Automated FISH spot counting in interphase nuclei: Statistical validation and data correction

A Threshold Selection Method from Gray-Level Histograms

1979 • 39,466 citations

Image analysis and mathematical morphology

1982 • 8,253 citations

Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.

1986 • 3,231 citations

Morphological grayscale reconstruction in image analysis: applications and efficient algorithms

1993 • 1,886 citations

Distribution-Free Statistical Tests

1970 • 1,755 citations

In situ hybridization as a tool to study numerical chromosome aberrations in solid bladder tumors

1988 • 462 citations

Applying watershed algorithms to the segmentation of clustered nuclei

1998 • 432 citations

Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84

1986 • 380 citations

Detection of trisomy 12 in chronic lymphocytic leukemia by fluorescence in situ hybridization to interphase cells: a simple and sensitive method

1992 • 159 citations

Interphase cytogenetics of hematological cancer: comparison of classical karyotyping and in situ hybridization using a panel of eleven chromosome specific DNA probes.

1991 • 138 citations

Automatic focusing by correlative methods

1987 • 123 citations

FISH and chips: Automation of fluorescent dot counting in interphase cell nuclei

1997 • 121 citations

Interphase cytogenetics of tumours

1992 • 82 citations

Interphase cytogenetic analysis detects minimal residual disease in a case of acute lymphoblastic leukemia and resolves the question of origin of relapse after allogeneic bone marrow transplantation

1991 • 63 citations

Statistical methods in interphase cytogenetics: An experimental approach

1993 • 52 citations

Autofocusing in microscopy based on the OTF and sampling

1994 • 49 citations

Statistical analysis of in situ hybridization data: Derivation and use of the Zmax test

1992 • 38 citations

Color compensation for digitized FISH images

1993 • 33 citations

Counting, measuring, and mapping in fish‐labelled cells: Sample size considerations and implications for automation

1994 • 25 citations

Dot count proportion estimation in FISH specimens

1995 • 25 citations

Automation of spot counting in interphase cytogenetics using brightfield microscopy

1996 • 22 citations

Interlaboratory variability in fluorescence in situ hybridization analysis

1996 • 14 citations

Comparison of automated and manual analysis of interphase in situ hybridization signals in tissue sections and nuclear suspensions

1996 • 5 citations