

Arginine Catabolism by Microorganisms

1979 • 174 citations

Generation of an electrochemical proton gradient in Streptococcus cremoris by lactate efflux.

1980 • 171 citations

Regulation of arginine-ornithine exchange and the arginine deiminase pathway in Streptococcus lactis

1987 • 169 citations

Streptococcal cytoplasmic pH is regulated by changes in amount and activity of a proton-translocating ATPase.

1986 • 168 citations

Malolactic fermentation: electrogenic malate uptake and malate/lactate antiport generate metabolic energy

1991 • 165 citations

The ABC family of multidrug transporters in microorganisms

1998 • 162 citations

Comparative Study of Action of Cell Wall Proteinases from Various Strains of Streptococcus cremoris on Bovine α _s1 -, β-, and κ-Casein

1986 • 157 citations

Lactate efflux-induced electrical potential in membrane vesicles of Streptococcus cremoris.

1982 • 149 citations

The extracellular PI-type proteinase of Lactococcus lactis hydrolyzes beta-casein into more than one hundred different oligopeptides

1995 • 147 citations

Some roles of malic acid in the malolactic fermentation in wine making

1991 • 143 citations

Generation of an electrochemical proton gradient in bacteria by the excretion of metabolic end products

1979 • 139 citations

Regulation of solute transport in streptococci by external and internal pH values

1987 • 126 citations

Casein utilization by lactococci

1991 • 125 citations

The Lactococcal lmrP Gene Encodes a Proton Motive Force- dependent Drug Transporter

1995 • 119 citations

Bioenergetic consequences of lactose starvation for continuously cultured Streptococcus cremoris

1987 • 118 citations

The di- and tripeptide transport protein of Lactococcus lactis. A new type of bacterial peptide transporter

1994 • 114 citations

The role of transport processes in survival of lactic acid bacteria. Energy transduction and multidrug resistance.

1997 • 113 citations

Peptides and ATP binding cassette peptide transporters

2001 • 112 citations

Electrochemical proton gradient and lactate concentration gradient in Streptococcus cremoris cells grown in batch culture

1982 • 108 citations

Characteristics and osmoregulatory roles of uptake systems for proline and glycine betaine in Lactococcus lactis

1993 • 107 citations

In vivo regulation of glycolysis and characterization of sugar: phosphotransferase systems in Streptococcus lactis

1978 • 106 citations

Proton motive force-driven and ATP-dependent drug extrusion systems in multidrug-resistant Lactococcus lactis

1994 • 105 citations

Osmotic regulation of intracellular solute pools in Lactobacillus plantarum

1996 • 105 citations

Energetics and Mechanism of Drug Transport Mediated by the Lactococcal Multidrug Transporter LmrP

1996 • 104 citations

Energy recycling by lactate efflux in growing and nongrowing cells of Streptococcus cremoris

1985 • 102 citations

Transport of β-Casein-derived Peptides by the Oligopeptide Transport System Is a Crucial Step in the Proteolytic Pathway of Lactococcus lactis

1995 • 102 citations

Characterization of Plasmid Deoxyribonucleic Acid in Streptococcus lactis subsp. diacetylactis : Evidence for Plasmid-Linked Citrate Utilization

1979 • 101 citations

Proton motive force generation by citrolactic fermentation in Leuconostoc mesenteroides

1996 • 101 citations

Kinetic properties of a phosphate-bond-driven glutamate-glutamine transport system in Streptococcus lactis and Streptococcus cremoris

1987 • 98 citations

Multidrug transporters from bacteria to man: similarities in structure and function

1997 • 97 citations

Induction of cytochrome formation and stimulation of oxidative dissimilation by hemin inStreptococcus lactis andLeuconostoc mesenteroides

1970 • 96 citations

Hop-resistant Lactobacillus brevis contains a novel plasmid harboring a multidrug resistance-like gene

1997 • 96 citations

Regulation of the glutamate-glutamine transport system by intracellular pH in Streptococcus lactis

1987 • 96 citations

Exchange of Aspartate and Alanine

1996 • 94 citations

Mechanism of Citrate Metabolism in Lactococcus lactis : Resistance against Lactate Toxicity at Low pH

1999 • 91 citations

Lactic acid bacteria: starters for flavour

1987 • 90 citations

Lactose metabolism in Streptococcus lactis: phosphorylation of galactose and glucose moieties in vivo

1979 • 88 citations

Kinetics and Specificity of Peptide Uptake by the Oligopeptide Transport System of Lactococcus lactis

1998 • 88 citations

The efflux of a fluorescent probe is catalyzed by an ATP-driven extrusion system in Lactococcus lactis

1992 • 87 citations

Arginine transport in Streptococcus lactis is catalyzed by a cationic exchanger.

