Combinatorial synthesis of 2,9-substituted purines

Inhibition of Cyclin‐Dependent Kinases by Purine Analogues

1994 • 625 citations

Preparation and application of the 5-(4-(9-fluorenylmethyloxycarbonyl)aminomethyl-3,5-dimethoxyphenoxy)-valeric acid (PAL) handle for the solid-phase synthesis of C-terminal peptide amides under mild conditions

1990 • 319 citations

Multiple modes of ligand recognition: Crystal structures of cyclin‐dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine

1995 • 273 citations

A Structure-Based Library Approach to Kinase Inhibitors

1996 • 125 citations

Regioselective Preparation of 4-Formyl-3,5-dimethoxyphenol, an Intermediate in the Synthesis of the PAL Solid-Phase Peptide Synthesis Handle

1991 • 33 citations

The Alkylation of 2-Amino-6-chloropurine with Alcohols by Mitsunobu Reaction for a Synthesis of Carbocyclic Guanosine Analogs

1993 • 27 citations