A molecular basis for nitric oxide sensing by soluble guanylate cyclase

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

1981 • 1,624 citations

Blood Flow Regulation by S -Nitrosohemoglobin in the Physiological Oxygen Gradient

1997 • 1,050 citations

Guanylate cyclase and the ⋅NO/cGMP signaling pathway

1999 • 998 citations

Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide

1990 • 996 citations

Nitric oxide synthase: Aspects concerning structure and catalysis

1994 • 865 citations

Control of coronary vascular tone by nitric oxide.

1990 • 713 citations

“NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms

1996 • 660 citations

Soluble Guanylate Cyclase from Bovine Lung: Activation with Nitric Oxide and Carbon Monoxide and Spectral Characterization of the Ferrous and Ferric States

1994 • 641 citations

Oxidation of nitrogen oxides by bound dioxygen in hemoproteins

1981 • 633 citations

Mechanism of Nitric Oxide Release from S-Nitrosothiols

1996 • 580 citations

Reactions between nitric oxide and haemoglobin under physiological conditions

1998 • 577 citations

Signal transduction mechanisms involving nitric oxide

1991 • 538 citations

Soluble guanylate cyclase purified from bovine lung contains heme and copper

1981 • 328 citations

Requirement of thiols for activation of coronary arterial guanylate cyclase by glyceryl trinitrate and sodium nitrite possible involvement of S-nitrosothiols

1980 • 313 citations

Spectral and Kinetic Studies on the Activation of Soluble Guanylate Cyclase by Nitric Oxide

1996 • 308 citations

Spectroscopic studies and bonding model for nitric oxide complexes of iron porphyrins

1974 • 292 citations

Cooperativity in the dissociation of nitric oxide from hemoglobin.

1976 • 289 citations

Activation of soluble guanylate cyclase by NO-hemoproteins involves NO-heme exchange. Comparison of heme-containing and heme-deficient enzyme forms.

1986 • 272 citations

Reaction of nitric oxide with heme proteins and model compounds of hemoglobin

1987 • 252 citations

Activation of purified soluble guanylate cyclase by protoporphyrin IX.

1982 • 206 citations

Inhibition of human platelet aggregation by S-nitrosothiols. Heme-dependent activation of soluble guanylate cyclase and stimulation of cyclic GMP accumulation.

1983 • 184 citations

Kinetics of Nitric Oxide Dissociation from Five- and Six-Coordinate Nitrosyl Hemes and Heme Proteins, Including Soluble Guanylate Cyclase

1997 • 169 citations

Identification of Histidine 105 in the β1 Subunit of Soluble Guanylate Cyclase as the Heme Proximal Ligand

1998 • 154 citations

Electron Paramagnetic Resonance Spectral Evidence for the Formation of a Pentacoordinate Nitrosyl-Heme Complex on Soluble Guanylate Cyclase

1995 • 153 citations

S-Transnitrosation reactions are involved in the metabolic fate and biological actions of nitric oxide.

1998 • 129 citations

Synthesis and Structural Characterization of Several Ruthenium Porphyrin Nitrosyl Complexes

1997 • 118 citations

The chemical mechanism of microbioal denitrification

1982 • 118 citations

Purification and properties of protocatechuate 3,4-dioxygenase from Pseudomonas putida. A new iron to subunit stoichiometry.

1981 • 113 citations

Localization of the Heme Binding Region in Soluble Guanylate Cyclase^†

1997 • 111 citations

Regulation of purified soluble guanylate cyclase by porphyrins and metalloporphyrins: a unifying concept.

1984 • 102 citations

Nitrosyliron(III) hemoglobin: autoreduction and spectroscopy

1986 • 98 citations

Regeneration of the Ferrous Heme of Soluble Guanylate Cyclase from the Nitric Oxide Complex: Acceleration by Thiols and Oxyhemoglobin

1998 • 93 citations

Electrochemical and spectral characterization of iron mono- and dinitrosyl porphyrins

1983 • 93 citations

Evidence for N‐acetylcysteine‐sensitive nitric oxide storage as dinitrosyl‐iron complexes in lipopolysaccharide‐treated rat aorta

1996 • 85 citations

Dinitrosyl-Dithiol-Iron Complexes, Nitric Oxide (NO) Carriers In Vivo, as Potent Inhibitors of Human Glutathione Reductase and Glutathione-S-Transferase

1997 • 76 citations

EPR Characterization of Axial Bond in Metal Center of Native and Cobalt-substituted Guanylate Cyclase

1999 • 69 citations

The role of diffusion in limiting the rate of ligand binding to hemoglobin.

1980 • 52 citations

Resonance Raman Characterization of the Heme Domain of Soluble Guanylate Cyclase

1998 • 34 citations

Spectroscopic properties of the nitric oxide derivative of ferrous man, horse, and ruminant hemoglobins: A comparative study

1992 • 11 citations

[39] Molecular cloning of membrane forms of guanylyl cyclase

1991 • 3 citations