5‐Hydroxytryptamine, substance P, and thyrotropin‐releasing hormone in the adult cat spinal cord segment L7: Immunohistochemical and chemical studies
Data up to Jan 2025
Total Citations Per Year
Abstract
References (177)
EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS.
1964 • 5,110 citations
Estimation of nuclear population from microtome sections
1946 • 4,378 citations
Distribution of serotonin-immunoreactivity in the central nervous system of the rat—Cell bodies and terminals
1981 • 2,392 citations
A simple method of reducing the fading of immunofluorescence during microscopy
1981 • 1,907 citations
General Cytochemical Methods
1961 • 1,630 citations
The cytoarchitectonic organization of the spinal cord in the cat
1952 • 1,595 citations
Flexion‐reflex of the limb, crossed extension‐reflex, and reflex stepping and standing
1910 • 1,288 citations
Cholinergic and inhibitory synapses in a pathway from motor‐axon collaterals to motoneurones
1954 • 1,172 citations
Experimental immunohistochemical studies on the localization and distribution of substance P in cat primary sensory neurons
1975 • 1,073 citations
Calcitonin gene-related peptide immunoreactivity in the spinal cord of man and of eight other species
1984 • 1,024 citations
EVIDENCE FOR THE EXISTENCE OF MONOAMINE NEURONS IN THE CENTRAL NERVOUS SYSTEM. II. EXPERIMENTALLY INDUCED CHANGES IN THE INTRANEURONAL AMINE LEVELS OF BULBOSPINAL NEURON SYSTEMS.
1965 • 1,004 citations
Immunohistochemical evidence of substance P-like immunoreactivity in some 5-hydroxytryptamine-containing neurons in the rat central nervous system
1978 • 809 citations
Buffered picric acidformaldehyde: A new rapid fixative for electron microscopy
1967 • 784 citations
The distribution of substance P immunoreactive fibers in the rat central nervous system
1978 • 725 citations
Bistability of alpha‐motoneurones in the decerebrate cat and in the acute spinal cat after intravenous 5‐hydroxytryptophan.
1988 • 704 citations
The convergence of monosynaptic excitatory afferents on to many different species of alpha motoneurones
1957 • 701 citations
Immunohistochemical support for three putative transmitters in one neuron: Coexistence of 5-hydroxytryptamine, substance p- and thyrotropin releasing hormone-like immunoreactivity in medullary neurons projecting to the spinal cord
1981 • 698 citations
Detection of substance P in the central nervous system by a monoclonal antibody.
1979 • 594 citations
Progress in Brain Research
1969 • 591 citations
Immunoreactive calcitonin gene-related peptide and substance P coexist in sensory neurons to the spinal cord and interact in spinal behavioral responses of the rat
1984 • 573 citations
Coexistence of peptides and classical neurotransmitters
1983 • 559 citations
Retardation of fading and enhancement of intensity of immunofluorescence by p-phenylenediamine.
1983 • 544 citations
Localization of serotonin in the central nervous system by immunohistochemistry: Description of a specific and sensitive technique and some applications
1978 • 535 citations
Cellular Localization of Monoamines in the Spinal Cord
1964 • 528 citations
The motor cell columns of the lumbo‐sacral spinal cord of the cat
1951 • 526 citations
Coexistence of galanin-like immunoreactivity with catecholamines, 5- hydroxytryptamine, GABA and neuropeptides in the rat CNS
1986 • 520 citations
Neural peptides and neuronal communication.
