Model Systems for Study of Perturbations of Myelin Metabolism

Methods of Enzymology.

1956 • 1,750 citations

Handbook of Neurochemistry

1972 • 1,374 citations

PROTEOLIPIDES, A NEW TYPE OF TISSUE LIPOPROTEINS

1951 • 773 citations

THE INFLAMMATORY LESION IN IDIOPATHIC POLYNEURITIS

1969 • 708 citations

MYELINATION IN RAT BRAIN: CHANGES IN MYELIN COMPOSITION DURING BRAIN MATURATION¹

1973 • 655 citations

The Activation of Mononuclear Phagocytes: Fact, Fancy, and Future

1978 • 609 citations

Glial cells and the central myelin sheath.

1968 • 530 citations

Experimental allergic encephalomyelitis

1969 • 406 citations

Studies of Schwann cell proliferation. I. An analysis in tissue culture of proliferation during development, Wallerian degeneration, and direct injury.

1980 • 402 citations

MYELINATION AS A VULNERABLE PERIOD IN BRAIN DEVELOPMENT

1966 • 383 citations

ULTRASTRUCTURAL STUDIES OF THE DYING-BACK PROCESS

1974 • 367 citations

Myelin-associated glycoprotein demonstrated immunocytochemically in myelin and myelin-forming cells of developing rat.

1979 • 360 citations

Maturation of human white matter myelin. Fractionation of the myelin membrane proteins

1968 • 343 citations

Pathogenesis of Demyelination Induced by a Mouse Hepatitis

1973 • 340 citations

Association between rise in serum sodium and central pontine myelinolysis

1982 • 302 citations

Central nervous system demyelination and remyelination in the mouse: an ultrastructural study of cuprizone toxicity.

1978 • 293 citations

Lead encephalo-myelopathy of the suckling rat and its implications on the porphyrinopathic nervous diseases

1966 • 289 citations

Diphtheria toxin forms transmembrane channels in planar lipid bilayers.

1981 • 281 citations

FINE STRUCTURE AND ELECTROLYTE ANALYSES OF CEREBRAL EDEMA INDUCED BY ALKYL TIN INTOXICATION

1963 • 273 citations

Mechanism of demyelination in JHM virus encephalomyelitis

1973 • 253 citations

The Application of Tissue Culture to the Study of Experimental “Allergic” Encephalomyelitis*

1961 • 246 citations

Immunocytochemical observations on the distribution of myelin‐associated glycoprotein and myelin basic protein in multiple sclerosis lesions

1980 • 240 citations

Progress in neuropathology

1971 • 225 citations

Mechanism of demyelination in experimental allergic neuritis. Electron microscopic studies.

1969 • 224 citations

DEMYELINATION AND REMYELINATION IN LEAD NEUROPATHY ELECTRON MICROSCOPIC STUDIES

1968 • 222 citations

ELECTRON MICROSCOPIC STUDIES ON THE VASCULAR PERMEABILITY AND THE MECHANISM OF DEMYELINATION IN EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS*†

1965 • 221 citations

Diabetic Neuropathy—New Concepts of Its Etiology

1979 • 218 citations

A third neuroglial cell types. An electron microscopic study

1968 • 217 citations

Experimental Allergic Neuritis Induced by Sensitization with Galactocerebroside

1979 • 212 citations

Demyelination of the superior cerebellar peduncle in the mouse induced by cuprizone

1973 • 205 citations

Ca2+-accumulation in experimental spinal cord trauma

1981 • 199 citations

The effect of neonatal thyroidectomy on myelination in the rat brain

1969 • 195 citations

The in vivo and ultrastructural effects of injection of lysophosphatidyl choline into myelinated peripheral nerve fibres of the adult mouse

1971 • 194 citations

The cellular reaction to wallerian degeneration in the central nervous system of the cat

1969 • 190 citations

Myelin development and nutritional insufficiency

1982 • 190 citations

Cerebroside Antibody Inhibits Sulfatide Synthesis and Myelination and Demyelinates in Cord Tissue Cultures

1974 • 186 citations

COPPER DEFICIENCY IN THE DEVELOPING RAT BRAIN: A POSSIBLE MODEL FOR MENKES’ STEELY‐HAIR DISEASE

1974 • 183 citations

Pattern of remyelination in the CNS

1974 • 175 citations

INVASION OF SCHWANN CELLS INTO THE SPINAL CORD OF THE RAT FOLLOWING LOCAL INJECTIONS OF LYSOLECITHIN

1976 • 171 citations

Remyelination of the superior cerebellar peduncle in the mouse following demyelination induced by feeding cuprizone

1973 • 169 citations

THE EFFECT OF MALNUTRITION ON THE SYNTHESIS OF A MYELIN LIPID

1967 • 169 citations

Electron microscopic studies on ordinary and hyperacute experimental allergic encephalomyelitis

1967 • 167 citations

Behavioral and biochemical interactions of 5,7-dihydroxy-tryptamine with various drugs when administered intracisternally to adult and developing rats

1975 • 166 citations

Pathogenesis of Lead Encephalopathy

1974 • 163 citations

Multiple sclerosis; a correlation of its incidence with dietary fat.

1950 • 161 citations

The role of oligodendroglia and astroglia in wallerian degeneration of the optic nerve

1973 • 160 citations

Regeneration of Oligodendroglia During Recovery from Demyelinating Disease

1977 • 159 citations

Lipid class and fatty acid composition of intact peripheral nerve and during wallerian degeneration

1965 • 149 citations

Susceptibility of the Myelin‐Associated Glycoprotein and Basic Protein to a Neutral Protease in Highly Purified Myelin from Human and Rat Brain

1982 • 148 citations

Giant Hepatic Mitochondria: Production in Mice Fed with Cuprizone

1969 • 147 citations

Chronic experimental allergic encephalomyelitis in inbred guinea pigs. An ultrastructural study.

