Casein Kinase II Phosphorylation Site Mutations in c-Myb Affect DNA Binding and Transcriptional Cooperativity with NF-M

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Phosphorylated CREB binds specifically to the nuclear protein CBP

1993 • 2,039 citations

Nuclear protein CBP is a coactivator for the transcription factor CREB

1994 • 1,447 citations

A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

1991 • 1,074 citations

Luciferase reporter gene vectors for analysis of promoters and enhancers.

1988 • 1,016 citations

Casein kinase 2: An ‘eminence grise’ in cellular regulation?

1990 • 920 citations

Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

1994 • 730 citations

High-Efficiency Transformation of Mammalian Cells by Plasmid DNA

1987 • 729 citations

Viral myb oncogene encodes a sequence-specific DNA-binding activity

1988 • 608 citations

New light on Myc and Myb. Part II. Myb.

1990 • 487 citations

Solution structure of a specific DNA complex of the Myb DNA-binding domain with cooperative recognition helices

1994 • 484 citations

The v-myb oncogene product binds to and activates the promyelocyte-specific mim-1 gene

1989 • 460 citations

Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity

1992 • 387 citations

Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation

1990 • 355 citations

PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells.

1994 • 315 citations

Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb

1989 • 302 citations

Myc oncoproteins are phosphorylated by casein kinase II.

1989 • 287 citations

Myb and NF-M: combinatorial activators of myeloid genes in heterologous cell types.

1993 • 275 citations

Casein kinases: pleiotropic mediators of cellular regulation

1993 • 264 citations

Isolation of human cDNA clones ofmyb-related genes, A-myband B-myb

1988 • 222 citations

Synergistic activation of the chicken mim-1 gene by v-myb and C/EBP transcription factors.

1993 • 198 citations

The NF-M transcription factor is related to C/EBP beta and plays a role in signal transduction, differentiation and leukemogenesis of avian myelomonocytic cells.

1993 • 195 citations

Nucleotide sequence of cDNA clones of the murine myb proto-oncogene.

1985 • 174 citations

Dominant interfering alleles define a role for c-Myb in T-cell development.

1994 • 172 citations

Casein kinase II in signal transduction and cell cycle regulation

1993 • 170 citations

The highly conserved amino-terminal region of the protein encoded by the v-myb oncogene functions as a DNA-binding domain.

1987 • 162 citations

Myb: a transcriptional activator linking proliferation and differentiation in hematopoietic cells

1992 • 160 citations

Characterization of the sequence-specific interaction of mouse c-myb protein with DNA.

1990 • 159 citations

c-myc and c-myb protein degradation: effect of metabolic inhibitors and heat shock.

1988 • 154 citations

Regulation of the T-cell receptor delta enhancer by functional cooperation between c-Myb and core-binding factors.

1994 • 154 citations

Recognition of specific DNA sequences by the c-myb protooncogene product: role of three repeat units in the DNA-binding domain.

1993 • 150 citations

Specific DNA Binding by c-Myb: Evidence for a Double Helix-Turn-Helix-Related Motif

1991 • 143 citations

Two Modes of c-myb Activation in Virus-Induced Mouse Myeloid Tumors

1986 • 137 citations

Positive autoregulation of c-myb expression via Myb binding sites in the 5' flanking region of the human c-myb gene.

1991 • 130 citations

Expression of the CD4 gene requires a Myb transcription factor.

1992 • 127 citations

c-myb transactivates cdc2 expression via Myb binding sites in the 5'-flanking region of the human cdc2 gene.

1993 • 125 citations

Binding of the c-myb proto-oncogene product to the simian virus 40 enhancer stimulates transcription.

1990 • 122 citations

The myb oncogene

1990 • 117 citations

Rapid induction of B-cell lymphomas: insertional activation of c-myb by avian leukosis virus

1988 • 112 citations

Myb and Ets proteins cooperate in transcriptional activation of the mim-1 promoter.

1992 • 109 citations

Activation of transcription by v-myb: evidence for two different mechanisms.

1989 • 104 citations

trans activation of gene expression by v-myb.

1990 • 100 citations

Autocrine growth induced by kinase type oncogenes in myeloid cells requires AP-1 and NF-M, a myeloid specific, C/EBP-like factor.

1992 • 98 citations

The murine myeloperoxidase promoter contains several functional elements, one of which binds a cell type-restricted transcription factor, myeloid nuclear factor 1 (MyNF1).

1993 • 98 citations

Negative charge at the casein kinase II phosphorylation site is important for transformation but not for Rb protein binding by the E7 protein of human papillomavirus type 16.

1991 • 97 citations

Mitosis-specific phosphorylation of the nuclear oncoproteins Myc and Myb.