1980 • 518 citations
The origin, distribution and synaptic relationships of substance P axons in rat spinal cord
1979 • 489 citations
Facilitation of spinal motoneurone excitability by 5-hydroxytryptamine and noradrenaline
1980 • 485 citations
Serotonin and substance P coexist in neurons of the rat's central nervous system
1978 • 483 citations
Regional distribution of substance P in the spinal cord and nerve roots of the cat and the effect of dorsal root section
1975 • 443 citations
Serotonergic facilitation of facial motoneuron excitation
1979 • 440 citations
CENTRAL EFFECTS OF CENTRIPETAL IMPULSES IN AXONS OF SPINAL VENTRAL ROOTS
1946 • 434 citations
Brain Stem Control of Spinal Mechanisms
1982 • 424 citations
The Use of Dopamine β-Hydroxylase as a Marker for the Central Noradrenergic Nervous System in Rat Brain
1972 • 416 citations
The Distribution of Adrenergic Nerve Fibres to the Blood Vessels in Skeletal Muscle
1965 • 412 citations
Topographic principles in the spinal projections of serotonergic and non-serotonergic brainstem neurons in the rat
1985 • 411 citations
The vestibulospinal tract. Effects on alpha-motoneurones in the lumbosacral spinal cord in the cat
1970 • 408 citations
Brainstem projections to spinal motoneurons: An update
1987 • 388 citations
A Quantitative Study on the Nigro‐Neostriatal Dopamine Neuron System in the Rat
1966 • 374 citations
Descending serotonergic, peptidergic and cholinergic pathways from the raphe nuclei: A multiple transmitter complex
1983 • 370 citations
Fluorescent Protein Tracing
1969 • 364 citations
NEURON PATTERNS CONTROLLING TRANSMISSION OF IPSILATERAL HIND LIMB REFLEXES IN CAT
1943 • 352 citations
Monoamine cell distribution in the cat brain stem. A fluorescence histochemical study with quantification of indolaminergic and locus coeruleus cell groups
1981 • 329 citations
A laminar analysis of the number of neurons, glia, and synapses in the visual cortex (area 17) of adult macaque monkeys
1982 • 328 citations
Coexistence of peptides with classical neurotransmitters
1987 • 327 citations
Serotonergic and peptidergic projections to the spinal cord demonstrated by a combined retrograde HRP histochemical and immunocytochemical staining method
1981 • 266 citations
Immunoreactive substance P and serotonin present in the same dense-core vesicles
1981 • 265 citations
Evidence for differential localization of noradrenaline and neuropeptide Y in neuronal storage vesicles isolated from rat vas deferens
1985 • 261 citations
Characterization of an immunofluorescence technique for the demonstration of coexisting neurotransmitters within nerve fibers and terminals.
1985 • 247 citations
The density of synapses and neurones in the motor and visual areas of the cerebral cortex.
1967 • 240 citations
Immunohistochemical demonstration of the distribution of serotonin neurons in the brainstem of the rat and cat
1982 • 239 citations
On the function of recurrent inhibition in the spinal cord
1979 • 237 citations
The effects of monoamine neurotoxins on peptides in the rat spinal cord
1982 • 234 citations
Thyrotropin releasing hormone (TRH)-containing nerve terminals in certain brain stem nuclei and in the spinal cord
1975 • 234 citations
Use of high concentrations of glutaraldehyde for immunocytochemistry of transmitter-synthesizing enzymes in the central nervous system
1986 • 233 citations
Plateau potentials in alpha‐motoneurones induced by intravenous injection of L‐dopa and clonidine in the spinal cat.
1988 • 229 citations
Similar motor effects of 5-HT and TRH in rats following chronic spinal transection and 5,7-dihydroxytryptamine injection
1981 • 227 citations
The effects of dorsal rhizotomy and spinal cord isolation on calcitonin gene-related peptide-labeled terminals in the rat lumbar dorsal horn
1988 • 224 citations
Relative contribution from different nerves to recurrent depression of Ia IPSPs in motoneurones
1971 • 223 citations
A quantitative light microscopic study of the dendrites of cat spinal γ‐motoneurons after intracellular staining with horseradish peroxidase
1981 • 210 citations
Effects of 5-hydroxytryptamine on the afterhyperpolarization, spike frequency regulation, and oscillatory membrane properties in lamprey spinal cord neurons
1989 • 205 citations
Substance P neurons project from the ventral medulla to the intermediolateral cell column and ventral horn in the rat
1982 • 199 citations
Maintained changes in motoneuronal excitability by short‐lasting synaptic inputs in the decerebrate cat.