1974 • 144 citations

Multiple sclerosis: vitamin D and calcium as environmental determinants of prevalence

1974 • 142 citations

In vivo demyelination induced by intraneural injection of anti-galactocerebroside serum: a morphologic study.

1979 • 141 citations

TISSUE CULTURE STUDIES OF DEMYELINATION^*

1965 • 137 citations

Chemical Pathology of the Nervous System

1962 • 136 citations

CREUTZFELDT-JAKOB DISEASE; 1. Survey of The Literature and Clinical Diagnosis

1968 • 136 citations

Hyperphenylalaninemia: Disaggregation of Brain Polyribosomes in Young Rats

1970 • 131 citations

Molecular behaviour of glycosphingolipids in interfaces Possible participation in some properties of nerve membranes

1981 • 129 citations

Chemical constituents of R.Br.

1964 • 127 citations

Chronic demyelination inhibits remyelination in the central nervous system. An analysis of contributing factors.

1980 • 125 citations

Undernutrition in the developing rat: effect upon myelination

1976 • 124 citations

MODIFICATION OF THE SCHEDULE OF MYELINATION IN THE RAT BY EARLY NUTRITIONAL DEPRIVATION

1966 • 121 citations

Effects of Altered Thyroid States on Myelinogenesis

1981 • 118 citations

An autoradiographic study of cellular proliferation in remyelination of the central nervous system.

1979 • 116 citations

The in vitro demyelinating activity of sera from guinea pigs sensitized with whole CNS and with purified encephalitogen

1968 • 115 citations

Myelin synthesis during postnatal nutritional deprivation and subsequent rehabilitation

1976 • 114 citations

Proteinase inhibitors suppress the development of experimental allergic encephalomyelitis

1980 • 114 citations

Neuropathological Findings in Phenyl-Pyruvic Oligophrenia (Phenyl-Ketonuria)

1950 • 113 citations

INFLUENCE OF THYROID ON FORMATION OF MYELIN LIPIDS ¹

1969 • 112 citations

QUANTITATIVE BIOCHEMICAL STUDIES OF WALLERIAN DEGENERATION IN THE PERIPHERAL AND CENTRAL NERVOUS SYSTEMS—I

1959 • 108 citations

Specific interaction of central nervous system myelin basic protein with lipids. Specific regions of the protein sequence protected from the proteolytic action of trypsin

1973 • 108 citations

ENZYMIC ACTIVITIES AND SODIUM, POTASSIUM AND COPPER CONCENTRATIONS IN MOUSE BRAIN AND LIVER AFTER CUPRIZONE TREATMENT IN VIVO

1973 • 106 citations

Augmentation of immune-mediated demyelination by lipid haptens.

1981 • 106 citations

Increased protease activity and changes in basic proteins and lipids in multiple sclerosis plaques

1970 • 106 citations

The perineurial window — a new model of focal demyelination and remyelination

1975 • 105 citations

The PO glycoprotein of peripheral nerve myelin

1980 • 104 citations

EXPERIMENTAL STUDY OF DIPHTHERITIC POLYNEURITIS IN THE RABBIT AND GUINEA PIG

1957 • 104 citations

Investigations on myelination in vitro. Regulation by thyroid hormone in cultures of dissociated brain cells from embryonic mice.

1979 • 104 citations

Experimental allergic encephalomyelitis: an ultrastructural study of experimental demyelination in vitro.

1970 • 102 citations

Mouse Hepatitis Virus-Induced Recurrent Demyelination

1975 • 101 citations

Proteolysis and myelin breakdown: a review of recent histochemical and biochemical studies

1969 • 101 citations

Experimental allergic encephalomyelitis. Antiserum inhibition of myelination in vitro.

1970 • 101 citations

Myelination of mouse axons by Schwann cells transplanted from normal and abnormal human nerves

1977 • 101 citations

Antiserum-mediated demyelination in vivo: a sequential study using intraneural injection of experimental allergic neuritis serum.

1978 • 100 citations

EFFECT OF THYROID HORMONE ON THE BIOCHEMICAL MATURATION OF RAT BRAIN: CONVERSION OF GLUCOSE‐CARBON INTO AMINO ACIDS

1970 • 99 citations

Effect of phenylalanine on protein synthesis in the developing rat brain

1970 • 99 citations

Aetiology of Multiple Sclerosis

1967 • 98 citations

Hexachlorophene encephalopathy

1973 • 97 citations

ELECTRON MICROSCOPIC OBSERVATIONS ON EXPERIMENTAL SPONGY DEGENERATION OF THE CEREBELLAR WHITE MATTER

1968 • 97 citations

Vesicular disruption of myelin in autoimmune demyelination

1975 • 95 citations

Phospholipase-A activity of mammalian tissues

1965 • 94 citations

Chemical studies of peripheral nerve during Wallerian degeneration. 4. Phosphatases

1952 • 94 citations

Somatofugal events in wallerian degeneration: A conceptual overview

1973 • 94 citations

Cell-mediated demyelination of peripheral nerve in tissue culture.

1969 • 94 citations

Experimental cyanide encephalopathy: electron microscopic observations of early lesions in white matter.

1967 • 91 citations

Effect of Demyelination on Conduction in the Central Nervous System

1969 • 89 citations

The myelopathy of pernicious anemia. A neuropathological reappraisal.

