Oncostatin M, leukemia inhibitory factor, and interleukin 6 induce the proliferation of human plasmacytoma cells via the common signal transducer, gp130.

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

1988 • 1,698 citations

Molecular cloning and expression of an IL-6 signal transducer, gp130

1990 • 1,307 citations

The IL-6 Signal Transducer, gp130: an Pncostatin M Receptor and Affinity Converter for the LIF Receptor

1992 • 897 citations

Interleukin-6 and Its Receptor: A Paradigm for Cytokines

1992 • 889 citations

Paracrine rather than autocrine regulation of myeloma-cell growth and differentiation by interleukin-6

1989 • 775 citations

Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor.

1987 • 690 citations

Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine.

1990 • 649 citations

Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor

1989 • 624 citations

Murine anti-interleukin-6 monoclonal antibody therapy for a patient with plasma cell leukemia

1991 • 419 citations

A Macrophage-Derived Factor Required by Plasmacytomas for Survival and Proliferation in Vitro

1986 • 391 citations

Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6.

1991 • 372 citations

Reshaping a human antibody to inhibit the interleukin 6-dependent tumor cell growth.

1993 • 269 citations

Studies on the clonal origin of multiple myeloma. Use of individually specific (idiotype) antibodies to trace the oncogenic event to its earliest point of expression in B-cell differentiation.

1979 • 255 citations

Multiple myeloma: significance of plasmablastic subtype in morphological classification

1985 • 249 citations

Identification of a Major Growth Factor for AIDS-Kaposi's Sarcoma Cells as Oncostatin M

1992 • 227 citations

Functional inhibition of hematopoietic and neurotrophic cytokines by blocking the interleukin 6 signal transducer gp130.

1992 • 206 citations

Characterization of IL-6 receptor expression by monoclonal and polyclonal antibodies.

1989 • 179 citations

Leukemia inhibitory factor: A biological perspective

1991 • 167 citations

Identification of malignant plasma cell precursors in the bone marrow of multiple myeloma.

1985 • 160 citations

Characterization of adhesion molecules on human myeloma cell lines

1992 • 150 citations

Interleukin-6 signal transducer gp130 mediates oncostatin M signaling.

1992 • 147 citations

Identification of immature and mature myeloma cells in the bone marrow of human myelomas

1993 • 145 citations

Leukemia inhibitory factor is expressed in cartilage and synovium and can contribute to the pathogenesis of arthritis.

1992 • 127 citations

Lack of a role of interleukin 11 in the growth of multiple myeloma

1992 • 43 citations

Separation of human myeloma cells from bone marrow aspirates in multiple myeloma and their proliferation and M-protein secretion in vitro

1988 • 42 citations

Preparation of monoclonal antibodies against the IL-6 signal transducer, gp130, that can inhibit IL-6-mediated functions

1993 • 41 citations

Homotypic cell aggregations of human myeloma cells with ICAM‐1 and LFA‐1 molecules

1991 • 41 citations

A new highly sensitive immunoassay for cytokines by dissociation-enhanced lanthanide fluoroimmunoassay (DELFIA)

1992 • 40 citations

Interleukin-11 and its receptor.

1992 • 39 citations