Increased Expression and Activity of RhoA Are Associated With Increased DNA Synthesis and Reduced p27 ^Kip1 Expression in the Vasculature of Hypertensive Rats

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

1997 • 2,847 citations

Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)

1996 • 2,843 citations

Role of the Ubiquitin-Proteasome Pathway in Regulating Abundance of the Cyclin-Dependent Kinase Inhibitor p27

1995 • 1,848 citations

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

1999 • 1,558 citations

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

2000 • 1,431 citations

Rho-associated Kinase Directly Induces Smooth Muscle Contraction through Myosin Light Chain Phosphorylation

1997 • 576 citations

Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1

1998 • 468 citations

Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction.

1992 • 458 citations

3-Hydroxy-3-methylglutaryl-CoA Reductase Inhibitors Attenuate Vascular Smooth Muscle Proliferation by Preventing Rho GTPase-induced Down-regulation of p27

1999 • 389 citations

The Role of Rho in G Protein-Coupled Receptor Signal Transduction

2000 • 345 citations

Nitric oxide inhibits angiotensin II-induced migration of rat aortic smooth muscle cell. Role of cyclic-nucleotides and angiotensin1 receptors.

1995 • 325 citations

Activation of RhoA by Lysophosphatidic Acid and Gα_12/13Subunits in Neuronal Cells: Induction of Neurite Retraction

1999 • 303 citations

Rho and Rho Kinase Mediate Thrombin-Stimulated Vascular Smooth Muscle Cell DNA Synthesis and Migration

1999 • 260 citations

Rho as a Mediator of G Protein-Coupled Receptor Signaling

1999 • 244 citations

Angiotensin II Activates RhoA in Cardiac Myocytes

1998 • 224 citations

Angiotensin II-induced proliferation of aortic myocytes in spontaneously hypertensive rats

1990 • 174 citations

Differential Translocation of Rho Family GTPases by Lysophosphatidic Acid, Endothelin-1, and Platelet-derived Growth Factor

1996 • 151 citations

Evidence That Rho-Kinase Activity Contributes to Cerebral Vascular Tone In Vivo and Is Enhanced During Chronic Hypertension

2001 • 116 citations

Sequestration of a G-protein βγ Subunit or ADP-ribosylation of Rho Can Inhibit Thrombin-induced Activation of Platelet Phosphoinositide 3-Kinases

1995 • 93 citations

Physical and Functional Interactions of Gαq with Rho and Its Exchange Factors

2001 • 93 citations

Augmented agonist-induced Ca(2+)-sensitization of coronary artery contraction in genetically hypertensive rats. Evidence for altered signal transduction in the coronary smooth muscle cells.

1994 • 71 citations

Involvement of botulinum C3-sensitive GTP-binding proteins in α1-adrenoceptor subtypes mediating Ca2+-sensitization

1995 • 39 citations

Migration of vascular smooth muscle cells is enhanced in cultures derived from spontaneously hypertensive rat

1997 • 29 citations

G-Protein-Coupled Receptors in Vascular Smooth Muscle Cells

1998 • 25 citations

Elevated vascular angiotensin converting enzyme mediates increased neointima formation after balloon injury in spontaneously hypertensive rats

1997 • 21 citations

Increased Ca2+ sensitivity of alpha 1-adrenoceptor-stimulated contraction in SHR caudal artery

1986 • 21 citations

Inositol Phosphate Formation and Contractile Responsem Linked to α1Adrenoceptor in Tail Artery and Aorta from Spontaneously Hypertensive and Wistar-Kyoto Rats

1993 • 20 citations

Stimulation of two vascular smooth muscle‐derived cell lines by angiotensin II: differential second messenger responses leading to mitogenesis

1995 • 17 citations

The Effects of Antihypertensive Agents on Atherosclerosis-Related Parameters of Human Aorta Intimal Cells

1998 • 13 citations

Abnormal proliferative response of the carotid artery of spontaneously hypertensive rats after angioplasty may be related to the depolarized state of its smooth muscle cells

2000 • 9 citations

Effect of hypertension on arterial structure and wound repair at the microvascular anastomosis site using stroke‐prone spontaneously hypertensive rats (SHRSP)

1993 • 8 citations

Translating Data on Antihypertensive Drugs Into Clinical Practice

1998 • 4 citations