Epidermal growth factor receptor gene-amplified MDA-468 breast cancer cell line and its nonamplified variants.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Epidermal Growth Factor

1979 • 2,964 citations

Epidermal growth factor.

1990 • 1,645 citations

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

1985 • 1,523 citations

Cellular resistance to actinomycin D in Chinese hamster cells in vitro: cross-resistance, radioautographic, and cytogenetic studies.

1970 • 752 citations

Expression Cloning of Human EGF Receptor Complementary DNA: Gene Amplification and Three Related Messenger RNA Products in A431 Cells

1984 • 406 citations

Amplification and Enhanced Expression of the Epidermal Growth Factor Receptor Gene in A431 Human Carcinoma Cells

1984 • 400 citations

Increased phosphotyrosine content and inhibition of proliferation in EGF-treated A431 cells

1981 • 392 citations

MDA-468, a human breast cancer cell line with a high number of epidermal growth factor (EGF) receptors, has an amplified EGF receptor gene and is growth inhibited by EGF

1985 • 332 citations

Cloning of Human Tumor Stem Cells

1981 • 269 citations

Relation of epidermal growth factor receptor concentration to growth of human epidermoid carcinoma A431 cells.

1984 • 245 citations

Characterization of epidermal growth factor receptor gene expression in malignant and normal human cell lines.

1984 • 231 citations

Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization

1982 • 192 citations

Precise localization of human beta-globin gene complex on chromosome 11.

1979 • 175 citations

Structure and localization of genes encoding aberrant and normal epidermal growth factor receptor RNAs from A431 human carcinoma cells.

1985 • 171 citations

Biosynthesis of the epidermal growth factor receptor in A431 cells.

1984 • 156 citations

Epidermal growth factor stimulates the synthesis of its own receptor in a human breast cancer cell line.

1986 • 145 citations

Hyperproduction and gene amplification of the epidermal growth factor receptor in squamous cell carcinomas.

1985 • 139 citations

Evidence for increased epidermal growth factor receptors in human sarcomas

1985 • 113 citations

Amplified, overexpressed and rearranged epidermal growth factor receptor gene in a human astrocytoma cell line

1985 • 75 citations

Biological action of epidermal growth factor and its functional receptors in normal mammary epithelial cells.

1983 • 74 citations

A Human Breast Adenocarcinoma With Chromosome and Isoenzyme Markers Similar to Those of the Hela Line<xref ref-type="fn" rid="fn2">2</xref>

1979 • 62 citations

Ribosomal and human-homologous repeated DNA distribution in the orangutan <i>(Pongo pygmaeus)</i>

1978 • 41 citations

Anchorage-independent growth of normal human mesothelial cells: A sensitive bioassay for EGF which discloses the absence of this factor in fetal calf serum

1985 • 25 citations

Protocols of procedures and techniques in chromosome analysis of tumor stem cell cultures in soft agar.

1980 • 14 citations