1988 • 196 citations
Serotonin neurons in nucleus raphe dorsalis and paragigantocellularis of the cat contain enkephalin.
1981 • 180 citations
The topographical distribution of serotoninergic terminals in the spinal cord of the cat: biochemical mapping by the combined use of microdissection and microassay procedures
1977 • 178 citations
The rubrospinal tract. I. Effects on alpha-motoneurones innervating hindlimb muscles in cats
1969 • 178 citations
A quantitative light microscopic study of the dendrites of cat spinal α-motoneurons after intracellular staining with horseradish peroxidase
1981 • 168 citations
Coerulospinal influence on recurrent inhibition of spinal motonuclei innervating antagonistic hindleg muscles of the cat
1988 • 166 citations
Immunocytochemical analysis of serotonergic axons in laminae I and II of the lumbar spinal cord of the cat
1982 • 158 citations
Suppression of the recurrent inhibitory pathway in lumbar cord segments during locus coeruleus stimulation in cats
1987 • 157 citations
Combined light and electron microscopic tracing of neurons, including axons and synaptic terminals, after intracellular injection of horseradish peroxidase
1976 • 155 citations
Serotonin; From cell biology to pharmacology and therapeutics
1991 • 153 citations
Effect of chronic transection on dopamine, noradrenaline and 5-hydroxytryptamine in the rat spinal cord
1973 • 148 citations
THE MODIFICATION OF LUMBAR MOTONEURONE EXCITABILITY BY STIMULATION OF A PUTATIVE 5‐HYDROXYTRYPTAMINE PATHWAY
1974 • 139 citations
Neuron size and neuron population density in the lumbosacral region of the cat's spinal cord.
1961 • 135 citations
Involvement of serotonin in the excitation of phrenic motoneurons evoked by stimulation of the raphe obscurus
1986 • 134 citations
Atlas of serotonergic cell bodies in the cat brainstem: An immunocytochemical analysis
1984 • 126 citations
Co-occurrence of substance P-like and Leu-enkephalin-like immunoreactivities in neurones and fibres of avian nervous system
1982 • 126 citations
An alternative fixation-processing method for preembedding ultrastructural immunocytochemistry of cytoplasmic antigens: the GBS (glutaraldehyde-borohydride-saponin) procedure.
1983 • 126 citations
Pharmacological antagonism of facilitatory but not inhibitory effects of serotonin and norepinephrine on excitability of spinal motoneurons
1983 • 125 citations
The distribution of serotonin, met-enkephalin and β-lipotropin-like immunoreactivity in neuronal perikarya of the cat brainstem
1982 • 121 citations
Criteria of reliability for light microscopic immunocytochemical staining
1980 • 120 citations
5-Hydroxytryptamine (serotonin) causes a reduction in the afterhyperpolarization following the action potential in lamprey motoneurons and premotor interneurons
1986 • 118 citations
Recovery of substance P in the cat spinal cord after unilateral lumbosacral deafferentation
1980 • 116 citations
Specificity in immunocytochemical staining.
1976 • 115 citations
The monoamine-containing neurons in the brain of the garfish, Lepisosteus osseus
1982 • 112 citations
A morphological study of the axons and recurrent axon collaterals of cat alpha‐motoneurones supplying different hind‐limb muscles.
1978 • 110 citations
Immunohistochemical demonstration of some putative neurotransmitters in the lamprey spinal cord and spinal ganglia: 5‐hydroxytryptamine‐, tachykinin‐, and neuropeptide‐Y‐immunoreactive neurons and fibers
1985 • 109 citations
Postnatal development of cat hind limb motoneurons. III: Changes in size of motoneurons supplying the triceps surae muscle
1988 • 107 citations
An ultrastructural study of 5-hydroxytryptamine-, thyrotropin-releasing hormone- and substance P-immunoreactive axonal boutons in the motor nucleus of spinal cord segments L7-S1 in the adult cat
1987 • 106 citations
Thyrotropin-releasing hormone in spinal cord: coexistence with serotonin and with substance P in fibers and terminals apposing identified preganglionic sympathetic neurons
1987 • 105 citations
Three-color immunofluorescence histochemistry allowing triple labeling within a single section.
