Rosiglitazone, a PPAR gamma agonist: Potent promoter of hydroxybutyl(butyl)nitrosamine‐induced urinary bladder cancers

Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial

2005 • 4,040 citations

Central Role of Peroxisome Proliferator–Activated Receptors in the Actions of Peroxisome Proliferators

2000 • 336 citations

Celecoxib inhibits N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder cancers in male B6D2F1 mice and female Fischer-344 rats.

2000 • 263 citations

13- cis -Retinoic Acid: Inhibition of Bladder Carcinogenesis in the Rat

1977 • 256 citations

A new ligand for the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), GW7845, inhibits rat mammary carcinogenesis.

1999 • 234 citations

Chemoprevention of mammary carcinoma by LGD1069 (Targretin): an RXR-selective ligand.

1996 • 202 citations

The retinoid X receptor-selective retinoid, LGD1069, prevents the development of estrogen receptor-negative mammary tumors in transgenic mice.

2002 • 163 citations

Chemopreventive effects of nimesulide, a selective cyclooxygenase-2 inhibitor, on the development of rat urinary bladder carcinomas initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.

1998 • 134 citations

Multiple expression control mechanisms of peroxisome proliferator-activated receptors and their target genes

2005 • 121 citations

Differential Regulation of Vascular Endothelial Growth Factor Expression by Peroxisome Proliferator-activated Receptors in Bladder Cancer Cells

2002 • 115 citations

13- cis -Retinoic Acid: Inhibition of Bladder Carcinogenesis Induced in Rats by N -Butyl- N -(4-hydroxybutyl)nitrosamine

1977 • 112 citations

MOLECULAR EPIDEMIOLOGY AND CANCER PREVENTION: Differential activity of aspirin, ketoprofen and sulindac as cancer chemopreventive agents in the mouse urinary bladder

1996 • 103 citations

Central role of PPARα in the mechanism of action of hepatocarcinogenic peroxisome proliferators

2000 • 101 citations

Urothelial Carcinogenesis in the Urinary Bladder of Male Rats Treated with Muraglitazar, a PPARα/γ Agonist: Evidence for Urolithiasis as the Inciting Event in the Mode of Action

2006 • 91 citations

N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder cancer in C57BL/6 X DBA/2 F1 mice as a useful model for study of chemoprevention of cancer with retinoids.

1981 • 75 citations

Effect of regenerative hyperplasia on the urinary bladder: carcinogenicity of sodium saccharin and N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.

1982 • 58 citations

Biomarkers for early effects of carcinogenic dual-acting PPAR agonists in rat urinary bladder urotheliumin vivo

2005 • 51 citations

Preventive effects of Polyphenon E on urinary bladder and mammary cancers in rats and correlations with serum and urine levels of tea polyphenols

2007 • 38 citations

Gene Expression Profiling of Chemically Induced Rat Bladder Tumors

2007 • 34 citations

4-Hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers in mice: characterization of FHIT and survivin expression and chemopreventive effects of indomethacin

2004 • 30 citations

CpG methylation in the Fhit regulatory region: relation to Fhit expression in murine tumors

2004 • 25 citations

Spotlight on Rosiglitazone in the Management of Type 2 Diabetes Mellitus*

2002 • 4 citations

Effects of celecoxib, polyphenon E and rosiglitazone on hydroxybutyl(butyl)-nitrosamine (OH-BBN) –induced urinary bladder cancers in female Fischer-344 rats.

2004 • 3 citations