1992 • 93 citations

Structure of the protein encoded by the chicken proto-oncogene c-myb.

1986 • 87 citations

Functional analysis of c-Myb protein in T-lymphocytic cell lines shows that it trans-activates the c-myc promoter.

1990 • 85 citations

Regulation of the expression of the hematopoietic stem cell antigen CD34: role of c-myb.

1994 • 84 citations

Identification of casein kinase II phosphorylation sites in Max: effects on DNA-binding kinetics of Max homo- and Myc/Max heterodimers.

1993 • 80 citations

Moloney murine leukemia virus-induced myeloid tumors in adult BALB/c mice: requirement of c-myb activation but lack of v-abl involvement

1987 • 75 citations

Oncogenic truncation of the first repeat of c-Myb decreases DNA binding in vitro and in vivo.

1993 • 73 citations

Drosophila and vertebrate myb proteins share two conserved regions, one of which functions as a DNA-binding domain.

1987 • 71 citations

RAV-1 insertional mutagenesis: disruption of the c-myb locus and development of avian B-cell lymphomas

1989 • 69 citations

Identification and characterization of the protein encoded by the human c-myb proto-oncogene.

1986 • 69 citations

Regulation of casein kinase II by growth factors: a reevaluation.

1994 • 68 citations

Transcriptional activation by human c-myb and v-myb genes.

1990 • 62 citations

PEBP2/CBF, the Murine Homolog of the Human Myeloid AML1 and PEBP2β/CBFβ Proto-oncoproteins, Regulates the Murine Myeloperoxidase and Neutrophil Elastase Genes in Immature Myeloid Cells

1994 • 52 citations

Recognition of specific DNA sequence by the c-myb proto-oncogene product : Role of three repeat units in the DNA-binding domain

1993 • 50 citations

Expression of the CD4 Gene Requires a Myb Transcription Factor

1992 • 50 citations

Increase in specific DNA binding by carboxyl truncation suggests a mechanism for activation of Myb.

1991 • 49 citations

Regulation of the T-cell receptor δ enhancer by functional cooperation between c-Myb and core-binding factors

1994 • 48 citations

Interaction of the v-and c-Myb proteins with regulatory sequences of the human c-myc gene.

1991 • 47 citations

Positive Autoregulation of c-myb Expression Via Myb Binding Sites in the 5' Flanking Region of the Human c-myb Gene

1991 • 44 citations

New sites of proviral integration associated with murine promonocytic leukemias and evidence for alternate modes of c-myb activation

1992 • 43 citations

Regulation of transcription factors c-Myc, Max, and c-Myb by casein kinase II.

1994 • 41 citations

Acute myeloid leukemia induction by amphotropic murine retrovirus (4070A): clonal integrations involve c-myb in some but not all leukemias

1991 • 41 citations

trans Activation of Gene Expression by v-myb

1990 • 38 citations

Two functionally distinct half sites in the DNA‐recognition sequence of the Myb oncoprotein

1994 • 38 citations

Interaction of the Myb protein with specific DNA binding sites.

1992 • 37 citations

c-Myb and v-Myb are differentially phosphorylated by p42mapk in vitro.

1993 • 35 citations

Structure of the Protein Encoded by the Chicken Proto-Oncogene c-myb

1986 • 34 citations

c-myc and c-myb Protein Degradation: Effect of Metabolic Inhibitors and Heat Shock

1988 • 33 citations

The Murine Myeloperoxidase Promoter Contains Several Functional Elements, One of Which Binds a Cell Type-Restricted Transcription Factor, Myeloid Nuclear Factor 1 (MyNF1)

1993 • 27 citations

Oncogenic Truncation of the First Repeat of c-Myb Decreases DNA Binding In Vitro and In Vivo

1993 • 26 citations

The PR264/c-myb connection: expression of a splicing factor modulated by a nuclear protooncogene.

1992 • 23 citations

Molecular cloning, expression and in vitro functional characterization of Myb-related proteins in Xenopus

1992 • 23 citations

Mapping of a small phosphopeptide at the carboxyterminus of the viral myb protein by monoclonal antibodies.

1989 • 17 citations

High affinity DNA binding of native full length c-Myb and differential proteolytic sensitivity of its N- and C-terminal domains.

1995 • 17 citations

Functional Analysis of c-Myb Protein in T-Lymphocytic Cell Lines Shows that It trans-Activates the c-myc Promoter

1990 • 17 citations

c-myb and growth control.

1992 • 17 citations

Regions of the Moloney murine leukemia virus genome specifically related to induction of promonocytic tumors

1990 • 14 citations