Ovarian cancer BRCA1 mutation detection: Protein truncation test (PTT) outperforms single strand conformation polymorphism analysis (SSCP)

Promoter Hypermethylation and BRCA1 Inactivation in Sporadic Breast and Ovarian Tumors

2000 • 1,182 citations

Nonsense-mediated mRNA decayin health and disease

1999 • 974 citations

Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families

1994 • 626 citations

Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer

1994 • 389 citations

Growth retardation and tumour inhibition by BRCA1

1996 • 360 citations

BRCA1 promoter region hypermethylation in ovarian carcinoma: a population-based study.

2000 • 322 citations

Roles of BRCA1 and its interacting proteins

2000 • 318 citations

Rapid detection of BRCA1 mutations by the protein truncation test

1995 • 317 citations

BRCA1 and BRCA2 Mutation Analysis of 208 Ashkenazi Jewish Women with Ovarian Cancer

2000 • 311 citations

Functional analysis of BRCA1 C-terminal missense mutations identified in breast and ovarian cancer families

2001 • 178 citations

The Exon 13 Duplication in the BRCA1 Gene Is a Founder Mutation Present in Geographically Diverse Populations

2000 • 102 citations

An abundance of p53 null mutations in ovarian carcinoma.

1996 • 102 citations

Abnormal expression of BRCA1 and BRCA1-interactive DNA-repair proteins in breast carcinomas

2000 • 92 citations

Germline mutation of BRCA1 in Japanese breast cancer families.

1995 • 74 citations

Ovarian cancer BRCA1 gene therapy: Phase I and II trial differences in immune response and vector stability.

1999 • 72 citations

A phase I trial of retroviral BRCA1sv gene therapy in ovarian cancer.

1997 • 66 citations

Comparison of conformation-sensitive gel electrophoresis and single-strand conformation polymorphism analysis for detection of mutations in the BRCA1 gene using optimized conformation analysis protocols

1998 • 56 citations

BRCA1 Mutations in Familial Ovarian Cancer

1999 • 20 citations

Optimization of PCR and Electrophoresis Conditions Enhances Mutation Analysis of the BRCA1 Gene

1998 • 14 citations

Laboratory Determination of Hereditary Susceptibility to Breast and Ovarian Cancer

1999 • 11 citations

Mutation Detection in the Breast Cancer Gene BRCA1 Using the Protein Truncation Test

2000 • 3 citations