Strategies for automated fetal cell screening

A comparison of different focus functions for use in autofocus algorithms

1985 • 425 citations

Severe limb abnormalities after chorion villus sampling at 56-66 days' gestation

1991 • 378 citations

PCR Quantitation of Fetal Cells in Maternal Blood in Normal and Aneuploid Pregnancies

1997 • 366 citations

Fetal gender and aneuploidy detection using fetal cells in maternal blood: analysis of NIFTY I data

2002 • 340 citations

Fetal nucleated cells in maternal peripheral blood: frequency and relationship to gestational age

1993 • 225 citations

Detection of Fetal Trisomies 21 and 18 From Maternal Blood Using Triple Gradient and Magnetic Cell Sorting

1993 • 198 citations

Slide-Based Laser Scanning Cytometry

1997 • 188 citations

Magnetic cell sorting and the transferrin receptor as potential means of prenatal diagnosis from maternal blood

1992 • 139 citations

Contrast enhancement of medical images using multiscale edge representation

1994 • 133 citations

Prenatal diagnosis from maternal blood: simultaneous immunophenotyping and FISH of fetal nucleated erythrocytes isolated by negative magnetic cell sorting.

1993 • 129 citations

Apoptosis in fetal nucleated erythrocytes circulating in maternal blood

2000 • 123 citations

MATERNAL SYNTHESIS OF HÆMOGLOBIN F IN PREGNANCY

1973 • 122 citations

FISH and chips: Automation of fluorescent dot counting in interphase cell nuclei

1997 • 121 citations

Erythroid‐specific antibodies enhance detection of fetal nucleated erythrocytes in maternal blood

1993 • 120 citations

High‐resolution cytometry of FISH dots in interphase cell nuclei

1999 • 117 citations

Development of non‐invasive fetal DNA diagnosis from maternal blood

1995 • 112 citations

Detection and isolation of fetal cells from maternal blood using the flourescence‐activated cell sorter (FACS)

1981 • 108 citations

High-resolution cytometry of FISH dots in interphase cell nuclei

1999 • 105 citations

Maternal origin of nucleated erythrocytes in peripheral venous blood of pregnant women

1995 • 85 citations

Flow sorting of fetal erythroblasts using intracytoplasmic anti‐fetal haemoglobin: Preliminary observations on maternal samples

1995 • 72 citations

Prenatal Diagnosis Using Fetal Cells Isolated From Maternal Peripheral Blood: A Review

1996 • 67 citations

Cancer Detection by Quantitative Fluorescence Image Analysis

1988 • 63 citations

Frequency of Fetal Cells in Sorted Subpopulations of Nucleated Erythroid and CD34+ Hematopoietic Progenitor Cells From Maternal Peripheral Blood

1997 • 62 citations

Fetal RhD genotyping in fetal cells flow sorted from maternal blood

1996 • 58 citations

Automated FISH spot counting in interphase nuclei: Statistical validation and data correction

1998 • 57 citations

High-performance autofocus circuit for biological microscopy

1998 • 56 citations

Ultra-rare-event detection performance of a custom scanning cytometer on a model preparation of fetal nRBCs

2000 • 54 citations

Strategies for Rare-Event Detection: An Approach for Automated Fetal Cell Detection in Maternal Blood

1998 • 49 citations

Search for the optimal fetal cell antibody: results of immunophenotyping studies using flow cytometry

1997 • 47 citations

Improved fetal nucleated erythrocyte sorting purity using intracellular antifetal hemoglobin and Hoechst 33342

1996 • 44 citations

Methods for automatic multiparameter analysis of fluorescence in situ hybridized specimens with a laser scanning cytometer

1997 • 43 citations

Contrast enhancement of medical images using multiscale edge representation

1994 • 42 citations

<title>Reconstructing 3-D Specimens From 2-D Section Images</title>

1971 • 40 citations

Development of a preparation and staining method for fetal erythroblasts in maternal blood: Simultaneous immunocytochemical staining and FISH analysis

1998 • 35 citations

Prenatal diagnosis of trisomy 13 on fetal cells obtained from maternal blood after minor enrichment.

1998 • 33 citations

Contrast enhancement via multiscale gradient transformation

2002 • 33 citations

Apoptosis in Maternal Peripheral Blood during Pregnancy

2000 • 31 citations

FISH image analysis

1996 • 29 citations

Image analysis combined with quantitative cytochemistry

1986 • 27 citations

Counting, measuring, and mapping in fish‐labelled cells: Sample size considerations and implications for automation

1994 • 25 citations

Dot count proportion estimation in FISH specimens

1995 • 25 citations

Detection of ‘rare event’ fetal erythroblasts in maternal blood using automated microscopy

1996 • 24 citations

Inability to Clonally Expand Fetal Progenitors from Maternal Blood

2002 • 23 citations

Automation of spot counting in interphase cytogenetics using brightfield microscopy

1996 • 22 citations

Detection of fetal erythroblasts in maternal blood by onestep gradient enrichment and immunocytochemical recognition

1996 • 19 citations

Three‐dimensional distribution of damaged cells in cryopreserved pancreatic islets as determined by laser scanning confocal microscopy

1993 • 18 citations

Digital image color compensation with unequal integration periods

1994 • 18 citations

<title>Automated microscopy system for detection and genetic characterization of fetal nucleated red blood cells on slides</title>

1998 • 17 citations

Evaluation of a Culture System for Enrichment of CD34+ Hematopoietic Progenitor Cells Present in Maternal Blood

2002 • 15 citations

Fetal cell identifiers: Results of microscope slide–based immunocytochemical studies as a function of gestational age and abnormality

1999 • 15 citations

Digital image color compensation with unequal integration periods

1994 • 13 citations

Improved fetal nucleated erythrocyte sorting purity using intracellular antifetal hemoglobin and Hoechst 33342

1996 • 6 citations

Ultra-rare-event detection performance of a custom scanning cytometer on a model preparation of fetal nRBCs

2000 • 2 citations

Prenatal diagnosis of trisomy 13 on fetal cells obtained from maternal blood after minor enrichment

1998 • 2 citations