1968 • 89 citations

ALLERGIC ENCEPHALOMYELITIS INDUCED BY BRAIN ANTIGEN AFTER DEFICIENCY IN POLYUNSATURATED FATTY ACIDS DURING MYELINATION

1967 • 87 citations

EARLY POSTNATAL STARVATION CAUSES LASTING BRAIN HYPOMYELINATION

1978 • 86 citations

The Lipid-Protein Unit in Myelin

1964 • 84 citations

COPPER DEFICIENCY IN THE DEVELOPING RAT BRAIN: EVIDENCE FOR ABNORMAL MITOCHONDRIA¹

1975 • 83 citations

Hypomyelination in Copper-Deficient Rats

1976 • 83 citations

Neural Lesions in the Offspring of Female Rats Fed α Copper-deficient Diet

1969 • 83 citations

Degradation of encephalitogen by purified brain acid proteinase

1968 • 83 citations

The demonstration of recurrent demyelination and remyelination of axons in the central nervous system

1981 • 81 citations

The Effects of Spinal Cord Trauma on Myelin

1980 • 81 citations

Neuropathologic Observations in Electrolyte-induced Myelinolysis in the Rat

1982 • 81 citations

Changes in proteolytic enzymes and proteins during maturation of the brain

1975 • 78 citations

CYANIDE LEUCOENCEPHALOPATHY IN RATS AND OBSERVATIONS ON THE VASCULAR AND FERMENT HYPOTHESES OF DEMYELINATING DISEASES

1950 • 78 citations

Lead Encephalopathy in the Developing Rat: Effect Upon Myelination

1974 • 77 citations

INHIBITION OF ACETYLCHOLINE SYNTHESIS AND OF CARBOHYDRATE UTILIZATION BY MAPLE‐SYRUP‐URINE DISEASE METABOLITES

1976 • 77 citations

The effect of undernutrition on the development of myelin in the rat central nervous system

1971 • 77 citations

Mechanism of demyelination in allergic encephalomyelitis of guinea pigs. An electron microscopic study

1967 • 76 citations

STUDIES ON THE MECHANISM OF DEMYELINATION: TRIETHYL TIN-INDUCED DEMYELINATION

1973 • 76 citations

BRAIN LIPIDS, PROTEOLIPIDS, AND FREE AMINO ACIDS IN MAPLE SYRUP URINE DISEASE*

1966 • 76 citations

Tellurium neuropathy

1970 • 75 citations

Influence of Thyroid Hormones on Enzyme Activities of Myelinating Rat Central‐Nervous Tissues

1972 • 74 citations

Remyelination of the superior cerebellar peduncle in old mice following demyelination induced by cuprizone

1974 • 73 citations

A quantitative analysis of the effects of the intraneural injection of lysophosphatidyl choline

1973 • 73 citations

Lipid and Protein Alterations of Spinal Cord and Cord Myelin of Multiple Sclerosis

1982 • 72 citations

LIPID AND PROTEIN CHANGES IN SCIATIC NERVE DURING WALLERIAN DEGENERATION

1974 • 71 citations

Effects of a fatty acid deficiency on lipids of whole brain, microsomes, and myelin in the rat

1972 • 70 citations

PROTEINS, LIPID-PROTEIN DISSOCIATION AND PROTEINASE ACTIVITY IN WALLERIAN DEGENERATION

1961 • 70 citations

Tissue culture studies of demyelinating disease: A critical review

1977 • 70 citations

STUDIES ON EXPERIMENTAL ALLERGIC PERIPHERAL NEURITIS

1968 • 69 citations

QUANTITATIVE BIOCHEMICAL STUDIES OF WALLERIAN DEGENERATION IN THE PERIPHERAL AND CENTRAL NERVOUS SYSTEMS—II

1959 • 68 citations

Lysophosphatidyl choline-induced focal demyelination in the rabbit corpus callosum

1979 • 68 citations

Metabolic Instability of Myelin Proteins

1975 • 68 citations

Effect of Pre- and Postnatal Essential Fatty Acid Deficiency on Brain Development and Myelination

1979 • 68 citations

Chronic Experimental Allergic Encephalomyelitis Induced in Rabbits with Bovine White Matter Proteolipid Apoprotein

1982 • 67 citations

The effect of hexachlorophene on the respiration of brain and liver mitochondria

1972 • 66 citations

II. Microchemical and Histologic Study of Myelin Formation in the Rat

1970 • 66 citations

Lipid alterations in human brains in phenylketonuria

1967 • 65 citations

THE QUANTITATIVE HISTOCHEMISTRY OF ENZYMES OF THE PENTOSE PHOSPHATE PATHWAY IN THE CENTRAL NERVOUS SYSTEM OF THE RAT¹

1972 • 65 citations

ULTRASTRUCTURAL CHANGES IN THE REGION OF THE NODE OF RANVIER IN THE RAT CAUSED BY DIPHTHERIA TOXIN

1969 • 64 citations

Spongiform encephalopathy induced in rats and guinea pigs by cuprizone

1969 • 63 citations

Lead encephalopathy: the significance of lead inhibition of calcium uptake by brain mitochondria

1977 • 63 citations

COPPER DEFICIENCY AND THE CENTRAL NERVOUS SYSTEM

1974 • 63 citations

Development of Myelin in Inherited Disorders of Amino Acid Metabolism

1968 • 62 citations

The pathogenesis of lead encephalopathy

1980 • 61 citations

The selective release of phospholipase A2 by resident mouse peritoneal macrophages

1981 • 61 citations

Pathology of demyelination and remyelination.

1981 • 61 citations

IN VITRO DEMYELINATION OF PERIPHERAL NERVE INDUCED WITH SENSITIZED CELLS^*

1965 • 60 citations

The Sequential Alterations of Endoneurial Cholesterol and Fatty Acid in Wallerian Degeneration and Regeneration

1980 • 60 citations

Glial bridges and Schwann cell migration during chronic demyelination in the C.N.S.

