Determinants of polycyclic aromatic hydrocarbon-DNA adducts in human placenta.

Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes Memorial Lecture.

1982 • 1,559 citations

Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes.

1980 • 1,277 citations

32P-labeling test for DNA damage.

1981 • 531 citations

The Ah Locus: Genetic Differences in Toxicity, Cancer, Mutation, and Birth Defects

1989 • 458 citations

Expression of CYP1A1 Gene in Patients With Lung Cancer: Evidence for Cigarette Smoke-Induced Gene Expression in Normal Lung Tissue and for Altered Gene Regulation in Primary Pulmonary Carcinomas

1990 • 330 citations

Positive correlation between high aryl hydrocarbon hydroxylase activity and primary lung cancer as analyzed in cryopreserved lymphocytes.

1982 • 269 citations

Detection of Smoking-Related Covalent DNA Adducts in Human Placenta

1986 • 261 citations

Detection of benzo[a]pyrene diol epoxide-DNA adducts in peripheral blood lymphocytes and antibodies to the adducts in serum from coke oven workers.

1985 • 190 citations

A pilot project in molecular cancer epidemiology: determination of benzo[a]pyrene — DNA adducts in animal and human tissues by immunoassays

1982 • 167 citations

Quantitation of benzo(a)pyrene-deoxyguanosine adducts by radioimmunoassay.

1980 • 149 citations

Monoclonal antibodies to DNA modified by a benzo[a]pyrene diol epoxide

1984 • 128 citations

Genetic control of interindividual variations in the inducibility of aryl hydrocarbon hydroxylase in cultured human lymphocytes.

1976 • 126 citations

An applied synchronous fluorescence spectrophotometric assay to study benzo[a]pyrene-diolepoxide-DNA adducts

1985 • 117 citations

Fluorescence and mass spectral evidence for the formation of benzo[a]pyrene anti-diol-epoxide—DNA and —hemoglobin adducts in humans

1989 • 110 citations

Detection of benzo[a]pyrene diol epoxide-DNA adducts in human placenta.

1988 • 104 citations

Interlaboratory comparison of antisera and immunoassays for benzo[a] pyrene-diol-epoxide-I-modified DNA

1988 • 86 citations

Comparison of pulmonary DNA adduct levels, measured by ³²P-postlabelling and aryl hydrocarbon hydroxylase activity in lung parenchyma of smokers and ex-smokers

1991 • 81 citations

Alkyl and aryl carcinogen adducts detected in human peripheral lung

1989 • 76 citations

The metabolic activation of 7-methylbenz(a)anthracene in mouse skin

1977 • 75 citations

Derivative fluorescence spectral analysis of polycyclic aromatic hydrocarbon-DNA adducts in human placenta

1989 • 74 citations

Polycyclic aromatic hydrocarbon-DNA adducts in spontaneously aborted fetal tissue

1990 • 59 citations

Effects of Smoking on Benzo(a)pyrene Metabolism by Human Placental Microsomes

1979 • 57 citations

Benzo[a]pyrene Metabolism: Activation and Detoxification

1978 • 51 citations

Monoclonal antibody phenotyping of interindividual differences in cytochrome P-450-dependent reactions of single and twin human placenta.

1984 • 49 citations

Evaluation of the fiber-optic antibody-based fluoroimmunosensor for DNA adducts in human placenta samples

1991 • 46 citations

The binding efficiency of polyclonal and monoclonal antibodies to DNA modified with benzo[a]pyrene diol epoxide is dependent on the level of modification. Implications for quantitation of benzo[a]pyrene-DNA adducts in vivo

1987 • 45 citations

Synchronous fluorescence spectroscopic, immunoaffinity chromatographic and ³²P-postlabeling analysis of human placental DNA known to contain benzo[a]pyrene diol apoxide adducts

1990 • 44 citations

Modification of deoxyribonucleic acid by a diol epoxide of benzo[a]pyrene. Relation to deoxyribonucleic acid structure and conformation and effects on transfectional activity

1979 • 42 citations

Detection of Carcinogen-DNA Adducts in Human Cells and Antibodies to these Adducts in Human Sera

2015 • 33 citations

Maternal Smoking Increases Xenobiotic Metabolism in Placenta but Not Umbilical Vein Endothelium

1984 • 31 citations

Aryl hydrocarbon hydroxylase in cultured lymphocytes of twins.

1978 • 29 citations

P-450 Cytochromes in the Human Placenta: Oxidations of Xenobiotics and Endogenous Steroids

1987 • 22 citations

Range of environmentally responsive monooxygenase activities in human placental microsomes determined by direct fluorescence techniques

1981 • 20 citations

Low-speed purification of human placental nuclei

1984 • 19 citations