Infection, inflammation, and infarction: does acute endothelial dysfunction provide a link?

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

The Pathogenesis of Atherosclerosis — An Update

1986 • 4,951 citations

Elevated Circulating Levels of Tumor Necrosis Factor in Severe Chronic Heart Failure

1990 • 2,566 citations

The Prognostic Value of C-Reactive Protein and Serum Amyloid A Protein in Severe Unstable Angina

1994 • 2,343 citations

Regulatory Functions of the Vascular Endothelium

1990 • 1,899 citations

Modulation of coronary vasomotor tone in humans. Progressive endothelial dysfunction with different early stages of coronary atherosclerosis.

1991 • 1,010 citations

Molecular mechanisms and therapeutic strategies related to nitric oxide

1995 • 791 citations

Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life.

1993 • 778 citations

Physical Training Improves Endothelial Function in Patients With Chronic Heart Failure

1996 • 638 citations

Seasonal variations of plasma fibrinogen and factor VII activity in the elderly: winter infections and death from cardiovascular disease

1994 • 541 citations

Inhibition and stimulation of nitric oxide synthesis in the human forearm arterial bed of patients with insulin-dependent diabetes.

1992 • 527 citations

Impaired endothelium-dependent vasodilation of forearm resistance vessels in hypercholesterolaemia

1992 • 475 citations

Demonstration of an inducible cyclooxygenase in human endothelial cells using antibodies raised against the carboxyl-terminal region of the cyclooxygenase-2.

1993 • 293 citations

Reduced Gene Expression of Vascular Endothelial NO Synthase and Cyclooxygenase-1 in Heart Failure

1996 • 271 citations

Administration of tumor necrosis factor-alpha in vivo depresses endothelium-dependent relaxation

1994 • 153 citations

Endothelial "stunning" following a brief exposure to endotoxin: a mechanism to link infection and infarction?

1996 • 148 citations

Excess Deaths Attributable to Influenza in England and Wales: Age at Death and Certified Cause

1983 • 147 citations

Procoagulant Activity of Endothelial Cells after Infection with Respiratory Viruses

2000 • 125 citations

Functional activities of receptors for tumor necrosis factor-alpha on human vascular endothelial cells

1994 • 106 citations

Cardiac receptor activation and arrhythmogenesis

1993 • 84 citations

Portal endotoxin and cytokine responses during abdominal aortic surgery

1993 • 68 citations

Interleukin-8 as a sensitive marker of unstable coronary artery disease

1996 • 54 citations

Infection of Endothelial Cells by Common Human Viruses

1989 • 51 citations

EFFECTS OF CYTOKINES TUMOR NECROSIS FACTOR α AND INTERLEUKIN 1β ON ENDOTOXIN-MEDIATED INHIBITION OF ENDOTHELIUM-DERIVED RELAXING FACTOR BIOACTIVITY AND NITRIC OXIDE PRODUCTION IN VASCULAR ENDOTHELIUM

1994 • 40 citations

Interleukin-1α As a Factor in Occlusive Vascular Disease

1992 • 33 citations

Splanchnic vascular endothelial dysfunction in rat endotoxemia: role of superoxide radicals

1992 • 27 citations

Unreported symptomatic and asymptomatic ischaemic heart disease in patients presenting with TIA or minor stroke detected by the London School of Hygiene Cardiovascular Questionnaire and Minnesota coding of a routine ECG.

1987 • 5 citations