1978 • 60 citations

Fat Deficiency in Rats during Development of the Central Nervous System and Susceptibility to Experimental Allergic Encephalomyelitis

1975 • 59 citations

A BIOCHEMICAL AND MORPHOLOGIC STUDY OF MYELINATION AND DEMYELINATION

1958 • 59 citations

An ultrastructural study of experimental demyelination and remyelination. V. Central and peripheral nervous system lesions caused by diphtheria toxin.

1971 • 59 citations

Myelination Inhibition Factor: Dissociation from Induction of Experimental Allergic Encephalomyelitis

1973 • 58 citations

Lipid and basic protein interaction in myelin

1974 • 58 citations

BRAIN RECOVERY FROM ESSENTIAL FATTY ACID DEFICIENCY IN DEVELOPING RATS ¹

1971 • 58 citations

IMPAIRED MYELIN FORMATION IN EXPERIMENTAL HYPERPHENY LALANINAEMIA¹

1972 • 58 citations

BIOCHEMICAL STUDIES OF MYELIN IN WALLERIAN DEGENERATION OF RAT OPTIC NERVE

1973 • 58 citations

EXPERIMENTAL DEMYELINATION BY MEANS OF ENZYMES, ESPECIALLY THE ALPHA TOXIN OF CLOSTRIDIUM WELCHII

1950 • 56 citations

Pathobiology of Acute Triethyltin Intoxication

1970 • 56 citations

Ultrastructural sequence of myelin degradation

1978 • 56 citations

Axonal Flow and Myelin Protein in the Optic Pathway

1973 • 56 citations

ACID PROTEINASE ACTIVITY OF WHITE MATTER AND PLAQUES IN MULTIPLE SCLEROSIS

1970 • 56 citations

THE CHOROID PLEXUS IN PASSIVE SERUM SICKNESS

1977 • 55 citations

MAPLE SYRUP URINE DISEASE METABOLITES STUDIED IN CEREBELLUM CULTURES¹

1969 • 54 citations

Proteinase activity of myelin

1969 • 54 citations

FINE STRUCTURAL LOCALIZATION OF CHOLESTEROL-1,2-3H IN DEGENERATING AND REGENERATING MOUSE SCIATIC NERVE

1972 • 54 citations

PATTERNS OF PERIPHERAL DEMYELINATION IN VITRO^*

1965 • 53 citations

Proteins of rat brain myelin in neonatal hypothyroidism

1975 • 53 citations

Immune Processes and Infectious Factors in Central Nervous System Disease

1969 • 53 citations

DEMYELINATION INDUCED IN MICE BY AVIRULENT SEMLIKI FOREST VIRUS. II. AN ULTRASTRUCTURAL STUDY OF FOCAL DEMYELINATION IN THE BRAIN

1982 • 53 citations

Biochemical and pathological studies of myelin in hexachlorophene intoxication

1975 • 53 citations

Lipid Composition of rat brain myelin in triethyl tin-induced edema

1971 • 53 citations

CYTOPATHIC EFFECTS OF VISNA VIRUS IN CULTURED MAMMALIAN NERVOUS TISSUE

1969 • 52 citations

SOME PROPERTIES OF A MAJOR STRUCTURAL GLYCOPROTEIN OF SCIATIC NERVE

1974 • 51 citations

Early Effects of Inorganic Lead on Immature Rat Brain Mitochondrial Respiration

1976 • 51 citations

The Role of Endoneurial Fibroblasts in Myelin Degradation

1981 • 51 citations

REMYELINATION IN RELATION TO CLINICAL LESIONS OF THE CENTRAL NERVOUS SYSTEM

1974 • 50 citations

The Endoneurial Content of Lead Related to the Onset and Severity of Segmental Demyelination

1980 • 49 citations

The breakdown of myelin-bound proteins by intra- and extracellular proteases

1976 • 48 citations

THE BINDING OF TRIETHYLTIN TO RAT BRAIN MYELIN

1975 • 48 citations

Pathogenesis of myelin lesions in experimental cyanide encephalopathy

1968 • 48 citations

Degradation of the P₀, P₁, and P_r, Proteins in Peripheral Nervous System Myelin by Plasmin: Implications Regarding the Role of Macrophages in Demyelinating Diseases

1981 • 47 citations

Isonicotinic acid hydrazide-induced spongy degeneration of the white matter in the brains of Pekin ducks.

1966 • 47 citations

Effects of a postnatal protein deficiency on the content and composition of myelin from brains of weanling rats

1975 • 47 citations

Metabolism of peripheral nerve myelin in experimental diabetes.

1975 • 47 citations

Sulfatide Synthesis: Inhibition by Experimental Allergic Encephalomyelitis Serum

1972 • 47 citations

EFFECTS OF ESSENTIAL FATTY ACID DEFICIENCY ON MYELIN AND VARIOUS SUBCELLULAR STRUCTURES IN RAT BRAIN

1972 • 45 citations

Myelination Inhibiting and Neuroelectric Blocking Factors in Experimental Allergic Encephalomyelitis

1975 • 45 citations

EFFECT OF PROTEOLYTIC ATTACK ON THE STRUCTURE OF CNS MYELIN MEMBRANE

1974 • 45 citations

EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

1971 • 45 citations

DIPHTHERIA TOXIN INHIBITS THE SYNTHESIS OF MYELIN PROTEOLIPID AND BASIC PROTEINS BY PERIPHERAL NERVE IN VITRO^1,2

1973 • 44 citations

Enzymatic degradation of myelin basic protein in central nervous system lesions of monkeys with experimental allergic encephalomyelitis.

