Differential cell permeability and the basis for selective activity of methotrexate during therapy of the L1210 leukemia.

Temporary Remissions in Acute Leukemia in Children Produced by Folic Acid Antagonist, 4-Aminopteroyl-Glutamic Acid (Aminopterin)

1948 • 1,702 citations

Design of Active-Site-Directed Irreversible Enzyme Inhibitors.

1967 • 387 citations

Carrier-mediated Transport of the Folic Acid Analogue, Methotrexate, in the L1210 Leukemia Cell

1968 • 384 citations

THE BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ACTION AND EFFECTS OF THE FOLIC ACID ANTAGONISTS.

1963 • 156 citations

Uptake as a Determinant of Methotrexate Response in Mouse Leukemias

1965 • 107 citations

SITES OF ACTION OF AMETHOPTERIN: INTRINSIC AND ACQUIRED DRUG RESISTANCE*

1971 • 87 citations

On the nature of permeability of sarcoma-180 cells to amethopterin in vitro

1965 • 57 citations

Cellular Effects of Anticancer Drugs

1963 • 53 citations

Transport of methotrexate by the choroid plexus.

1968 • 53 citations

Comparative studies on the transport of aminopterin, methotrexate, and methasquin by the L1210 leukemia cell.

1972 • 50 citations

Cytotoxic effects of 1-beta-D-arabinofuranosyl-5-fluorocytosine and of 1-beta-D-arabinofuranosylcytosine in proliferating tissues in mice.

1969 • 43 citations

Active transport of aminopterin in Yoshida sarcoma cells

1967 • 32 citations

TISSUE DISTRIBUTION OF FOLATE ANTAGONISTS

1971 • 21 citations