Exploiting Chemical Libraries, Structure, and Genomics in the Search for Kinase Inhibitors

Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray

1995 • 9,575 citations

Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale

1997 • 4,531 citations

Expression monitoring by hybridization to high-density oligonucleotide arrays

1996 • 2,796 citations

CYCLIN-DEPENDENT KINASES: Engines, Clocks, and Microprocessors

1997 • 2,201 citations

Genome-wide expression monitoring in Saccharomyces cerevisiae

1997 • 990 citations

Strategies for epitope analysis using peptide synthesis

1987 • 887 citations

Inhibition of Cyclin‐Dependent Kinases by Purine Analogues

1994 • 625 citations

Stress signaling in yeast

1995 • 415 citations

Protein kinase activity associated with the product of the yeast cell division cycle gene CDC28.

1985 • 370 citations

C_H…O hydrogen bonding in biology

1997 • 320 citations

Signaling phosphate starvation

1996 • 299 citations

Cell cycle regulted transcription in yeast

1994 • 283 citations

Targeted selection of recombinant clones through gene dosage effects.

1983 • 262 citations

Chemical inhibitors of cyclin-dependent kinases

1996 • 251 citations

Carbon-Carbon Bond-Forming Methods on Solid Support. Utilization of Kenner's "Safety-Catch" Linker

1994 • 207 citations

A Family of Cyclin-Like Proteins That Interact with the Pho85 Cyclin-Dependent Kinase

1997 • 199 citations

A common denominator linking glycogen metabolism, nuclear oncogenes and development

1991 • 138 citations

CVT-313, a Specific and Potent Inhibitor of CDK2 That Prevents Neointimal Proliferation

1997 • 138 citations

Starting the cell cycle: what's the point?

1995 • 127 citations

A Structure-Based Library Approach to Kinase Inhibitors

1996 • 125 citations

Combinatorial synthesis of 2,9-substituted purines

1997 • 86 citations

Changes in gene expression in the Ras/adenylate cyclase system of Saccharomyces cerevisiae: correlation with cAMP levels and growth arrest.

1993 • 80 citations

Deletion of the Gene Encoding the Cyclin-Dependent Protein Kinase Pho85 Alters Glycogen Metabolism in Saccharomyces cerevisiae

1996 • 72 citations

Transcription of histone H4, H3, and H1 cell cycle genes: promoter factor HiNF-D contains CDC2, cyclin A, and an RB-related protein.

1994 • 64 citations

The Alkylation of 2-Amino-6-chloropurine with Alcohols by Mitsunobu Reaction for a Synthesis of Carbocyclic Guanosine Analogs

1993 • 27 citations

Elevated expression of stress response genes resulting from deletion of the PHO85 gene

1997 • 27 citations

Signaling phosphate starvation

1996 • 1 citations