1973 • 44 citations

Reutilization of cholesterol-1,2-H3 in the regeneration of peripheral nerve. An autoradiographic study.

1970 • 44 citations

Chemical and Morphological Changes in the Brains of Copper-deficient Guinea Pigs

1968 • 43 citations

THE EFFECTS OF PHENYLALANINE ON AMINO ACID METABOLISM AND PROTEIN SYNTHESIS IN BRAIN CELLS IN VITRO¹

1976 • 43 citations

Regeneration after nerve transection: Effect of inhibition of collagen synthesis

1974 • 43 citations

PHOSPHOLIPASE A ACTIVITIES IN NORMAL AND SECTIONED RAT SCIATIC NERVE

1973 • 43 citations

An Experimental Study of Thiamine Deficiency in Nervous Tissue, using Tissue Culture Technics

1966 • 43 citations

KINETIC ANALYSIS OF PHENYLALANINE‐INDUCED INHIBITION IN THE SATURABLE INFLUX OF TYROSINE, TRYPTOPHAN, LEUCINE AND HISTIDINE INTO BRAIN CORTEX SLICES FROM ADULT AND 7‐DAY‐OLD RATS

1975 • 42 citations

PROTEOLYTIC ENZYMES AND EXPERIMENTAL DEMYELINATION IN THE RAT AND MONKEY

1974 • 42 citations

Hexachlorophene Induced Myelin Lesions in the Developing Nervous System ofXenopusTadpoles: Morphological and Biochemical Observations

1974 • 42 citations

STUDIES OF THE MECHANISM OF DEMYELINATION REGIONAL DIFFERENCES IN MYELIN STABILITY IN VITRO

1975 • 41 citations

Peripheral Nerve Demyelination Induced by Intraneural Injection of Experimental Allergic Encephalomyelitis Serum

1979 • 41 citations

Hexachlorophene intoxication: Characterization of myelin and myelin related fractions in the rat during early postnatal development

1974 • 41 citations

MYELINATION OF RAT SCIATIC NERVE

1973 • 41 citations

Experimental cyanide encephalopathy.

1959 • 40 citations

Experimentally induced and natural recovery from the effects of phenylalanine on brain protein synthesis

1978 • 40 citations

The action of trialkyltin compounds on mitochondrial respiration. The effect of pH

1974 • 40 citations

Progress in Neuropathology, Vol 5

1983 • 39 citations

Experimental inhibition of myelination in spinal cord tissue cultures: Enzyme assays

1973 • 39 citations

Triethyltin Sulfate-Induced Neuropathy in Rats

1976 • 39 citations

Essential fatty acid deficiency and CNS myelin

1978 • 38 citations

CEREBRAL LIPID METABOLISM IN EXPERIMENTAL HYPERPHENYLALANINAEMIA: INCORPORATION OF ¹⁴C‐LABELLED GLUCOSE INTO TOTAL LIPIDS*

1970 • 38 citations

Changes in cathepsins B-1 and D, neutral proteinase and 2′,3′-cyclic nucleotide-3′-phosphohydrolase activities in monkey brain with experimental allergic encephalomyelitis

1974 • 38 citations

Some aspects of remyelination after demyelination produced by the intraneural injection of lysophosphatidyl choline

1973 • 38 citations

THE SCHWANN CELL: A REAPPRAISAL OF ITS ROLE IN THE PERIPHERAL NERVOUS SYSTEM

1978 • 38 citations

Synthesis of myelin proteins during starvation

1974 • 37 citations

STUDIES OF THE MECHANISM OF DEMYELINATION REGIONAL DIFFERENCES IN MYELIN STABILITY IN VITRO

1975 • 37 citations

Lipid synthesis in peripheral nerve from alloxan diabetic rats

1966 • 37 citations

Multiple sclerosis: vitamin D and calcium as environmental determinants of prevalence

1974 • 37 citations

Optic and Peripheral Nerve Response to Triethyltin Intoxication in the Rabbit: Biochemical and Ultrastructural Studies

1966 • 37 citations

The action of snake venom, phospholipase A and trypsin on purified myelin in vitro

1976 • 37 citations

Some new observations in triethyl-tin intoxication of rats

1971 • 36 citations

Myelination of brain in experimental hypothyroidism

1975 • 36 citations

Effects of undernutrition on glial maturation

1978 • 36 citations

Energy dependence of amino acid uptake in brain slices

1969 • 36 citations

Ultrastructural sequence of myelin degradation

1978 • 36 citations

Innervation of extrafusal and intrafusal fibres in snake muscle

1973 • 35 citations

Inhibition of a transmethylation reaction in the central nervous system-an experimental model for subacute combined degeneration of the cord.

1973 • 34 citations

Macrophages and cathepsin A activity in multiple sclerosis brain

1974 • 34 citations

Triethyltin sulfate-induced splitting of peripheral myelin in rats.

