Absence of human papillomavirus type 16 E6 transcripts in HPV 16‐infected, cytologically normal cervical scrapings

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

The Human Papilloma Virus-16 E7 Oncoprotein Is Able to Bind to the Retinoblastoma Gene Product

1989 • 3,036 citations

Association of Human Papillomavirus Types 16 and 18 E6 Proteins with p53

1990 • 2,587 citations

A papillomavirus DNA from a cervical carcinoma and its prevalence in cancer biopsy samples from different geographic regions.

1983 • 2,011 citations

Amplification of a gene encoding a p53-associated protein in human sarcomas

1992 • 1,959 citations

Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product.

1989 • 1,186 citations

Recent Advances in the Polymerase Chain Reaction

1991 • 1,068 citations

Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines

1987 • 760 citations

Heterogeneity of the human papillomavirus group

1989 • 677 citations

Transcription of human papillomavirus type 16 early genes in a cervical cancer and a cancer-derived cell line and identification of the E7 protein.

1986 • 665 citations

Papillomaviruses in anogenital cancer as a model to understand the role of viruses in human cancers.

1989 • 522 citations

Different human cervical carcinoma cell lines show similar transcription patterns of human papillomavirus type 18 early genes.

1986 • 440 citations

Human papillomavirus type 16 and 18 gene expression in cervical neoplasias

1992 • 415 citations

Clonal p53 mutation in primary cervical cancer: association with human-papillomavirus-negative tumours

1992 • 313 citations

Charles S. Mott prize papillomaviruses in human cancer

1987 • 283 citations

Papillomavirus polypeptides E6 and E7 are zinc-binding proteins

1989 • 239 citations

Integration of human papillomavirus type 16 into cellular DNA of cervical carcinoma: Preferential deletion of the E2 gene and invariable retention of the long control region and the E6/E7 open reading frames

1987 • 214 citations

General primer‐mediated polymerase chain reaction permits the detection of sequenced and still unsequenced human papillomavirus genotypes in cervical scrapes and carcinomas

1990 • 180 citations

Human papillomavirus type 16 DNA in cervical smears as predictor of high-grade cervical cancer

1992 • 167 citations

Complete sequence of a gene encoding a human type I keratin: sequences homologous to enhancer elements in the regulatory region of the gene.

1985 • 142 citations

Increased detection rate of human papillomavirus in cervical scrapes by the polymerase chain reaction as compared to modified FISH and southern‐blot analysi

1989 • 126 citations

The polymerase chain reaction: Miracle or mirage? A critical review of its uses and limitations in diagnosis and research

1990 • 121 citations

Human papillomavirus detection in urine samples from male patients by the polymerase chain reaction

1989 • 94 citations

Uniformity of the Splicing Pattern of the E6/E7 Transcripts in Human Papillomavirus Type 16-transformed Human Fibroblasts, Human Cervical Premalignant Lesions and Carcinomas

1990 • 70 citations

Intracellular localization and DNA-binding properties of human papillomavirus type 18 E6 protein expressed with a baculovirus vector

1989 • 63 citations

Analysis of human papillomavirus type 16 E6-E7 transcription in cervical carcinomas and normal cervical epithelium using the polymerase chain reaction

1990 • 51 citations

Detection of the human papilloma virus type 16 mRNA‐transcripts in cytological abnormal scrapings

1992 • 22 citations

Conservation of HPV‐16 E6/E7 ORF sequences in a cervical carcinoma

1992 • 21 citations

Detection of human papillomavirus type 16 E6/E7 transcripts in fixed paraffin-embedded cervical cancers by the polymerase chain reaction

1991 • 8 citations