CpG methylation in the Fhit regulatory region: relation to Fhit expression in murine tumors

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

1996 • 5,667 citations

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

1999 • 1,865 citations

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma.

1994 • 1,542 citations

The FHIT Gene, Spanning the Chromosome 3p14.2 Fragile Site and Renal Carcinoma–Associated t(3;8) Breakpoint, Is Abnormal in Digestive Tract Cancers

1996 • 1,008 citations

The FHIT Gene at 3p14.2 Is Abnormal in Lung Cancer

1996 • 547 citations

Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours

2001 • 379 citations

DNA methylation and gene silencing in cancer: which is the guilty party?

2002 • 288 citations

Muir–Torre-like syndrome in Fhit-deficient mice

2000 • 178 citations

FRA3B and other common fragile sites: the weakest links

2001 • 177 citations

Detection of 1p and 19q Loss in Oligodendroglioma by Quantitative Microsatellite Analysis, a Real-Time Quantitative Polymerase Chain Reaction Assay

2001 • 172 citations

The tumor spectrum in FHIT- deficient mice

2001 • 164 citations

FHIT gene therapy prevents tumor development in Fhit-deficient mice

2001 • 129 citations

DNA methyltransferase 3b contributes to oncogenic transformation induced by SV40T antigen and activated Ras

2003 • 92 citations

Loss of FHIT Expression in Transitional Cell Carcinoma of the Urinary Bladder

2000 • 66 citations

The histone deacetylase inhibitor trichostatin A reduces nickel-induced gene silencing in yeast and mammalian cells

2001 • 43 citations

Quantitative PCR identifies a minimal deleted region of 120 kb extending from the Philadelphia chromosome ABL translocation breakpoint in chronic myeloid leukemia with poor outcome

2003 • 33 citations