Localization of serotonin in the central nervous system by immunohistochemistry: Description of a specific and sensitive technique and some applications

EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS.

1964 • 5,110 citations

Stereotaxic Mapping of the Monoamine Pathways in the Rat Brain*

1971 • 3,816 citations

FLUORESCENCE OF CATECHOL AMINES AND RELATED COMPOUNDS CONDENSED WITH FORMALDEHYDE

1962 • 2,684 citations

General Cytochemical Methods

1961 • 1,630 citations

Fluorescent Antibody Methods

1969 • 1,549 citations

EVIDENCE FOR THE EXISTENCE OF MONOAMINE NEURONS IN THE CENTRAL NERVOUS SYSTEM. IV. DISTRIBUTION OF MONOAMINE NERVE TERMINALS IN THE CENTRAL NERVOUS SYSTEM.

1965 • 1,543 citations

Evidence for the existence of monoamine neurons in the central nervous system

1965 • 1,538 citations

Ascending Monoamine Neurons to the Telencephalon and Diencephalon

1966 • 1,205 citations

Advances in biochemical psychopharmacology

1970 • 1,186 citations

Cellular localization of brain monoamines.

1962 • 1,141 citations

The Specificity of Serological Reactions

1945 • 1,104 citations

Identification and assay of serotonin in brain.

1956 • 850 citations

Immunohistochemical evidence of substance P-like immunoreactivity in some 5-hydroxytryptamine-containing neurons in the rat central nervous system

1978 • 809 citations

Fluorescent Protein Tracing

1965 • 708 citations

The distribution of substance P and 5‐hydroxytryptamine in the central nervous system of the dog

1954 • 695 citations

The glyoxylic acid fluorescence histochemical method: a detailed account of the methodology for the visualization of central catecholamine neurons

1974 • 563 citations

Serotonin Content of Some Mammalian Tissues and Urine and a Method for Its Determination

1953 • 504 citations

Serotonin nerve terminals in adult rat neocortex

1975 • 504 citations

The postnatal ontogeny of monoamine-containing neurones in the central nervous system of the albino rat

1972 • 396 citations

Serotonin content of the brain stem nuclei in the rat

1974 • 380 citations

THE DISTRIBUTION OF SEROTONIN, 5‐HYDROXYTRYPTOPHAN DECARBOXYLASE, AND MONOAMINE OXIDASE IN BRAIN*

1957 • 350 citations

Serotonin distribution in the nuclei of the rat hypothalamus and preoptic region

1974 • 246 citations

IMMUNOFLUORESCENCE OF DOPAMINE-β-HYDROXYLASE APPLICATION OF IMPROVED METHODOLOGY TO THE LOCALIZATION OF THE PERIPHERAL AND CENTRAL NORADRENERGIC NERVOUS SYSTEM

1973 • 245 citations

Monoamine-synthesizing enzymes in central dopaminergic, noradrenergic and serotonergic neurons. Immunocytochemical localization by light and electron microscopy.

1976 • 236 citations

MICROANALYTICAL PROCEDURES FOR FLUORO‐METRIC ASSAY OF BRAIN DOPA‐5HTP DECARBOXYLASE, NOREPINEPHRINE AND SEROTONIN, AND A DETAILED MAPPING OF DECARBOXYLASE ACTIVITY IN BRAIN

1961 • 235 citations

Further mapping of central 5-hydroxytryptamine neurons: studies with the neurotoxic dihydroxytryptamines.

1974 • 223 citations

Indoleamine neurons and their processes in the normal rat brain and in chronic diet‐induced thiamine deficiency demonstrated by uptake of ³H‐Serotonin

1977 • 220 citations

Serotonin-containing neuronal perikarya and terminals: differential effects of p-chlorophenylalanine

1973 • 199 citations

Quantitation of Fluorescence of Biogenic Monoamines

1971 • 187 citations

Localization of tritiated serotonin in rat brain by electron-microscopic autoradiography.