1988 • 104 citations
Immunohistochemical evidence of indolamine neurons in monkey spinal cord
1982 • 104 citations
The morphology and distribution of rat serotoninergic intraspinal neurons: An immunohistochemical study
1988 • 102 citations
The coexistence of serotonin- and substance P-like immunoreactivity in the spinal cord of the rat as shown by immunofluorescent double labeling.
1987 • 100 citations
Fidia Research Foundation neuroscience award lectures
1987 • 99 citations
Human spinal neurons: Innervation by both substance p and enkephalin
1981 • 98 citations
A method for specific transmitter identification of retrogradely labeled neurons: Immunofluorescence combined with fluorescence tracing
1984 • 97 citations
A morphological study of the axons and recurrent axon collaterals of cat alpha‐motoneurones supplying different functional types of muscle unit.
1978 • 97 citations
Effects of sciatic nerve resection on L7 spinal roots and dorsal root ganglia in adult cats☆
1983 • 96 citations
Evidence for 5-hydroxytryptamine, substance P, and thyrotropin- releasing hormone in neurons innervating the phrenic motor nucleus
1984 • 95 citations
Substance P, but not TRH, modulates the 5-HT autoreceptor in ventral lumbar spinal cord
1981 • 93 citations
The effect of serotonin precursors on alpha- and gamma-motoneuron activity.
1978 • 92 citations
Ultrastructural localization of TRH-like immunoreactivity
1980 • 92 citations
Distribution of sympathetic preganglionic neurons and monoaminergic nerve terminals in the spinal cord of the rat
1989 • 91 citations
The noradrenergic neurotoxin DSP-4 eliminates the coeruleospinal projection but spares projections of the A5 and A7 groups to the ventral horn of the rat spinal cord
1989 • 90 citations
Spinal neurons mediate return of substance P following deafferentation of cat spinal cord
1981 • 90 citations
Subcellular fractionation of cat submandibular gland: Comparative studies on the distribution of acetylcholine and vasoactive intestinal polypeptide (VIP)
1981 • 89 citations
Differential release of coexisting neurotransmitters: frequency dependence of the efflux of substance P, thyrotropin releasing hormone and [3H]serotonin from tissue slices of rat ventral spinal cord
1989 • 89 citations
Spinal cord serotonin: A biochemical and immunohistochemical study following transection
1984 • 87 citations
Survey of distribution of substance P, vasoactive intestinal polypeptide, cholecystokinin, neurotensin, Met-enkephalin, bombesin and PHI in the spinal cord of cat, dog, sloth and monkey
1988 • 86 citations
Distribution of enkephalin-immunoreactive cell bodies in relation to serotonin-containing neurons in the raphe nuclei of the cat: Immunohistochemical evidence for the coexistence of enkephalins and serotonin in certain cells
1986 • 84 citations
Thyrotropin-releasing hormone-immunoreactive neurons project from the ventral medulla to the intermediolateral cell column: Partial coexistence with serotonin
1986 • 83 citations
Substance P-immunoreactive and serotonin-containing neurones in the ventral brainstem of the cat
1983 • 81 citations
An ultrastructural study of the synaptic contacts of α-motoneurone axon collaterals. I. Contacts in lamina IX and with identified α-motoneurone dendrites in lamina VII
1981 • 80 citations
The human spinal cord: substance P and methionine-enkephalin immunoreactivity
1982 • 79 citations
The human spinal cord: substance P and methionine-enkephalin immunoreactivity.