1973 • 34 citations

Treatment of experimental allergic encephalomyelitis with an inhibitor of cathepsin D (pepstatin)

1978 • 34 citations

Inhibition of sterol synthesis in vitro by metabolites of phenylalanine

1969 • 33 citations

Myelin lipophilin-induced demyelinating disease of the central nervous system

1980 • 33 citations

THE EFFECTS OF PYRIDOXINE DEFICIENCY AND OF CALORIC RESTRICTION ON LIPIDS IN THE DEVELOPING RAT BRAIN¹

1971 • 33 citations

EFFECT OF HYPERPHENYLALANINEMIA ON FATTY ACID COMPOSITION OF LIPIDS OF RAT BRAIN MYELIN

1973 • 32 citations

Hyperphenylalaninemia: effect on the developing rat brain

1969 • 32 citations

The effects of phospholipase C (Clostridium perfringens) on purified myelin

1971 • 32 citations

ACID PROTEINASES AND OTHER ACID HYDROLASES IN EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS: PINPOINTING THE SOURCE¹

1975 • 32 citations

Enzyme activities associated with the demyelinating phase of canine distemper

1972 • 32 citations

LIPID CONTENT IN BRAIN AND SPINAL CORD DURING EXPERIMENTAL ALLERGIC ENCEPHALO‐MYELITIS IN RATS¹

1972 • 31 citations

Progress in Neuropathology. Vol. III

1978 • 31 citations

The relationship between enzyme activity and neuroglia in the prodromal and demyelinating stages of cyanide encephalopathy in the rat

1963 • 31 citations

IN VITRO INCORPORATION OF [¹⁴C]‐AMINO ACIDS INTO PROTEINS OF PERIPHERAL NERVE DURING WALLERIAN DEGENERATION

1961 • 31 citations

Maple Syrup Disease

1967 • 31 citations

Myelin Proteins, Glycoproteins, and Myelin‐Related Enzymes in Experimental Demyelination of the Rabbit Optic Nerve: Sequence of Events

1981 • 30 citations

CHOLESTEROL ESTERS AND HYDROLYTIC CHOLESTEROL ESTERASE DURING WALLERIAN DEGENERATION¹

1970 • 30 citations

Effect of Malnutrition and Subsequent Rehabilitation on the Development of Mouse Brain Myelin

1981 • 30 citations

LEAD NEUROPATHY

1977 • 30 citations

Neurotoxic effects of alkyl mercury compound on myelinating cultures of mouse cerebellum

1971 • 29 citations

Presence of marchi‐positive myelinoid bodies in the spinal cord white matter of some vertebrate species

1977 • 28 citations

PHOSPHOLIPID METABOLISM IN EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS: ACTIVITY OF MITOCHONDRIAL PHOSPHOLIPASE A₂ OF RAT BRAIN TOWARDS SPECIFICALLY LABELLED 1,2‐DIACYL‐, 1‐ALK‐1′‐ENYL‐2‐ACYL‐ AND 1‐ALKYL‐2‐ACYL‐SN‐GLYCERO‐ 3‐PHOSPHORYLCHOLINE

1974 • 28 citations

DEMYELINIZATION INDUCED IN LIVING RABBITS BY MEANS OF A LIPOLYTIC ENZYME PREPARATION

1951 • 28 citations

Lysophosphatidyl choline-induced focal demyelination in the rabbit corpus callosum

1980 • 28 citations

EXPERIMENTAL MATERNAL HYPERPHENYLALANINEMTA: DISAGGREGATION OF FETAL BRAIN RIBOSOMES

1973 • 27 citations

p-Chlorophenylalanine treatment in developing rats: protein and lipids in whole brain and myelin

1974 • 27 citations

Ultrastruktur der Glia- und Axonsch�digung durch 6-Aminonicotinamid (6 An) am Sehnerv der Ratte

1973 • 27 citations

STUDIES ON THE MECHANISM OF DEMYELINATION: MYELIN AUTOLYSIS IN NORMAL AND EDEMATOUS CNS TISSUE

1977 • 27 citations

PROTEOLYTIC DIGESTION OF BOVINE BRAIN WHITE MATTER PROTEOLIPID

1975 • 27 citations

Glucose utilization in the central nervous system in the acute gliopathy due to 6-aminonicotinamide.

1981 • 26 citations

ULTRASTRUCTURAL PATHOLOGY OF AXONS AND MYELIN IN CALCIUM INDUCED MYELOPATHY

1980 • 26 citations

Myelin Deficits Produced by Early Postnatal Exposure to Inorganic Lead or Triethyltin Are Persistent

1983 • 26 citations

MYELIN BASIC PROTEIN IN FROZEN AND UNFROZEN BOVINE BRAIN: A STUDY OF AUTOLYTIC CHANGES IN SITU¹

1975 • 26 citations

Enzymic hydrolysis of myelin basic protein and other proteins in central nervous system and lymphoid tissues from normal and demyelinating rats

1976 • 26 citations

Changes in CNS myelin proteins and glycoproteins after in situ autolysis

1977 • 26 citations

Plasmalogenase and phospholipase A1, A2, and L1 activities in white matter in canine distemper virus-associated demyelinating encephalomyelitis

1980 • 25 citations

Changes in myelin following trauma of the spinal cord in monkeys.

1973 • 25 citations

Suppressive Effect of Triethyllead on Entry of Proteins into the CNS Myelin Sheath In Vitro

1980 • 25 citations

RETARDATION OF PERIPHERAL NERVE MYELINATION IN MICE TREATED WITH INHIBITORS OF CHOLESTEROL BIOSYNTHESIS

1970 • 24 citations

Relative synthesis of myelin in different brain regions of postnatally undernourished rats

1979 • 24 citations

Rhein and derivatives. In vitro stúdies on their capacity to inhibit certain proteases

1982 • 24 citations

Neutral protease activity in lymphocytes of lewis rats with acute experimental allergic encephalomyelitis

1979 • 24 citations

MYELIN METABOLISM IN VITRO IN EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS¹

1969 • 24 citations

DECOMPOSITION OF PHOSPHOLIPIDS DURING WALLERIAN DEGENERATION J. DOMONKOS

1968 • 23 citations

The activity of pure phospholipase A2 from Crotalus atrox venom on myelin and on pure phospholipids