1987 • 82 citations

The Citrate Transport System of Lactococcus lactis subsp. lactis biovar diacetylactis Is Induced by Acid Stress

1998 • 82 citations

Tyrosine and Histidine Decarboxylase Activities of Pediococcus cerevisiae and Lactobacillus Species and the Production of Tyramine in Fermented Sausages

1976 • 81 citations

The Occurrence and Distribution of Amino-acid Decarboxylases within the Genus Lactobacillus

1953 • 80 citations

Di-tripeptides and oligopeptides are taken up via distinct transport mechanisms in Lactococcus lactis

1993 • 78 citations

Distribution of Cytochrome-like Respiration in Streptococci

1976 • 78 citations

Galactose transport systems in Streptococcus lactis

1980 • 77 citations

Comparison of cell wall proteinases from Lactococcus lactis subsp. cremoris AC1 and Lactococcus lactis subsp. lactis NCDO 763

1989 • 76 citations

Combinatorial peptide libraries reveal the ligand-binding mechanism of the oligopeptide receptor OppA of Lactococcus lactis

2000 • 75 citations

Nucleotide sequence and expression in Escherichia coli of the Lactococcus lactis citrate permease gene

1990 • 72 citations

Neutral amino acid transport by membrane vesicles of Streptococcus cremoris is subject to regulation by internal pH

1987 • 72 citations

The lactose transport protein is a cooperative dimer with two sugar translocation pathways

2001 • 72 citations

Control of glycolysis by glyceraldehyde-3-phosphate dehydrogenase in Streptococcus cremoris and Streptococcus lactis

1987 • 71 citations

Specificity of a cell wall proteinase fromStreptococcus lactisNCDO763 towards bovine β-casein

1986 • 71 citations

Obligatory coupling between proton entry and the synthesis of adenosine 5'-triphosphate in Streptococcus lactis

1977 • 69 citations

Glycine Betaine Transport in Lactococcus lactis Is Osmotically Regulated at the Level of Expression and Translocation Activity

2000 • 69 citations

The generation of metabolic energy by solute transport

1995 • 66 citations

The generation of metabolic energy by solute transport

1995 • 63 citations

Transport of branched-chain amino acids in membrane vesicles of Streptococcus cremoris

1987 • 62 citations

Uniport of Monoanionic L‐malate in Membrane Vesicles from Leuconostoc Oenos

1994 • 62 citations

Reconstruction of the proteolytic pathway for use of β‐casein by Lactococcus lactis

1998 • 62 citations

Survival of Streptococcus lactis in Starvation Conditions

1968 • 59 citations

Mechanism of energy coupling to entry and exit of neutral and branched chain amino acids in membrane vesicles of Streptococcus cremoris.

1987 • 58 citations

Lactose metabolism in Streptococcus lactis: studies with a mutant lacking glucokinase and mannose-phosphotransferase activities

1985 • 58 citations

The lactococcal secondary multidrug transporter LmrP confers resistance to lincosamides, macrolides, streptogramins and tetracyclines

2001 • 58 citations

Uniport of anionic citrate and proton consumption in citrate metabolism generates a proton motive force in Leuconostoc oenos

1994 • 57 citations

Mechanism of Osmotic Activation of the Quaternary Ammonium Compound Transporter (QacT) of Lactobacillus plantarum

1998 • 57 citations

Uptake and metabolism of sucrose by Streptococcus lactis

1981 • 57 citations

Escherichia coli adenylate cyclase complex: regulation by the proton electrochemical gradient.

