Effect of differing doses of inhaled budesonide on markers of airway inflammation in patients with mild asthma

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1992 • 5,039 citations

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1972 • 4,731 citations

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1975 • 1,489 citations

Increased nitric oxide in exhaled air of asthmatic patients

1994 • 1,462 citations

Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements.

1996 • 964 citations

Effects of Reducing or Discontinuing Inhaled Budesonide in Patients with Mild Asthma

1994 • 755 citations

Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma.

1998 • 694 citations

Effect of Long-term Treatment with an Inhaled Corticosteroid (Budesonide) on Airway Hyperresponsiveness and Clinical Asthma in Nonsteroid-dependent Asthmatics

1990 • 613 citations

Inhaled glucocorticoids decrease nitric oxide in exhaled air of asthmatic patients.

1996 • 588 citations

Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD.

1997 • 564 citations

New concepts in the pathogenesis of bronchial hyperresponsiveness and asthma

1989 • 481 citations

Effects of 22 Months of Treatment with Inhaled Corticosteroids and/or Beta-2-Agonists on Lung Function, Airway Responsiveness, and Symptoms in Children with Asthma

1992 • 459 citations

A Comparison of Bronchodilator Therapy with or without Inhaled Corticosteroid Therapy for Obstructive Airways Disease

1992 • 354 citations

Increased exhaled nitric oxide in asthma is mainly derived from the lower respiratory tract.

1996 • 284 citations

Glucocorticoids inhibit cytokine-mediated eosinophil survival.

1991 • 274 citations

Sputum in severe exacerbations of asthma: kinetics of inflammatory indices after prednisone treatment.

1997 • 274 citations

Bronchial Subepithelial Fibrosis Correlates With Airway Responsiveness to Methacholine

1997 • 254 citations

Relationship between the inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids.

1996 • 246 citations

Cellular characteristics of sputum from patients with asthma and chronic bronchitis.

1989 • 244 citations

Measuring airway inflammation in asthma: Eosinophils and eosinophilic cationic protein in induced sputum compared with peripheral blood

1997 • 230 citations

A research method to induce and examine a mild exacerbation of asthma by withdrawal of inhaled corticosteroid

1992 • 200 citations

Repeatability of cellular and soluble markers of inflammation in induced sputum from patients with asthma

1996 • 190 citations

Budesonide delivered by Turbuhaler is effective in a dose-dependent fashion when used in the treatment of adult patients with chronic asthma

1998 • 187 citations

Time Course of Change in Bronchial Reactivity with an Inhaled Corticosteroid in Asthma

1991 • 184 citations

Analysis of induced sputum to examine the effects of prednisone on airway inflammation in asthmatic subjects

1994 • 158 citations

Dosage and Time Effects of Inhaled Budesonide on Bronchial Hyperreactivity

1988 • 156 citations

Peripheral blood CD4 but not CD8 t-lymphocytes in patients with exacerbation of asthma transcribe and translate messenger RNA encoding cytokines which prolong eosinophil survival in the context of a Th2-type pattern: effect of glucocorticoid therapy.

1995 • 150 citations

Effect of high dose inhaled fluticasone propionate on airway inflammation in asthma.

1995 • 146 citations

Glucocorticoids inhibit eosinophil responses to granulocyte-macrophage colony-stimulating factor.

1991 • 128 citations

Comparison of two methods of collecting induced sputum in asthmatic subjects

1996 • 127 citations

Long-term effects of budesonide on airway responsiveness and clinical asthma severity in inhaled steroid-dependent asthmatics

1990 • 106 citations

Pulmicort® turbohaler® once daily as initial prophylactic therapy for asthma

1994 • 99 citations

Sputum and blood eosinophils during corticosteroid treatment of acute exacerbations of asthma

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Glucocorticoids inhibit granulocyte-macrophage colony-stimulating factor-1 and interleukin-5 enhanced in vitro survival of human eosinophils.

1992 • 62 citations