1974 • 23 citations

HISTOCHEMISTRY OF MYELIN?XV. CHANGES IN THE MYELIN PROTEINS OF THE PERIPHERAL NERVE UNDERGOING WALLERIAN DEGENERATION?ELECTROPHORETIC AND MICRODENSITOMETRIC OBSERVATIONS

1972 • 23 citations

Proteolytic enzymes in ordinary, hyperacute, monocytic and passive transfer forms of experimental allergic encephalomyelitis

1977 • 23 citations

PHOSPHOLIPID METABOLISM IN EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS: ACTIVITY OF BRAIN PHOSPHOLIPASE A₁, TOWARDS SPECIFICALLY LABELLED GLYCEROPHOSPHOLIPIDS

1974 • 23 citations

Glucose Metabolism of Central Nervous Tissues in Rats with Experimental Allergic Encephalomyelitis

1966 • 22 citations

The influence of pH on the inhibition of oxidative phosphorylation and electron transport by triethyltin

1971 • 22 citations

Fibrinolytic Activity of Plaques and White Matter in Multiple Sclerosis

1981 • 22 citations

Decrease in Myelin Content of Rabbit Sciatic Nerve with Aging and Diabetes

1975 • 22 citations

Glycoprotein Biosynthesis in Peripheral Nervous System Myelin: Effect of Tunicamycin

1982 • 22 citations

Abnormal amino acid metabolism and brain protein synthesis during neural development

1978 • 22 citations

Myelin protein metabolism in demyelination and remyelination in the sciatic nerve

1983 • 21 citations

Enzyme activities associated with the demyelinating phase of canine distemper

1972 • 21 citations

Early Stimulation of Phosphatidylcholine Biosynthesis During Wallerian Degeneration of Rat Sciatic Nerve

1982 • 21 citations

Effects of the cholesterol biosynthesis inhibitor ay9944 on organotypic cultures ofmouse spinal cord. Retarded myelinogenesis and induction of cytoplasmic inclusions.

1975 • 21 citations

Recent Advances in the Neurobiology of Oligodendroglia

1983 • 21 citations

Ganglioside composition of peripheral nerve undergoing Wallerian degeneration

1978 • 20 citations

Ultrastructure and biochemistry of myelin after isoniazid-induced nerve degeneration in rats

1975 • 19 citations

CHEMICAL STUDIES OF PERIPHERAL NERVE DURING WALLERIAN DEGENERATION?XI.

1959 • 19 citations

Protein differences associated with the loss of myelinated axons and fibrillary gliosis in rat optic nerves following Wallerian degeneration

1975 • 18 citations

Detection of lithocholic acid in multiple sclerosis brain tissue

1970 • 18 citations

Proteolytic activity in brain and spinal cord in sensitive and resistant strains of rat and mouse subjected to experimental allergic encephalomyelitis

1974 • 18 citations

Pattern of myelin breakdown during sciatic nerve Wallerian degeneration: reversal of the order of assembly.

1980 • 18 citations

SULPHATE METABOLISM IN ACUTE EAE¹ RATS USING ISOLATED BRAIN PERFUSION TECHNIQUE

1971 • 18 citations

Non-osmotic swelling in purified bovine myelin

1973 • 17 citations

ISOLATION AND CHARACTERIZATION OF THE INFLAMMATORY INFILTRATE IN THE CENTRAL NERVOUS SYSTEM OF THE GUINEA‐PIG WITH EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

1980 • 17 citations

How do axons control myelin formation?

1978 • 17 citations

INCORPORATION OF [¹⁴C]GLYCINE INTO PROTEIN OF THE ADULT RAT PERIPHERAL NERVE: EFFECTS OF INHIBITORS

1968 • 17 citations

The effects of trypsin on purified myelin

1973 • 17 citations

A quantitative histochemical study of early cellular events associated with destruction of myelinated axons in rat optic nerve

1974 • 17 citations

Selective loss of myelin proteins during autolysis

1977 • 17 citations

ARYLSULPHATASE A (EC 3.1.6.1) ACTIVITY IN RAT CENTRAL NERVOUS SYSTEM DURING EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

1973 • 17 citations

ATPase activity, sodium and potassium content in guinea pig cortex after ouabain treatment in vivo

1973 • 16 citations

EXPERIMENTAL STUDY OF DIPHTHERITIC POLYNEURITIS IN THE RABBIT AND GUINEA PIG

1960 • 16 citations

Amino Acid and Protein Metabolism in Wallerian Degeneration

1972 • 16 citations

A comparison of starvation models in studies of brain myelination

1979 • 15 citations

Decrease in myelin content of rabbit sciatic nerve with aging and diabetes

1975 • 15 citations

METABOLIC ACTIVITY OF CNS PROTEINS IN RATS AND MONKEYS WITH EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS (EAE)

1974 • 14 citations

QUANTITATIVE LYSOSOMAL ENZYME ACTIVITY CHANGES IN THE NEURAL LOBE OF THE RAT FOLLOWING WATER DEPRIVATION AND LACTATION

1974 • 14 citations

INCORPORATION OF ¹⁴C FROM [U‐¹⁴C]GLUCOSE INTO FREE AMINO ACIDS IN MOUSE BRAIN REGIONS UNDER CYANIDE INTOXICATION

1974 • 14 citations

Triethyl tin does not induce intramyelinic vacuoles in the CNS of the quaking mouse

1981 • 14 citations

Effects of ceramide analogs on myelinating organ cultures

1976 • 14 citations

Intracerebrally injected monohydroxy and other C₂₄ steroid acids as demyelinating agents in the guinea pig

1970 • 14 citations

2′, 3′-Cyclic nucleotide 3′-phosphohydrolase activity in brain of acute experimental allergic encephalomyelitis

