Caspase Recruitment Domain (CARD) as a Bi-functional Switch of Caspase Regulation and NF-κB Signals

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

2001 • 4,997 citations

Nod2, a Nod1/Apaf-1 Family Member That Is Restricted to Monocytes and Activates NF-κB

2001 • 1,331 citations

CARD15 mutations in Blau syndrome

2001 • 945 citations

Nod1, an Apaf-1-like Activator of Caspase-9 and Nuclear Factor-κB

1999 • 725 citations

An Induced Proximity Model for NF-κB Activation in the Nod1/RICK and RIP Signaling Pathways

2000 • 535 citations

ASC, a Novel 22-kDa Protein, Aggregates during Apoptosis of Human Promyelocytic Leukemia HL-60 Cells

1999 • 516 citations

Identification of Ipaf, a Human Caspase-1-activating Protein Related to Apaf-1

2001 • 439 citations

RIP2 Is a Novel NF-κB-activating and Cell Death-inducing Kinase

1998 • 425 citations

Human CARD4 Protein Is a Novel CED-4/Apaf-1 Cell Death Family Member That Activates NF-κB

1999 • 363 citations

ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases

1998 • 350 citations

CARD11 and CARD14 Are Novel Caspase Recruitment Domain (CARD)/Membrane-associated Guanylate Kinase (MAGUK) Family Members that Interact with BCL10 and Activate NF-κB

2001 • 328 citations

Interaction between Pyrin and the Apoptotic Speck Protein (ASC) Modulates ASC-induced Apoptosis

2001 • 284 citations

ICEBERG

2000 • 267 citations

RICK, a Novel Protein Kinase Containing a Caspase Recruitment Domain, Interacts with CLARP and Regulates CD95-mediated Apoptosis

1998 • 232 citations

CARD9 Is a Novel Caspase Recruitment Domain-containing Protein That Interacts With BCL10/CLAP and Activates NF-κB

2000 • 225 citations

A Novel Enhancer of the Apaf1 Apoptosome Involved in Cytochrome c-dependent Caspase Activation and Apoptosis

2001 • 183 citations

Regulation of IL-1β generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins

2001 • 182 citations

A Prosurvival Function for the p75 Receptor Death Domain Mediated via the Caspase Recruitment Domain Receptor-Interacting Protein 2

2001 • 165 citations

COP, a Caspase Recruitment Domain-containing Protein and Inhibitor of Caspase-1 Activation Processing

2001 • 163 citations

Molecular Cloning and Characterization of DEFCAP-L and -S, Two Isoforms of a Novel Member of the Mammalian Ced-4 Family of Apoptosis Proteins

2001 • 149 citations

CIPER, a Novel NF κB-activating Protein Containing a Caspase Recruitment Domain with Homology to Herpesvirus-2 Protein E10

1999 • 142 citations

CARD10 Is a Novel Caspase Recruitment Domain/Membrane-associated Guanylate Kinase Family Member That Interacts with BCL10 and Activates NF-κB

2001 • 140 citations

mE10, a Novel Caspase Recruitment Domain-containing Proapoptotic Molecule

1999 • 120 citations

TUCAN, an Antiapoptotic Caspase-associated Recruitment Domain Family Protein Overexpressed in Cancer

2001 • 117 citations

Human CARD12 Is a Novel CED4/Apaf-1 Family Member That Induces Apoptosis

2001 • 115 citations

The Apoptotic Regulatory Protein ARC (Apoptosis Repressor with Caspase Recruitment Domain) Prevents Oxidant Stress-mediated Cell Death by Preserving Mitochondrial Function

2001 • 111 citations

CARDINAL, a Novel Caspase Recruitment Domain Protein, Is an Inhibitor of Multiple NF-κB Activation Pathways

2001 • 111 citations

CLAP, a Novel Caspase Recruitment Domain-containing Protein in the Tumor Necrosis Factor Receptor Pathway, Regulates NF-κB Activation and Apoptosis

1999 • 111 citations

Equine Herpesvirus-2 E10 Gene Product, but Not Its Cellular Homologue, Activates NF-κB Transcription Factor and c-Jun N-terminal Kinase

1999 • 101 citations

CLAN, a Novel Human CED-4-like Gene

2001 • 72 citations

Bouchier-Hayes, L. et al. CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-B activation pathways. J. Biol. Chem. 276, 44069-44077

2001 • 14 citations