1982 • 79 citations
Immunohistochemical demonstration of serotonin neurons in autonomic regions of the rat spinal cord
1986 • 78 citations
Quantified regional and laminar distribution of the serotonin innervation in the anterior half of adult rat cerebral cortex.
1989 • 75 citations
Axon classes and internodal growth in the ventral spinal root L7 of adult and developing cats.
1988 • 73 citations
Immunocytochemical Localization of Noradrenaline, Adrenaline and Serotonin
1983 • 73 citations
The Ultrastructure and Synaptic Connections of Serotonin-Immunoreactive Terminals in Spinal Laminae I and II
1983 • 72 citations
Increase in endogenous 5-hydroxytryptamine levels modulates the central network underlying locomotion in the lamprey spinal cord
1989 • 72 citations
Lumbar dorsal root ganglia of the cat: A quantitative study of peptide immunoreactivity and cell size
1989 • 68 citations
Topographic organization of substance p and monoamine cells in the ventral medulla of the cat
1985 • 67 citations
Altered levels of calcitonin gene-related peptide (CGRP)-like immunoreactivity of cat lumbar motoneurons after chronic spinal cord transection
1989 • 66 citations
Thyrotropin releasing hormone (TRH)-immunoreactive cell groups in the rat central nervous system
1987 • 65 citations
Individual cells in the raphe nuclei of the medulla oblongata in rat that contain immunoreactivities for both serotonin and enkephalin project to the spinal cord
1989 • 63 citations
Immunohistochemical study on the distribution of serotonin fibers in the spinal cord of the dog
1982 • 61 citations
The topographical distribution of serotoninergic terminals in the spinal cord of the cat: Quantitative radioautographic studies
1978 • 60 citations
Reduction of substance P levels in the ventral cervical spinal cord of the rat after intracisternal 5, 7-dihydroxytryptamine injection
1979 • 60 citations
Recovery of substance P but not somatostatin in the cat spinal cord after unilateral lumbosacral dorsal rhizotomy: A quantitative study
1984 • 60 citations
Distribution of serotonergic neurons and processes in the lamprey spinal cord
1985 • 57 citations
The organization of serotonin fibers in the anterior column of the mammalian spinal cord
1983 • 57 citations
Coexistence of serotonin- and substance P-like immunoreactivity in nerve fibers apposing identified sympathoadrenal preganglionic neurons in rat intermediolateral cell column
1986 • 56 citations
THE DISTRIBUTION OF 5‐HYDROXYTRYPT‐AMINE and NOREPINEPHRINE IN CATSPINAL CORD *
1966 • 56 citations
Immunohistochemistry
2002 • 52 citations
Thyrotropin-releasing hormone. Biomedical significance.
1989 • 51 citations
Tryptophan hydroxylase and serotonin in spinal cord and brain stem before and after chronic transection
1971 • 51 citations
Immunohistochemical distribution of serotonin in spinal autonomic nuclei: I. Fiber patterns in the adult rat
1989 • 51 citations
On the possible existence of a new intraneuronal monoamine in the spinal cord of the rat.
1970 • 51 citations
A thyrotropin-releasing hormone-containing system in the rat dorsal horn separate from serotonin
1986 • 51 citations
Quantitative morphological changes in some spinal cord segments during postnatal development. A study in the cat.