1967 • 179 citations

The topographical distribution of serotoninergic terminals in the spinal cord of the cat: biochemical mapping by the combined use of microdissection and microassay procedures

1977 • 178 citations

Modification of the Falck-Hillarp formaldehyde fluorescence method using the vibratome®: simple, rapid and sensitive localization of catecholamines in sections of unfixed or formalin fixed brain tissue

1972 • 158 citations

Classification of monoamine neurones in the rat mesencephalon: Distribution of a new monoamine neurone system

1971 • 154 citations

Fluorescent Protein Tracing

1976 • 149 citations

Immunohistochemical localization of aromatic L-amino acid decarboxylase (DOPA decarboxylase) in central dopamine and 5-hydroxytryptamine nerve cell bodies of the rat

1973 • 139 citations

An improved histofluorescence procedure for freeze-dried paraffin-embedded tissue based on combined formaldehyde-glyoxylic acid perfusion with high magnesium content and acid pH

1976 • 137 citations

A modification of the histochemical fluorescence method for the improved localization of 5-hydroxytryptamine

1967 • 136 citations

Localization of Indolealkylamines in CNS

1968 • 123 citations

Histochemical fluorescence of tissue and brain mono amines: Results in 18 minutes using the sucrose-phosphate-glyoxylic acid (SPG) method

1976 • 120 citations

APPLICATIONS OF IMMUNOHISTOCHEMISTRY TO STUDIES ON MONOAMINE CELL SYSTEMS WITH SPECIAL REFERENCE TO NERVOUS TISSUES*

1975 • 119 citations

Serotonin distribution in the limbic system of the rat

1974 • 116 citations

Specificity in immunocytochemical staining.

1976 • 115 citations

The Specificity of Serological Reactions

1946 • 113 citations

Antibodies to Indolealkylamines; Serotonin and Melatonin

1974 • 113 citations

Brain tryptophan hydroxylase: purification of, production of antibodies to, and cellular and ultrastructural localization in serotonergic neurons of rat midbrain.

1975 • 109 citations

Distribution of serotonin and synthesizing enzymes in discrete areas of the brain.

1977 • 104 citations

A rapid, simple and sensitive method for the demonstration of central catecholamine-containing neurons and axons by glyoxylic acid-induced fluorescence. II. A detailed description of methodology.

1976 • 102 citations

5-HYDROXYTRYPTAMINE (SEROTONIN, ENTERAMINE) CONTENT OF STRUCTURES OF THE LIMBIC SYSTEM

1957 • 96 citations

Identification and quantitation of a new indolealkylamine in rat hypothalamus

1973 • 83 citations

Characterization of antral gastrin cells with region-specific antisera.

1977 • 81 citations

Methods in brain research

1976 • 72 citations

Simultaneous determination of indole- and catecholamines in small brain regions in the rat using a weak cation exchange resin

1976 • 71 citations

ANTIBODIES TO SEROTONIN

1967 • 70 citations

A RAPID, SIMPLE AND SENSITIVE METHOD FOR THE DEMONSTRATION OF CENTRAL CATECHOLAMINE-CONTAINING NEURONS AND AXONS BY GLYOXYLIC ACID-INDUCED FLUORESCENCE

1976 • 63 citations

Serotonin: Radioimmunoassay

1973 • 55 citations

Antibodies to morphine, barbiturates, and serotonin.

1973 • 55 citations

Magnesium ions in catecholamine fluorescence histochemistry

1977 • 37 citations

A rapid, simple and more sensitive method for the demonstration of central catecholamine-containing neurons and axons by glyoxylic acid induced fluorescence: I. Specificity.

1975 • 37 citations

Intraneuronal indolamines in the central nervous system.

1976 • 15 citations

On the visualization of central dopamine and noradrenaline nerve terminals in cryostat sections.

1976 • 14 citations

A modification of the Falck-Hillarp technique for 5-HT fluorescence employing hypertonic formaldehyde perfusion.

1976 • 12 citations

The biochemical and biobehavioral profile of 5-methoxytryptamine.

1976 • 10 citations

Application of immunology to neurochemistry.

1969 • 4 citations

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