Tumor Necrosis factor- and Expression of the Multidrug Resistance-Associated Genes LRP and MRP

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

1992 • 3,039 citations

CLINICAL CANCER RESEARCH

1956 • 1,729 citations

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B.

1989 • 1,660 citations

Electroporation for the efficient transfection of mammalian cells with DNA

1987 • 856 citations

The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump.

1994 • 685 citations

Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs.

1994 • 635 citations

The drug resistance-related protein LRP is the human major vault protein

1995 • 621 citations

Overexpression of a M(r) 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance.

1993 • 508 citations

Tissue distribution of the multidrug resistance protein.

1996 • 473 citations

Heterogeneity of malignant cells from a human colonic carcinoma.

1981 • 468 citations

Transcriptional repression of the GLUT4 and C/EBP genes in 3T3-L1 adipocytes by tumor necrosis factor-alpha.

1991 • 369 citations

Pleiotropic phenotype of colchicine‐resistant CHO cells: Cross‐resistance and collateral sensitivity

1976 • 314 citations

Isolation and sequence of the promoter region of the human multidrug-resistance (P-glycoprotein) gene.

1987 • 289 citations

Immunochemical detection of the multidrug resistance-associated protein MRP in human multidrug-resistant tumor cells by monoclonal antibodies.

1994 • 284 citations

Overexpression of the major vault transporter protein lung-resistance protein predicts treatment outcome in acute myeloid leukemia

1996 • 254 citations

Drug Resistance-Associated Marker Lrp for Prediction of Response to Chemotherapy and Prognoses in Advanced Ovarian Carcinoma

1995 • 225 citations

Overlapping phenotypes of multidrug resistance among panels of human cancer-cell lines

1996 • 214 citations

Evidence that vault ribonucleoprotein particles localize to the nuclear pore complex

1993 • 214 citations

Progress in Clinical and Biological Research

1983 • 206 citations

Broad distribution of the multidrug resistance-related vault lung resistance protein in normal human tissues and tumors.

1996 • 193 citations

Expression of the multidrug resistance-associated protein (MRP) gene in human cancers.

1995 • 174 citations

Multidrug-resistant phenotype of disease-oriented panels of human tumor cell lines used for anticancer drug screening.

1992 • 156 citations

A Y-box consensus sequence is required for basal expression of the human multidrug resistance (mdr1) gene.

1993 • 124 citations

Tumor necrosis factor activities and cancer therapy — A perspective

1993 • 119 citations

Biological and clinical effects of intravenous tumor necrosis factor-alpha administered three times weekly.

1991 • 112 citations

Sequential coexpression of the multidrug resistance genes MRP and mdr1 and their products in VP-16 (etoposide)-selected H69 small cell lung cancer cells.

1995 • 108 citations

Cytokines : a practical approach

1995 • 101 citations

Cloning and sequence analysis of the promoter region of the MRP gene of HL60 cells isolated for resistance to adriamycin.

1994 • 101 citations

NF-IL6, a member of the C/EBP family of transcription factors, binds and trans-activates the human MDR1 gene promoter.

1994 • 99 citations

Analysis of multidrug resistance-associated protein (MRP) messenger RNA in normal and malignant hematopoietic cells.

1994 • 97 citations

MRP and MDR1 gene expression in primary breast carcinomas.

1996 • 94 citations

Expression of multidrug resistance-associated protein (MRP), MDR1 and DNA topoisomerase II in human multidrug-resistant bladder cancer cell lines

1995 • 93 citations

Effects of TNF-alpha and phorbol ester on human surfactant protein and MnSOD gene transcription in vitro

1992 • 83 citations

Membrane transport proteins associated with drug resistance expressed in human melanoma.

1995 • 80 citations

Modulation of mdr1 expression by cytokines in human colon carcinoma cells: an approach for reversal of multidrug resistance

1996 • 72 citations

Reversal of Multidrug Resistance by Transduction of Cytokine Genes Into Human Colon Carcinoma Cells

1996 • 69 citations

Involvement of protein kinase in environmental stress‐induced activation of human multidrug resistance 1 (MDR1) gene promoter

1993 • 61 citations

Influence of cytokines onmdr1 expression in human colon carcinoma cell lines: Increased cytoxicity of MDR relevant drugs

1994 • 53 citations

Evidence that SP1 Modulates Transcriptional Activity of the Multidrug Resistance-Associated Protein Gene

1996 • 47 citations

The Mitogenic Response to Tumor Necrosis Factor Alpha Requires c-Jun/AP-1

1993 • 44 citations

Identification and characterization of a novel GGA/C-binding protein, GBP-i, that is rapidly inducible by cytokines.

1994 • 38 citations

Purification and characterization of NF-R1 that regulates the expression of the human multidrug resistance (MDR1) gene

1992 • 34 citations

Gene transfer of human TNFα into glioblastoma cells permits modulation of mdr1 expression and potentiation of chemosensitivity

1995 • 34 citations

Effects of tumor necrosis factor on sensitive and multidrug resistant human leukemia and myeloma cell lines

1989 • 33 citations

RNA analysis using miniprep RNA in reverse transcription PCR.

1994 • 28 citations

The mitogenic response to tumor necrosis factor alpha requires c-Jun/AP-1.

1993 • 27 citations

Pleiotropic Phenotype of Cultured Murine Cells Resistant to Maytansine, Vincristine, Colchicine, and Adriamycin23

1979 • 22 citations

Effect of erythromycin and tumour necrosis factor on the drug resistance of multidrug‐resistant cells: Reversal of drug resistance by erythromycin

1989 • 21 citations

Establishment of multidrug resistant human colorectal carcinoma HCT-15 cell lines and their properties.

1991 • 20 citations

Combined activity of interleukin-1 alpha or TNF-alpha and doxorubicin on multidrug resistant cell lines: evidence that TNF and DXR have synergistic antitumor and differentiation-inducing effects.

1994 • 19 citations

Potentiation of tumour necrosis factor-mediated cell killing by VP16 on human ovarian cancer cell lines. In vitro results and clinical implications

1993 • 13 citations

Effects of tumor necrosis factor α, interferon α and interferon γ on non-lymphoid leukemia cell lines: Growth inhibition, differentiation induction and drug sensitivity modulation

1992 • 12 citations

Pleiotropic resistance and drug development.

1986 • 4 citations