Reactivation of isolated mitotic apparatus: Metaphase versus anaphase spindles

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cell Motility by Labile Association of Molecules

1967 • 767 citations

Tubulin dynamics in cultured mammalian cells.

1984 • 489 citations

Kinetochores are transported poleward along a single astral microtubule during chromosome attachment to the spindle in newt lung cells.

1990 • 488 citations

The Formation, Structure, and Composition of the Mammalian Kinetochore and Kinetochore Fiber

1982 • 428 citations

Sites of microtubule assembly and disassembly in the mitotic spindle

1986 • 410 citations

Polewards chromosome movement driven by microtubule depolymerization in vitro

1988 • 409 citations

Variant Mitoses in Lower Eukaryotes: Indicators of the Evolution of Mitosis?

1980 • 323 citations

Cell division and the mitotic spindle.

1981 • 323 citations

Chromosomes move poleward in anaphase along stationary microtubules that coordinately disassemble from their kinetochore ends.

1987 • 314 citations

Kinetochores capture astral microtubules during chromosome attachment to the mitotic spindle: direct visualization in live newt lung cells.

1990 • 312 citations

Spindle microtubule dynamics in sea urchin embryos: analysis using a fluorescein-labeled tubulin and measurements of fluorescence redistribution after laser photobleaching.

1984 • 291 citations

The Chromosome Cycle and the Centrosome Cycle in the Mitotic Cycle

1987 • 263 citations

Organization and Function of the Mitotic Spindle

1964 • 241 citations

Properties of the kinetochore in vitro. II. Microtubule capture and ATP-dependent translocation.

1985 • 239 citations

The Isolation and Biochemical Characterization of the Mitotic Apparatus of Dividing Cells

1952 • 225 citations

Structural polarity of kinetochore microtubules in PtK1 cells.

1981 • 218 citations

Microtubule Dynamics and Kinetochore Function in Mitosis

1988 • 208 citations

The motor for poleward chromosome movement in anaphase is in or near the kinetochore.

1989 • 202 citations

Rethinking mitosis

1982 • 195 citations

The Evolution of the Mitotic Spindle

1976 • 194 citations

SOME STRUCTURAL AND FUNCTIONAL ASPECTS OF THE MITOTIC APPARATUS IN SEA URCHIN EMBRYOS

1962 • 192 citations

Light and electron microscopy of rat kangaroo cells in mitosis

1976 • 187 citations

Light and electron microscopy of rat kangaroo cells in mitosis

1973 • 175 citations

THE ANAPHASE MOVEMENT OF CHROMOSOMES IN THE SPERMATOCYTES OF THE GRASSHOPPER

1949 • 174 citations

Mechanics of chromosome separation during mitosis in Fusarium (Fungi imperfecti): new evidence from ultrastructural and laser microbeam experiments.

1981 • 169 citations

Chromosome micromanipulation

1967 • 164 citations

Polarity of microtubules nucleated by centrosomes and chromosomes of Chinese hamster ovary cells in vitro

1980 • 155 citations

Mitosis

1989 • 155 citations

Isolation of mitotic apparatus containing vesicles with calcium sequestration activity

1980 • 148 citations

Removal of the fertilization membrane of sea urchin embryos employing aminotriazole

1979 • 148 citations

Functional autonomy of monopolar spindle and evidence for oscillatory movement in mitosis.

1982 • 145 citations

Properties of the kinetochore in vitro. I. Microtubule nucleation and tubulin binding.

1985 • 143 citations

Interzone microtubule behavior in late anaphase and telophase spindles.

1987 • 134 citations

Decoration of spindle microtubules with Dynein: evidence for uniform polarity.

1981 • 126 citations

Characteristics of the polar assembly and disassembly of microtubules observed in vitro by darkfield light microscopy.

1979 • 116 citations

Analysis of the treadmilling model during metaphase of mitosis using fluorescence redistribution after photobleaching.

