Experimentally induced and natural recovery from the effects of phenylalanine on brain protein synthesis

The Metabolic Basis of Inherited Disease.

1972 • 1,407 citations

Improved separation of transfer RNA's on polychlorotrifluoroethylene-supported reversed-phase chromatography columns

1971 • 504 citations

Protein Metabolism of The Nervous System

1964 • 275 citations

Initiation of hemoglobin synthesis. Specific inhibition by antibiotics and bacteriophage ribonucleic acid

1971 • 183 citations

Protein Synthesis in Rat Liver: Influence of Amino Acids in Diet on Microsomes and Polysomes

1965 • 177 citations

Regulation of polysome aggregation in a cell-free system through ammo acid supply

1968 • 163 citations

THE INFLUENCE OF HIGH PHENYLALANINE AND TYROSINE ON THE CONCENTRATIONS OF ESSENTIAL AMINO ACIDS IN BRAIN

1968 • 163 citations

Influence of amino acid supply on ribosomes and protein synthesis of perfused rat liver

1969 • 143 citations

Hyperphenylalaninemia: Disaggregation of Brain Polyribosomes in Young Rats

1970 • 131 citations

Heritable Disorders of Amino Acid Metabolism: Patterns of Clinical Expression and Genetic Variation.

1975 • 102 citations

Comparison of the effect of amino acid supply on hepatic polysome profiles in vivo and in vitro

1968 • 84 citations

EVIDENCE FOR SEPARATE SYSTEMS FOR THE TRANSPORT OF NEUTRAL AND BASIC AMINO ACIDS ACROSS THE BLOOD‐BRAIN BARRIER

1971 • 84 citations

POLYRIBOSOME DISAGGREGATION AND CELL‐FREE PROTEIN SYNTHESIS IN PREPARATIONS FROM CEREBRAL CORTEX OF HYPERPHENYLALANINEMIC RATS¹

1971 • 72 citations

INHIBITION OF BRAIN PROTEIN SYNTHESIS: AN APPROACH TO THE BIOCHEMICAL BASIS OF NEUROLOGICAL DYSFUNCTION IN THE AMINO‐ACIDURIAS*,†

1966 • 62 citations

CELL‐FREE PROTEIN SYNTHESIS BY MOUSE BRAIN DURING EARLY DEVELOPMENT

1968 • 60 citations

The mechanism of polyribosome disaggregation in brain tissue by phenylalanine

1975 • 60 citations

Inhibition of initiation of protein synthesis in mammalian tissue culture cells by L-1-tosylamido-2-phenylethyl chloromethyl ketone.

1975 • 55 citations

Effects of excess phenylalanine onin vitro andin vivo RNA and protein synthesis and polyribosome levels in brains of mice

1971 • 53 citations

Cerebral proteolipids in phenylketonuria

1968 • 48 citations

THE EFFECTS OF PHENYLALANINE ON AMINO ACID METABOLISM AND PROTEIN SYNTHESIS IN BRAIN CELLS IN VITRO¹

1976 • 43 citations

The effects of hyperphenylalaninaemia on the concentrations of aminoacyl-transfer ribonucleic acid in vivo. A mechanism for the inhibition of neural protein synthesis by phenylalanine

1977 • 41 citations

THE INFLUENCE OF EXCESS METHIONINE ON THE FREE AMINO ACIDS OF BRAIN AND LIVER OF THE WEANLING RAT*

1969 • 41 citations

ELEVATED PLASMA PHENYLALANINE CONCENTRATION AND LYSINE INCORPORATION INTO RIBOSOMAL PROTEIN OF DEVELOPING BRAIN

1968 • 39 citations

Effect of Amino Acids on Ribosome Aggregation and Protein Synthesis in Perfused Rat Liver

1973 • 37 citations

INCORPORATION OF PHENYLALANINE, TYROSINE AND TRYPTOPHAN INTO PROTEIN OF HOMOGENATES FROM DEVELOPING RAT BRAIN: KINETICS OF INCORPORATION AND RECIPROCAL INHIBITION

1972 • 30 citations

Hyperphenylalanemia: Effect on Brain Polyribosomes Can Be Partially Reversed by Other Amino Acids

1977 • 18 citations