Mutational Analysis of the Tyrosine Phosphatome in Colorectal Cancers

Mutations of the BRAF gene in human cancer

2002 • 10,249 citations

PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

1997 • 4,753 citations

Oncogenic kinase signalling

2001 • 3,632 citations

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1997 • 2,746 citations

RAF/RAS oncogenes and mismatch-repair status

2002 • 1,205 citations

Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia

2003 • 1,019 citations

Oncogenic forms of p53 inhibit p53-regulated gene expression

1992 • 933 citations

Protein tyrosine phosphatases in signal transduction

1997 • 766 citations

Structural and Evolutionary Relationships among Protein Tyrosine Phosphatase Domains

2001 • 694 citations

A Phosphatase Associated with Metastasis of Colorectal Cancer

2001 • 641 citations

Mutational Analysis of the Tyrosine Kinome in Colorectal Cancers

2003 • 487 citations

THE CROONIAN LECTURE 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and disease

1998 • 401 citations

Alterations of the PPP2R1B Gene in Human Lung and Colon Cancer

1998 • 358 citations

Oncogenic Forms of p53 Inhibit p53-Regulated Gene Expression

1992 • 333 citations

Phosphorylation and Free Pool of β-Catenin Are Regulated by Tyrosine Kinases and Tyrosine Phosphatases during Epithelial Cell Migration

1999 • 286 citations

Receptor protein-tyrosine phosphatase gamma is a candidate tumor suppressor gene at human chromosome region 3p21.

1991 • 207 citations

Prevalence of somatic alterations in the colorectal cancer cell genome

2002 • 179 citations

A Matter of Dosage

2002 • 130 citations

Identification of the Cell Cycle Regulator VCP (p97/CDC48) as a Substrate of the Band 4.1-related Protein-tyrosine Phosphatase PTPH1

1999 • 106 citations

The Protein Tyrosine Phosphatase Pez Is a Major Phosphatase of Adherens Junctions and Dephosphorylates β-Catenin

2003 • 98 citations

Protein tyrosine phosphatase RQ is a phosphatidylinositol phosphatase that can regulate cell survival and proliferation

2003 • 84 citations

The FHIT and PTPRG genes are deleted in benign proliferative breast disease associated with familial breast cancer and cytogenetic rearrangements of chromosome band 3p14.

1996 • 65 citations

Loss of heterozygosity at the familial RCC t(3;8) locus in most clear cell renal carcinomas.

1995 • 64 citations

Protein-tyrosine Phosphatase PTPL1/FAP-1 Triggers Apoptosis in Human Breast Cancer Cells

2002 • 62 citations

Extinction of Insulin-Like Growth Factor-I Mitogenic Signaling by Antiestrogen-Stimulated Fas-Associated Protein Tyrosine Phosphatase-1 in Human Breast Cancer Cells

1998 • 47 citations

Phosphoregulators: Protein Kinases and Protein Phosphatases of Mouse

2003 • 47 citations

Cyclic changes in the organization of cell adhesions and the associated cytoskeleton, induced by stimulation of tyrosine phosphorylation in bovine aortic endothelial cells

1997 • 38 citations

Structure of the Human Receptor Tyrosine Phosphatase Gamma Gene (PTPRG) and Relation to the Familial RCC t(3;8) Chromosome Translocation

1996 • 38 citations

Novel receptor protein tyrosine phosphatase (RPTP?) and acidic fibroblast growth factor (FGF-1) transcripts delineate a rostrocaudal boundary in the granule cell layer of the murine cerebellar cortex

1998 • 37 citations