Peripheral blood CD4 but not CD8 t-lymphocytes in patients with exacerbation of asthma transcribe and translate messenger RNA encoding cytokines which prolong eosinophil survival in the context of a Th2-type pattern: effect of glucocorticoid therapy.

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

Standards for the Diagnosis and Care of Patients with Chronic Obstructive Pulmonary Disease

1995 • 3,549 citations

Predominant T_H2-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma

1992 • 2,802 citations

Recombinant human interleukin 5 is a selective activator of human eosinophil function.

1988 • 976 citations

Identification of Activated T Lymphocytes and Eosinophils in Bronchial Biopsies in Stable Atopic Asthma

1990 • 890 citations

Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma.

1991 • 841 citations

Allergic and Nonallergic Asthmatics Have Distinct Patterns of T-Cell Activation and Cytokine Production in Peripheral Blood and Bronchoalveolar Lavage

1992 • 788 citations

Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival.

1986 • 733 citations

An improved immunomagnetic procedure for the isolation of highly purified human blood eosinophils

1991 • 628 citations

T cells and eosinophils in the pathogenesis of asthma

1992 • 585 citations

Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3.

1988 • 490 citations

Identification of T lymphocytes, Macrophages, and Activated Eosinophils in the Bronchial Mucosa in Intrinsic Asthma: Relationship to Symptoms and Bronchial Responsiveness

1992 • 414 citations

T cell subsets and their soluble products regulate eosinophilia in allergic and nonallergic asthma.

1991 • 395 citations

IL-5 enhances the in vitro adhesion of human eosinophils, but not neutrophils, in a leucocyte integrin (CD11/18)-dependent manner.

1990 • 328 citations

CD4 T-Lymphocyte Activation in Acute Severe Asthma: Relationship to Disease Severity and Atopic Status

1990 • 327 citations

Prednisolone Treatment in Asthma Is Associated with Modulation of Bronchoalveolar Lavage Cell Interleukin-4, Interleukin-5, and Interferon-γ Cytokine Gene Expression

1993 • 307 citations

IL-5-dependent conversion of normodense human eosinophils to the hypodense phenotype uses 3T3 fibroblasts for enhanced viability, accelerated hypodensity, and sustained antibody-dependent cytotoxicity.

1989 • 288 citations

CD4 T-Lymphocyte Activation in Asthma Is Accompanied by Increased Serum Concentrations of Interleukin-5: Effect of Glucocorticoid Therapy

1993 • 264 citations

Relationships among numbers of bronchoalveolar lavage cells expressing messenger ribonucleic acid for cytokines, asthma symptoms, and airway methacholine responsiveness in atopic asthma

1993 • 259 citations

Glucocorticoid Resistance in Chronic Asthma: Glucocorticoid Pharmacokinetics, Glucocorticoid Receptor Characteristics, and Inhibition of Peripheral Blood T Cell Proliferation by GlucocorticoidsIn Vitro

1991 • 255 citations

Activated T-lymphocytes and eosinophils in the bronchial mucosa in isocyanate-induced asthma

1992 • 224 citations

Fc gamma and CD11/CD18 receptor expression on normal density and low density human eosinophils.

1990 • 125 citations

294 Eosinophils, T-lymphocytes, mast cells, neutrophils and macrophages in bronchial biopsies from atopic asthmatics: Comparison with atopic non-asthma and relationship to bronchial hyperresponsiveness

1991 • 45 citations

Production of Interleukin-5 and Granulocyte/Macrophage Colony-stimulating Factor by T Cells of Patients with Bronchial Asthma in Response to Dermatophagoides farinae and Its Relation to Eosinophil Colony-stimulating Factor

1993 • 16 citations

Expression of Interleukin 5 by the CD4+CD45R0+ Subset of Human T Cells

1992 • 14 citations