1979 • 14 citations

Comparative Histologic and Electron Microscope Investigations of the Central Nervous System

1956 • 14 citations

Maternal deficiency of protein or protein and calories during lactation: Effect upon CNS myelin subfraction formation in rat offspring

1978 • 13 citations

A possible block in the intermediary metabolism of glucose into proteins and lipids in the brains of undernourished rats

1971 • 13 citations

STABILITY OF THE BRAIN FATTY ACID PATTERN IN ADULT RATS DURING EXTREME STARVATION¹

1974 • 13 citations

In vitro inhibition of brain metabolism during postnatal development by high levels of phenylalanine and tryptophan

1969 • 12 citations

A comparison of brain lysosomal enzyme activities in four experimental togavirus encephalitides

1978 • 12 citations

EFFECT OF ACUTE CYANIDE INTOXICATION ON THE ACTIVE TRANSPORT OF AMINO ACIDS IN BRAIN SLICES*

1968 • 12 citations

Partial purification and characterization of neutral proteases in lymph nodes of rats with experimental allergic encephalomyelitis

1981 • 12 citations

Protein composition of forebrain myelin isolated from triethyllead‐intoxicated young rats

1978 • 12 citations

Proteolytic and peroxidatic reactions of commercial horseradish peroxidase with myelin basic protein

1978 • 12 citations

Changes in Metabolic Processes During Pathogenesis of Experimental Allergic Encephalomyelitis

1972 • 12 citations

Cholic acid as a demyelinating agent in vivo

1964 • 12 citations

Ultrastructural and biochemical studies on ouabain-induced oedematous brain

1977 • 11 citations

Schwann Cell Surface Proteins and Glycoproteins

1982 • 10 citations

Peripheral Nerve Phospholipid Composition: Development in Normal Nerve and Age‐Dependent Changes in Wallerian Degenerated Nerve

1982 • 10 citations

Effect of triethyllead on post-translational processing of myelin proteins

1982 • 10 citations

Adjuvanticity of Synthetic Polynucleotides for Induction of Experimental Allergic Encephalomyelitis in Guinea Pigs

1974 • 9 citations

Incorporation of fucose and leucine into PNS myelin proteins in nerves undergoing early Wallerian degeneration

1981 • 9 citations

SOME REMARKS ON THE PATHOGENESIS OF DEMYELINATING DISEASES

1963 • 9 citations

Demyelination

1982 • 9 citations

THE EFFECTS OF PHENYLKETONURIC AND OTHER METABOLITES ON SULFATED GALACTOCEREBROSIDE SYNTHESIS IN VIVO AND IN CULTURE

1976 • 9 citations

BIOSYNTHESIS AND COMPOSITION OF BRAIN GALACTOLIPIDS IN NORMAL AND HYPOTHYROID RATS

1973 • 8 citations

Alterations of lipid and protein composition in myelin of acute experimental allergic neuritis

1980 • 8 citations

Synthesis of myelin, particulate, and soluble protein subfractions of rat sciatic nerve during the early stage of Wallerian degeneration: A comparison of metabolic studies using double and single isotope methods and recovery

1982 • 8 citations

Myelin and Microsomes from Rhesus Monkey Spinal Cord: Isolation and Effects of Trauma

1980 • 8 citations

ANTI‐WHOLE WHITE MATTER SERUM INHIBITS INCORPORATION OF GLUCOSE AND GALACTOSE INTO THE LIPIDS OF MYELINATING SPINAL CORD CULTURES

1978 • 8 citations

The effect of 6-aminonicotinamide on the levels of brain amino acids and glucose, and their labeling with14C after injection of [U-14C] glucose

1981 • 8 citations

Histochemistry of the neuroglia and myelin in experimental cerebral oedema

1965 • 8 citations

Suppression of experimental allergic encephalomyelitis in guinea-pigs with poly-L-lysine.

1975 • 8 citations

Essential Fatty Acid Deficiency and Its Effects on the Central Nervous System

1971 • 7 citations

Protein synthesis in experimental allergic encephalo-myelitis

1974 • 6 citations

CELL-FREE PROTEIN SYNTHESIS BY RAT BRAIN IN TRIETHYL TIN INTOXICATION

2009 • 6 citations

CNS myelin‐associated glycoproteins in the offspring of protein deficient rats

1979 • 5 citations

2′,3′‐Cyclic nucleotide 3′‐phosphohydrolase activity of the central nervous tissue in experimental allergic encephalomyelitis

1972 • 5 citations

ACTIVATION OF AMINO ACIDS IN THE BRAIN DURING EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS

1971 • 5 citations

The reaction of myelin phospholipids with phospholipase C and D

1975 • 4 citations

Effects of anti-white matter serum on myelin and lipid synthesis in brain prisms

1979 • 4 citations

Central nervous system electrolyte pattern in allergic encephalomyelitis

1961 • 4 citations

Demyelinating Cholinesterase Inhibitors: Lipid and Protein Metabolism

1971 • 4 citations

Alteration of fucose/leucine incorporation into PNS myelin by isoniazid neuropathy

1981 • 4 citations

Effect of triethyltin on Escherichia coli K-12

1977 • 4 citations

Demyelinating pattern of experimental allergic peripheral neuritis, studied in vitro.

1969 • 3 citations

Effect of neonatal thyroidectomy on glycolipid metabolism in developing rat brain.

1972 • 3 citations

In Memoriam

1969 • 2 citations

Myelin lipids in experimental allergic encephalomyelitis.

1975 • 1 citations

Protein synthesis in vitro by the rat brain in course of experimental cyanide encephalopathy.

1974 • 1 citations

Deleted Work

1955 • 0 citations