1986 • 106 citations

Reversible restoration of the birefringence of cold-treated, isolated mitotic apparatus of surf clam eggs with chick brain tubulin

1974 • 97 citations

In vitro reactivation of anaphase spindle elongation using isolated diatom spindles

1985 • 93 citations

Heterogeneity of vertebrate brain tubulins.

1984 • 80 citations

Isolation of microtubule protein from chicken erythrocytes and determination of the critical concentration for tubulin polymerization in vitro and in vivo.

1983 • 74 citations

Temperature and ph govern the self-assembly of microtubules from unfertilized sea-urchin egg extracts

1987 • 73 citations

Mechanisms of chromosome distribution and aneuploidy

1991 • 73 citations

Brain and erythrocyte microtubules from chicken contain different beta-tubulin polypeptides.

1983 • 70 citations

The polarity and stability of microtubule capture by the kinetochore.

1988 • 68 citations

In vitro reactivation of spindle elongation in fission yeast nuc2 mutant cells.

1990 • 66 citations

Proteins specifically associated with the microtubules of the mammalian mitotic spindle

1982 • 63 citations

The role of tubulin polymerization during spindle elongation in vitro

1987 • 60 citations

Assembly properties of fluorescein-labeled tubulin in vitro before and after fluorescence bleaching.

1984 • 58 citations

The mechanism of anaphase spindle elongation: uncoupling of tubulin incorporation and microtubule sliding during in vitro spindle reactivation.

1988 • 58 citations

Micromanipulation studies of chromosome movement. II. Birefringent chromosomal fibers and the mechanical attachment of chromosomes to the spindle.

1979 • 57 citations

Strongylocentrotus purpuratus spindle tubulin. I. Characteristics of its polymerization and depolymerization in vitro.

1982 • 53 citations

Physiological and ultrastructural analysis of elongating mitotic spindles reactivated in vitro.

1986 • 47 citations

Purification, characterization, and assembly properties of tubulin from unfertilized eggs of the sea urchin Strongylocentrotus purpuratus

1983 • 46 citations

Quantitative studies on the polarization optical properties of living cells II. The role of microtubules in birefringence of the spindle of the sea urchin egg.

1981 • 46 citations

Micromanipulation studies of the mitotic apparatus in sand dollar eggs

1988 • 44 citations

SOME OBSERVATIONS CONCERNING METAKINESIS IN SEA URCHIN EGGS

1965 • 41 citations

Control of isotubulin expression during neuronal differentiation of mouse neuroblastoma and teratocarcinoma cell lines

1987 • 40 citations

Anaphase motions in dilute colchicine

1973 • 39 citations

Biotin-tubulin incorporates into kinetochore fiber microtubules during early but not late anaphase.

1989 • 36 citations

Purification and characterization of oocyte cytoplasmic tubulin and meiotic spindle tubulin of the surf clam Spisula solidissima.

1984 • 34 citations

Strongylocentrotus purpuratus spindle tubulin. II. Characteristics of its sensitivity to Ca++ and the effects of calmodulin isolated from bovine brain and S. purpuratus eggs.

1982 • 34 citations

Microtubule dynamics in the spindle. Theoretical aspects of assembly/disassembly reactions in vivo

1986 • 31 citations

In vitro reactivation of anaphase B in isolated spindles of the sea urchin egg

1988 • 30 citations

The diversity of mitosis: the value of evolutionary experiments

1988 • 23 citations

Purification of meiotic spindles and cytoplasmic asters from mouse oocytes

1988 • 13 citations

The stabilization of microtubules in isolated spindles by tubulin‐colchicine complex

1986 • 9 citations

The Isolated Mitotic Apparatus: A Model System for Studying Mitotic Mechanisms

1981 • 8 citations

Interaction of bimane‐labeled fluorescent tubulin with the isolated mitotic apparatus

1984 • 7 citations

Incorporation and turnover of labeled exogenous tubulin in the mitotic spindles of Chaetopterus oocytes and HeLa cells

1986 • 3 citations