1979 • 57 citations

Regulation of solute transport in streptococci by external and internal pH values.

1987 • 55 citations

The proteolytic pathway of Lactococcus lactis.

1995 • 54 citations

Energy transduction and solute transport in streptococci

1983 • 54 citations

Phosphate/hexose 6-phosphate antiport in Streptococcus lactis

1984 • 52 citations

A plasmid pRH45 of Lactobacillus brevis confers hop resistance.

1998 • 51 citations

The ecology of the streptococci

1982 • 49 citations

Modelling growth rates of Listeria innocua as a function of lactate concentration

1994 • 48 citations

Dependence of Streptococcus lactis phosphate transport on internal phosphate concentration and internal pH

1987 • 47 citations

Hemin Reconstitutes Proton Extrusion in an H ⁺ -ATPase-Negative Mutant of Lactococcus lactis

2001 • 46 citations

Reconstitution of ATP-dependent calcium transport from streptococci.

1986 • 44 citations

Specificity of hydrolysis of bovine kappa-casein by cell envelope-associated proteinases from Lactococcus lactis strains

1994 • 42 citations

Multidrug transport by ATP binding cassette transporters: a proposed two-cylinder engine mechanism

2001 • 41 citations

Increase of molar growth yield ofStreptococcus cremorisfor lactose as a consequence of lactate consumption byPseudomonas stutzeriin mixed culture

1980 • 39 citations

Mechanism and energetics of a citrate‐transport system of Klebsiella pneumoniae

1991 • 39 citations

Characterization of a citrate-negative mutant of Leuconostoc mesenteroides subsp. mesenteroides: metabolic and plasmidic properties

1991 • 38 citations

STUDIES ON PROTEINOGENOUS AMINES

1924 • 37 citations

Generation of metabolic energy by end-product efflux

1985 • 37 citations

Transport of basic amino acids by membrane vesicles of Lactococcus lactis

1989 • 36 citations

Genetic and functional characterization of dpp genes encoding a dipeptide transport system in Lactococcus lactis

2001 • 36 citations

STUDIES ON PROTEINOGENOUS AMINES

1924 • 36 citations

Can the excretion of metabolites by bacteria be manipulated?

1992 • 33 citations

AMINO ACID DECARBOXYLASES OF LACTIC ACID BACTERIA

1952 • 32 citations

Some roles of malic acid in the malolactic fermentation in wine making

1991 • 32 citations

Transport of glycine-betaine by Listeria monocytogenes

1994 • 31 citations

Structure-function analysis of multidrug transporters in Lactococcus lactis

1999 • 31 citations

Light-induced generation of a protonmotive force and Ca2+-transport in membrane vesicles of Streptococcus cremoris fused with bacteriorhodopsin proteoliposomes

1985 • 31 citations

The application of pH-sensitive fluorescent dyes in lactic acid bacteria reveals distinct extrusion systems for unmodified and conjugated dyes

1996 • 27 citations

Comparison of cell wall proteinases from Lactococcus lactis subsp. cremoris AC1 and Lactococcus lactis subsp. lactis NCDO 763

1989 • 24 citations

Action of a cell-envelope proteinase (CEPIII-type) from Lactococcus lactis subsp. cremoris AM1 on bovine κ-casein

1994 • 23 citations

An ecophysiological study of starter streptococci

1981 • 20 citations

The Contribution of Caseins to the Amino Acid Supply for Lactococcus lactis Depends on the Type of Cell Envelope Proteinase

1998 • 16 citations

The Effect of Haematin and Catalase on Streptococcus faecalis var. zymogenes Growing on Glycerol

1980 • 14 citations

Recent Advances in Biological Membrane Studies

1986 • 12 citations

The Autoproteolysis of Lactococcus lactis Lactocepin III Affects Its Specificity towards β-Casein

2000 • 11 citations

Generation of an electrochemical proton gradient in bacteria by the excretion of metabolic end products

1979 • 6 citations

Light Induced Generation of a Proton Motive Force and Ca++-Transport in Membrane Vesicles of Streptococcus Cremoris Fused with Bacteriorhodopsin Proteoliposomes

1985 • 4 citations