Internalization and degradation of receptor-bound human choriogonadotropin in Leydig tumor cells. Fate of the hormone subunits.

Glycoprotein Hormones: Structure and Function

1981 • 2,296 citations

Coated pits, coated vesicles, and receptor-mediated endocytosis

1979 • 2,073 citations

Binding and Degradation of Low Density Lipoproteins by Cultured Human Fibroblasts

1974 • 1,481 citations

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.

1976 • 1,293 citations

Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells.

1980 • 798 citations

Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling.

1980 • 743 citations

Receptor-mediated endocytosis: insights from the lipoprotein receptor system.

1979 • 701 citations

Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts

1977 • 688 citations

Characterization of Several Clonal Lines of Cultured Ley dig Tumor Cells: Gonadotropin Receptors and Steroidogenic Responses*

1981 • 596 citations

Direct visualization of the binding and internalization of a ferritin conjugate of epidermal growth factor in human carcinoma cells A-431.

1979 • 528 citations

Receptor-Mediated Endocytosis of Hormones in Cultured Cells

1981 • 388 citations

Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts.

1978 • 358 citations

Inhibition of proteolytic degradation of low density lipoprotein in human fibroblasts by chloroquine, concanavalin A, and Triton WR 1339.

1975 • 306 citations

Advanced Techniques in Biological Electron Microscopy

1974 • 276 citations

Intracellular Translocation of Iodine-125-Labeled Insulin: Direct Demonstration in Isolated Hepatocytes

1978 • 220 citations

Mannose-specific endocytosis receptor of alveolar macrophages: demonstration of two functionally distinct intracellular pools of receptor and their roles in receptor recycling.

1982 • 211 citations

Peptide Hormone-Induced Receptor Mobility, Aggregation, and Internalization

1981 • 207 citations

Nature of the Subunits of Human Chorionic Gonadotropin

1971 • 174 citations

Degradation of receptor-bound human choriogonadotropin by murine Leydig tumor cells.

1978 • 165 citations

Intracellular polypeptide hormone receptors. Characterization of insulin binding sites in Golgi fractions from the liver of female rats.

1978 • 123 citations

Structure and Function of the Gonadotropins

1979 • 121 citations

Internalisation of gonadotrophin–receptor complex in ovarian luteal cells

1978 • 114 citations

Inhibition of the degradation of receptor-bound human choriogonadotropin by lysosomotropic agents, protease inhibitors, and metabolic inhibitors

1978 • 87 citations

Removal of the surface-bound human choriogonadotropin results in the cessation of hormonal responses in cultured Leydig tumor cells.

1981 • 80 citations

Receptor-Mediated Binding and Internalization of Toxins and Hormones

1981 • 73 citations

Desensitization to gonadotropins in cultured Leydig tumor cells involves loss of gonadotropin receptors and decreased capacity for steroidogenesis.

1981 • 73 citations

Regulation of Gonadotropin Receptors and Steroidogenesis in Cultured Porcine Leydig Cells*

1982 • 54 citations

Internalization and Degradation of Human Chorionic Gonadotropin in Ovine Luteal Cells: Kinetic Studies*

1981 • 49 citations

Demonstration of a direct effect of inhibitors of the degradation of receptor-bound human choriogonadotropin on the steroidogenic pathway

1978 • 36 citations

Studies on the Receptor for Luteinizing Hormone in a Purified Plasma Membrane Preparation from Rat Ovary*

1980 • 28 citations

Degradation of the subunits of receptor-bound human choriogonadotropin by Leydig tumor cells☆

1980 • 24 citations

Inhibition of the degradation of receptor-bound human choriogonadotropin by leupeptin

1979 • 24 citations

Heterogeneity of polypeptide hormones

1974 • 21 citations

Differential processing of subunits of human chorionic gonadotropin by granulosa cells in vivo.

1980 • 13 citations

Doubly Radioiodinated Luteinizing Hormone: Preparation and Characterization*

1981 • 10 citations

Differential Processing of the Two Subunits of Human Choriogonadotropin by Granulosa Cells. II. In Vivo Studies

1981 • 8 citations

Differential Processing of the Two Subunits of Human Choriogonadotropin (hCG) by Granulosa Cells. I. Preparation and Characterization of Selectively Labeled hCG*

1981 • 6 citations