1969 • 49 citations
Immunohistochemical localization of seven different peptides in the human spinal cord
1989 • 47 citations
The responses of motoneurones to 5-hydroxytryptamine
1980 • 46 citations
The morphological relationships between substance P immunoreactive processes and ventral horn neurons in the human and monkey spinal cord
1982 • 44 citations
Immunocytochemical identification of axons containing coexistent serotonin and substance P in the cat lumbar spinal cord
1988 • 43 citations
Neuropeptide and serotonin immunoreactive neurons in the cat ventrolateral medulla
1988 • 41 citations
Distribution of axons exhibiting both enkephalin- and serotonin-like immunoreactivities in the lumbar cord segments: an immunohistochemical study in the cat
1988 • 41 citations
Immunohistochemical studies on the distribution and origin of candidate peptidergic primary afferent neurotransmitters in the spinal cord of an elasmobranch fish, the atlantic stingray (Dasyatis sabina)
1983 • 41 citations
Serotonin and co-localized peptides: Effects on spinal motoneuron excitability
1985 • 40 citations
Regional Distribution of Immunoreactive‐Thyrotrophin‐Releasing Hormone and Substance P, and Indoleamines in Human Spinal Cord
1986 • 40 citations
Serotonergic and peptidergic inputs to the primate ventral spinal cord as visualized with multiple chromagens on the same tissue section
1986 • 40 citations
Inhibitory effects of dorsal horn and excitant effects of ventral horn intraspinal microinjections of norepinephrine and serotonin in the cat
1981 • 40 citations
Potentiation of motoneurone excitability by combined administration of 5-HT agonist and TRH analogue
1985 • 39 citations
Visualization of serotonin neurones in the nodose ganglia of the cat. An autoradiographic study
1981 • 36 citations
Colocalization of Peptide Histidine Isoleucine Amine and Corticotropin-Releasing Factor Immunoreactivity in Neurons of the Rat Hypothalamus: A Surprising Artefact
1986 • 36 citations
Intracellular studies on the effects of systemic administration of serotonin agonists on rat facial motoneurons
1982 • 36 citations
Biochemical and immunohistochemical determination of 5-hydroxytryptamine located in mast cells in the trigeminal ganglion of the rat and guinea pig
1984 • 34 citations
Demonstration of thyrotropin-releasing hormone immunoreactivity in neurons of the mouse spinal dorsal horn
1986 • 34 citations
Substance P and 5-hydroxytryptamine immunoreactive presynaptic boutons on presumed .ALPHA.-motoneurons in the chicken ventral horn.
1985 • 33 citations
Ultrastructural localization of substance P immunoreactivity in the ventral horn of the rat spinal cord
1982 • 32 citations
Evidence for colocalization of substance P and 5-hydroxytryptamine in spinally projecting neurons from the cat medulla oblongata
1989 • 32 citations
Storage of monoamines in mast cells of normal and sectioned peripheral nerve
1965 • 30 citations
Contransmitters: differential effects of serotonin (5-HT)-depleting drugs on levels of 5-HT and TRH and their receptors in rat brain and spinal cord
1989 • 30 citations
Regional Distribution of Substance P- and Thyrotrophin-Releasing Hormone-Like Immunoreactivity and Indoleamines in the Rabbit Spinal Cord
1987 • 28 citations
Evidence for differential storage of calcitonin gene-related peptide, substance P and serotonin in synaptosomal vesicles of rat spinal cord
1989 • 27 citations
Thyrotropin-releasing hormone (TRH)-immunoreactive boutons and nerve cell bodies in the dorsal horn of the cat L7 spinal cord
1987 • 27 citations
Localization of 5-hydroxytryptamine to neurons and endoneurial mast cells in rat sensory ganglia
1985 • 21 citations
Intrinsic 5HT-immunoreactive neurons in the spinal cord of the fetal non-human primate
1986 • 20 citations
Differential innervation of specific motor neuron pools by serotoninergic fibers in the chick spinal cord
1988 • 19 citations
Segmental analysis of spinal cord monoamines after thoracic transection in the dog
1975 • 17 citations
Coexistence of neuroactive substances as revealed by immunohistochemistry with monoclonal antibodies
1982 • 17 citations
Serotoninergic fibers in dorsal roots of the spinal cord
1983 • 17 citations
Measurement of catecholamines, indoleamines, thyrotrophin releasing hormone and substance P in rat and human spinal cord using a common extraction method
1987 • 9 citations
Influence of the Noradrenergic Coeruleospinal System on Recurrent Inhibition in the Spinal Cord and its Role During Postural Reflexes
1988 • 2 citations