Monoclonal antibody phenotyping of interindividual differences in cytochrome P-450-dependent reactions of single and twin human placenta.

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection

1973 • 2,275 citations

Substrate-inducible Microsomal Aryl Hydroxylase in Mammalian Cell Culture

1968 • 1,691 citations

Benzo[alpha]pyrene metabolism, activation and carcinogenesis: role and regulation of mixed-function oxidases and related enzymes.

1980 • 1,277 citations

POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN

1977 • 1,196 citations

The Human Placenta

1970 • 934 citations

Defective N-oxidation of sparteine in man: A new pharmacogenetic defect

1979 • 647 citations

Multiplicity of mammalian microsomal cytochromes P-45.

1979 • 633 citations

An improved assay of 7-ethoxycoumarin O-deethylase activity: induction of hepatic enzyme activity in C57BL/6J and DBA/2J mice by phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin.

1978 • 618 citations

Aryl Hydrocarbon Hydroxylase Inducibility and Bronchogenic Carcinoma

1973 • 601 citations

Aryl hydrocarbon (benzo[a]pyrene) hydroxylase in microsomes from rat tissues: Differential inhibition and stimulation by benzoflavones and organic solvents

1971 • 374 citations

A microsome-dependent binding of benzo[a]pyrene to DNA.

1969 • 332 citations

Metabolic Interactions Among Environmental Chemicals and Drugs

1972 • 261 citations

Cigarette Smoking: Stimulatory Effect on Metabolism of 3,4-Benzpyrene by Enzymes in Human Placenta

1968 • 194 citations

Microsomes, drug oxidations, and drug toxicity

1982 • 187 citations

Monoclonal antibodies that inhibit enzyme activity of 3-methylcholanthrene-induced cytochrome P-450.

1982 • 170 citations

Aryl hydrocarbon hydroxylase activity in human placenta from cigarette smoking and nonsmoking women.

1969 • 170 citations

Questionable Relation of Aryl Hydrocarbon Hydroxylase to Lung-Cancer Risk

1977 • 138 citations

Comparative metabolism of benzo[a]pyrene and drugs in human liver

1977 • 104 citations

Comparison of the O‐dealkylation of 7‐ethoxycoumarin and the hydroxylation of benzo [a] pyrene in human placenta

1974 • 102 citations

Phenotyping of cytochromes P -450 in human tissues with monoclonal antibodies

1982 • 94 citations

Evidence for an enzymatic defect in the 4‐hydroxylation of debrisoquine by human liver.

1981 • 93 citations

Genetic expression of aryl hydrocarbon hydroxylase induction

1973 • 59 citations

Effects of Smoking on Benzo(a)pyrene Metabolism by Human Placental Microsomes

1979 • 57 citations

Population distribution of placental benzo(α)pyrene metabolism in smokers

1983 • 42 citations

Further studies on the properties of human placental microsomal cytochrome P-450

1976 • 36 citations

Aryl hydrocarbon hydroxylase in cultured lymphocytes of twins.

1978 • 29 citations

The specificity and multiplicity of human placental xenobiotic-metabolizing monooxygenase system studied by potential substrates, inhibitors and gel electrophoresis.

1979 • 23 citations

Metabolites of benzo(a) pyrene produced by placental microsomes from cigarette smokers and nonsmokers

1977 • 23 citations