Metformin Treatment for Four Years to Reduce Total and Visceral Fat in Low Birth Weight Girls with Precocious Pubarche

Role of AMP-activated protein kinase in mechanism of metformin action

2001 • 5,086 citations

The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin

2005 • 1,901 citations

Association between postnatal catch-up growth and obesity in childhood: prospective cohort study

2000 • 1,615 citations

Early Development of Adiposity and Insulin Resistance after Catch-Up Weight Gain in Small-for-Gestational-Age Children

2006 • 528 citations

Precocious Pubarche, Hyperinsulinism, and Ovarian Hyperandrogenism in Girls: Relation to Reduced Fetal Growth

1998 • 490 citations

Metabolic effects of metformin on glucose and lactate metabolism in noninsulin-dependent diabetes mellitus.

1996 • 410 citations

Measurement Issues Related to Studies of Childhood Obesity: Assessment of Body Composition, Body Fat Distribution, Physical Activity, and Food Intake

1998 • 359 citations

The blooming of the French lilac

2001 • 355 citations

High Visceral and Low Abdominal Subcutaneous Fat Stores in the Obese Adolescent

2007 • 348 citations

Metformin has direct effects on human ovarian steroidogenesis

2003 • 232 citations

Sensitization to Insulin in Adolescent Girls to Normalize Hirsutism, Hyperandrogenism, Oligomenorrhea, Dyslipidemia, and Hyperinsulinism after Precocious Pubarche1

2000 • 180 citations

Early Puberty-Menarche After Precocious Pubarche: Relation to Prenatal Growth

2006 • 173 citations

Effects of Metformin on Bovine Granulosa Cells Steroidogenesis: Possible Involvement of Adenosine 5′ Monophosphate-Activated Protein Kinase (AMPK)1

2006 • 167 citations

Sensitization to Insulin Induces Ovulation in Nonobese Adolescents with Anovulatory Hyperandrogenism

2001 • 162 citations

Identification of potential caloric restriction mimetics by microarray profiling

2005 • 157 citations

Early Development of Visceral Fat Excess after Spontaneous Catch-Up Growth in Children with Low Birth Weight

2007 • 147 citations

Insulin sensitization early after menarche prevents progression from precocious pubarche to polycystic ovary syndrome

2004 • 142 citations

Fat distribution in non‐obese girls with and without precocious pubarche: central adiposity related to insulinaemia and androgenaemia from prepuberty to postmenarche

2003 • 139 citations

Metformin Treatment to Prevent Early Puberty in Girls with Precocious Pubarche

2006 • 130 citations

Metformin Therapy during Puberty Delays Menarche, Prolongs Pubertal Growth, and Augments Adult Height: A Randomized Study in Low-Birth-Weight Girls with Early-Normal Onset of Puberty

2006 • 125 citations

Insulin Sensitization for Girls with Precocious Pubarche and with Risk for Polycystic Ovary Syndrome: Effects of Prepubertal Initiation and Postpubertal Discontinuation of Metformin Treatment

2004 • 123 citations

High Molecular Weight, Rather than Total, Adiponectin Levels Better Reflect Metabolic Abnormalities Associated with Childhood Obesity

2006 • 118 citations

Racial Differences in Adiponectin in Youth: Relationship to visceral fat and insulin sensitivityv

2006 • 90 citations

Racial Differences in Adiponectin in Youth

2006 • 85 citations

Association Between Postnatal Catch-Up Growth and Obesity in Childhood: Prospective Cohort Study

2000 • 75 citations

Pioglitazone (7·5 mg/day) added to flutamide–metformin in women with androgen excess: additional increments of visfatin and high molecular weight adiponectin

2007 • 26 citations

Body Composition, Dietary Intake, and Energy Expenditure in Nonobese, Prepubertal Children of Obese and Nonobese Biological Mothers

1999 • 21 citations

Persisting benefits 12–18 months after discontinuation of pubertal metformin therapy in low birthweight girls

2007 • 20 citations