Myb: a transcriptional activator linking proliferation and differentiation in hematopoietic cells

A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

1991 • 1,074 citations

A myb gene required for leaf trichome differentiation in Arabidopsis is expressed in stipules

1991 • 626 citations

New light on Myc and Myb. Part II. Myb.

1990 • 487 citations

The v-myb oncogene product binds to and activates the promyelocyte-specific mim-1 gene

1989 • 460 citations

A c- myb Antisense Oligodeoxynucleotide Inhibits Normal Human Hematopoiesis in Vitro

1988 • 439 citations

The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16

1989 • 434 citations

Octamania: The POU factors in murine development

1991 • 373 citations

Delineation of three functional domains of the transcriptional activator encoded by the c-myb protooncogene.

1989 • 342 citations

Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb

1989 • 302 citations

Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an in vitro study relevant to bone marrow purging.

1991 • 214 citations

The tryptophan cluster: a hypothetical structure of the DNA-binding domain of the myb protooncogene product.

1990 • 156 citations

Mutations in v-myb alter the differentiation of myelomonocytic cells transformed by the oncogene

1990 • 147 citations

Role of tryptophan repeats and flanking amino acids in Myb-DNA interactions.

1990 • 146 citations

Specific DNA Binding by c-Myb: Evidence for a Double Helix-Turn-Helix-Related Motif

1991 • 143 citations

Positive autoregulation of c-myb expression via Myb binding sites in the 5' flanking region of the human c-myb gene.

1991 • 130 citations

Expression patterns of myb genes from Antirrhinum flowers.

1991 • 129 citations

The myb oncogene

1990 • 117 citations

Activation of transcription by v-myb: evidence for two different mechanisms.

1989 • 104 citations

Protein truncation is required for the activation of the c-myb proto-oncogene.

1991 • 97 citations

A single point mutation in the v-ets oncogene affects both erythroid and myelomonocytic cell differentiation

1988 • 96 citations

Transformation by carboxyl-deleted Myb reflects increased transactivating capacity and disruption of a negative regulatory domain.

1991 • 92 citations

v-myb and v-ets transform chicken erythroid cells and cooperate both in trans and in cis to induce distinct differentiation phenotypes.

1991 • 90 citations

Proposed structure for the DNA-binding domain of the Myb oncoprotein based on model building and mutational analysis

1991 • 87 citations

Nuclear oncoprotein expression as a function of lineage, differentiation stage, and proliferative status of normal human hematopoietic cells

1989 • 87 citations

Fusion of the nuclear oncoproteins v-Myb and v-Ets is required for the leukemogenicity of E26 virus

1991 • 86 citations

Estrogen-dependent alterations in differentiation state of myeloid cells caused by a v-myb/estrogen receptor fusion protein.

1991 • 83 citations

Stage-related proliferative activity determines c-myb functional requirements during normal human hematopoiesis.

1990 • 77 citations

v-myb dominance over v-myc in doubly transformed chick myelomonocytic cells

1987 • 68 citations

Differentiation of Mouse Erythroleukemia Cells Enhanced by Alternatively Spliced c- myb mRNA

1990 • 63 citations

The Myb DNA-binding domain is highly conserved in Dictyostelium discoideum.

1992 • 60 citations

Transformation by v-myb correlates with trans-activation of gene expression.

1990 • 57 citations

The ets sequence is required for induction of erythroblastosis in chickens by avian retrovirus E26

1989 • 55 citations

Expression patterns of c-myb and of v-myb induced myeloid-1 (mim-1) gene during the development of the chick embryo

1992 • 49 citations

Increase in specific DNA binding by carboxyl truncation suggests a mechanism for activation of Myb.

1991 • 49 citations

Interaction of the v-and c-Myb proteins with regulatory sequences of the human c-myc gene.

1991 • 47 citations

Antisense myb inhibition of purified erythroid progenitors in development and differentiation is linked to cycling activity and expression of DNA polymerase alpha

1991 • 44 citations

Activation of cMGF expression is a critical step in avian myeloid leukemogenesis.

1991 • 39 citations

Identification of genes differentially expressed in two types of v-myb-transformed avian myelomonocytic cells.

1992 • 29 citations

The myb and myc nuclear oncogenes as transcriptional activators

1990 • 16 citations

Down-regulated c-myb expression inhibits DNA synthesis of T-leukemia cells in most patients.

1990 • 9 citations

Targets for trans-activation by myb.

1991 • 3 citations