The chromo shadow domain, a second chromo domain in heterochromatin-binding protein 1, HP1

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

Amino acid substitution matrices from protein blocks.

1992 • 5,998 citations

Profile analysis: detection of distantly related proteins.

1987 • 1,308 citations

The PHD finger: Implications for chromatin-mediated transcriptional regulation

1995 • 857 citations

The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila.

1991 • 566 citations

PHD-an automatic mail server for protein secondary structure prediction

1994 • 561 citations

The protein encoded by the Drosophila position-effect variegation suppressor gene Su(var)3-9 combines domains of antagonistic regulators of homeotic gene complexes.

1994 • 560 citations

Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster.

1990 • 554 citations

A method to predict functional residues in proteins

1995 • 418 citations

Distribution patterns of HP1, a heterochromatin-associated nonhistone chromosomal protein of Drosophila.

1989 • 400 citations

Imprinting a determined state into the chromatin of Drosophila

1990 • 391 citations

Dosage-dependent modifiers of position effect variegation in Drosophila and a mass action model that explains their effect.

1988 • 320 citations

PH domain: the first anniversary

1994 • 318 citations

Improved sensitivity of profile searches through the use of sequence weights and gap excision

1994 • 301 citations

A sequence motif found in aDrosophilaheterochromatin protein is conserved in animals and plants

1991 • 273 citations

The Drosophila Polycomb-group gene Enhancer of zeste contains a region with sequence similarity to trithorax.

1993 • 235 citations

Analysis of the functional role of the Polycomb chromo domain in Drosophila melanogaster.

1992 • 231 citations

A mammalian DNA-binding protein that contains a chromodomain and an SNF2/SWI2-like helicase domain.

1993 • 230 citations

Genetic analysis of the enhancer of zeste locus and its role in gene regulation in Drosophila melanogaster.

1990 • 209 citations

Switching gene swi6, involved in repression of silent mating-type loci in fission yeast, encodes a homologue of chromatin-associated proteins from Drosophila and mammals

1994 • 163 citations

Chromatin multiprotein complexes involved in the maintenance of transcription patterns

1995 • 152 citations

Mechanisms of heritable gene repression during development of Drosophila

1993 • 113 citations

Overlapping domains of the heterochromatin-associated protein HP1 mediate nuclear localization and heterochromatin binding.

1993 • 95 citations

Cloning and expression of Drosophila HP1 homologs from a mealybug, Pianococcus citri

1992 • 62 citations

swi6, a gene required for mating-type switching, prohibits meiotic recombination in the mat2-mat3 "cold spot" of fission yeast.

1991 • 62 citations

The Drosophila Polycomb-Group Gene Enhancer of zeste Contains a Region with Sequence Similarity to trithorax

1993 • 53 citations

Heterochromatin protein 1, a known suppressor of position-effect variegation, is highly conserved inDrosophila

1992 • 36 citations

Trans-regulation of homeotic genes in Drosophila.

1992 • 27 citations