Expression of the Insulin-Like Growth Factor Binding Proteins during Postnatal Development of the Murine Mammary Gland

Cellular Actions of the Insulin-Like Growth Factor Binding Proteins

2002 • 1,717 citations

Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP-1, -2, -3, -4, -5 and -6)

1991 • 680 citations

Insulin-like growth factor (IGF)-binding proteins: interactions with IGFs and intrinsic bioactivities

2000 • 633 citations

Postnatal mammary gland development requires macrophages and eosinophils

2000 • 429 citations

Role of insulin-like growth factor binding proteins in controlling IGF actions

1998 • 401 citations

Nucleotide Sequence and Expression of a cDNA Clone Encoding a Fetal Rat Binding Protein for Insulin-like Growth Factors

1989 • 263 citations

Apoptosis in the terminal endbud of the murine mammary gland: a mechanism of ductal morphogenesis

1996 • 256 citations

Molecular Cloning of the cDNAs Encoding a Novel Insulin-Like Growth Factor-Binding Protein from Rat and Human

1990 • 239 citations

Isolation and Molecular Cloning of Insulin-Like Growth Factor-Binding Protein-6

1991 • 233 citations

Involution of the lactating mammary gland is inhibited by the IGF system in a transgenic mouse model.

1996 • 208 citations

Requirement of macrophages and eosinophils and their cytokines/chemokines for mammary gland development

2002 • 205 citations

Growth factor messenger RNA expression by human breast fibroblasts from benign and malignant lesions.

1991 • 204 citations

IGF-I: an essential factor in terminal end bud formation and ductal morphogenesis.

2000 • 171 citations

IGF-2 Is a Mediator of Prolactin-Induced Morphogenesis in the Breast

2002 • 168 citations

Targeted expression of des(1-3) human insulin-like growth factor I in transgenic mice influences mammary gland development and IGF-binding protein expression.

1996 • 164 citations

Hormonal Control of Insulin-Like Growth Factor-Binding Protein-5 Production in the Involuting Mammary Gland of the Rat¹

1997 • 153 citations

Targeted Disruption of the IGF-I Receptor Gene Decreases Cellular Proliferation in Mammary Terminal End Buds

2001 • 129 citations

The expression of the IGF family and GH receptor in the bovine mammary gland

2001 • 128 citations

Insulin-like growth factor binding protein-5 (IGFBP-5) induces premature cell death in the mammary glands of transgenic mice

2002 • 128 citations

Complementary DNA structure of the high molecular weight rat insulin-like growth factor binding protein (IGF-BP3) and tissue distribution of its mRNA

1989 • 125 citations

Evidence That the Mammary Fat Pad Mediates the Action of Growth Hormone in Mammary Gland Development

1998 • 119 citations

Disruption of Steroid and Prolactin Receptor Patterning in the Mammary Gland Correlates with a Block in Lobuloalveolar Development

2002 • 106 citations

Insulin-like growth factor expression in breast cancer epithelium and stroma

1992 • 105 citations

NON-LACTOGENIC EFFECTS OF GROWTH HORMONE ON GROWTH AND INSULIN-LIKE GROWTH FACTOR-I MESSENGER RIBONUCLEIC ACID OF RAT MAMMARY GLAND

1990 • 105 citations

Early mammary development: growth hormone and IGF-1.

1997 • 104 citations

Distinct expression patterns of insulin-like growth factor binding proteins 2 and 5 during fetal and postnatal development.

1994 • 104 citations

The localization of the insulin-like growth factor receptor 1 (IGFR-1) in benign and malignant breast tissue

1997 • 100 citations

Local Insulin-Like Growth Factor-II Mediates Prolactin-Induced Mammary Gland Development

2003 • 100 citations

Expression of IGF-I and IGF-II mRNA in breast tissue

1992 • 99 citations

Type I insulin-like growth factor receptor gene expression in normal human breast tissue treated with oestrogen and progesterone

1997 • 94 citations

Role of Prolactin, Growth Hormone and Insulin-Like Growth Factor 1 in Mammary Gland Involution in the Dairy Cow

2002 • 94 citations

Insulin-like growth factor (IGF) system in the bovine mammary gland and milk.

2000 • 88 citations

Insulin-like growth factor binding protein 5 and apoptosis in mammary epithelial cells

2003 • 87 citations

The Insulin-Like Growth Factors (IGF) and IGF Type I Receptor during Postnatal Growth of the Murine Mammary Gland: Sites of Messenger Ribonucleic Acid Expression and Potential Functions**This work was supported, in part, by NIH Grant DK-48103 (to T.L.W.)

1999 • 86 citations

The insulin-like growth factors (IGFs) and IGF binding proteins in postnatal development of murine mammary glands.

2000 • 82 citations

Insulin-like growth factor binding proteins: IGF-dependent and -independent effects in the mammary gland.

2000 • 73 citations

Local IGF-I axis in peripubertal ruminant mammary development.

2000 • 63 citations

Insulin-like Growth Factor Binding Protein-5 (IGFBP-5) Potentially Regulates Programmed Cell Death and Plasminogen Activation in the Mammary Gland

2005 • 56 citations

Requirement for IGF-I in Epidermal Growth Factor-Mediated Cell Cycle Progression of Mammary Epithelial Cells

2002 • 54 citations

Growth Hormone, Acting in Part through the Insulin-Like Growth Factor Axis, Rescues Developmental, But Not Metabolic, Activity in the Mammary Gland of Mice Expressing a Single Allele of the Prolactin Receptor

2002 • 45 citations

Mitogenic Properties of Insulin-Like Growth Factors I and II, Insulin-Like Growth Factor Binding Protein-3 and Epidermal Growth Factor on Human Breast Epithelial Cells in Primary Culture

2002 • 42 citations

The role of progestins, insulin-like growth factor (IGF) and IGF-binding proteins in the normal and neoplastic mammary gland of the bitch: a review.

1997 • 39 citations

Programmed cell death in the terminal endbud.

1999 • 38 citations

Identification of IGF binding proteins in bovine milk and the demonstration of IGFBP-3 synthesis and release by bovine mammary epithelial cells.

1999 • 34 citations

Inability of Overexpressed des(1–3)Human Insulin-Like Growth Factor I (IGF-I) to Inhibit Forced Mammary Gland Involution Is Associated with Decreased Expression of IGF Signaling Molecules*

2001 • 32 citations

Spatial and temporal expression of insulin-like growth factor-I, insulin-like growth factor-II and the insulin-like growth factor-I receptor in the sheep fetal mammary gland

1999 • 18 citations