rpoB -Based Microbial Community Analysis Avoids Limitations Inherent in 16S rRNA Gene Intraspecies Heterogeneity

Application of denaturing gradient gel electrophoresis (DGGE) and temperature gradient gel electrophoresis (TGGE) in microbial ecology.

1998 • 2,066 citations

Determination of microbial diversity in environmental samples: pitfalls of PCR-based rRNA analysis

1997 • 2,046 citations

Bias caused by template annealing in the amplification of mixtures of 16S rRNA genes by PCR

1996 • 1,850 citations

Bias in Template-to-Product Ratios in Multitemplate PCR

1998 • 1,454 citations

Sequence heterogeneities of genes encoding 16S rRNAs in Paenibacillus polymyxa detected by temperature gradient gel electrophoresis

1996 • 1,370 citations

Effect of genome size and rrn gene copy number on PCR amplification of 16S rRNA genes from a mixture of bacterial species

1995 • 711 citations

rpoB sequence analysis as a novel basis for bacterial identification

1997 • 493 citations

Novel techniques for analysing microbial diversity in natural and perturbed environments

1998 • 476 citations

Identification of Mycobacterial Species by Comparative Sequence Analysis of the RNA Polymerase Gene ( rpoB )

1999 • 401 citations

Effect of Phenylurea Herbicides on Soil Microbial Communities Estimated by Analysis of 16S rRNA Gene Fingerprints and Community-Level Physiological Profiles

1999 • 385 citations

Frequency of formation of chimeric molecules as a consequence of PCR coamplification of 16S rRNA genes from mixed bacterial genomes

1997 • 333 citations

Seasonal distributions of dominant 16S rRNA-defined populations in a hot spring microbial mat examined by denaturing gradient gel electrophoresis

1997 • 321 citations

Assessment of bacterial community structure in soil by polymerase chain reaction and denaturing gradient gel electrophoresis.

1999 • 318 citations

Changes in Bacterial and Eukaryotic Community Structure after Mass Lysis of Filamentous Cyanobacteria Associated with Viruses

1999 • 314 citations

Prokaryotic Genome Size and SSU rDNA Copy Number: Estimation of Microbial Relative Abundance from a Mixed Population

1999 • 311 citations

Quantifying Microbial Diversity: Morphotypes, 16S rRNA Genes, and Carotenoids of Oxygenic Phototrophs in Microbial Mats

1999 • 275 citations

Intraspecific Variation in Small-Subunit rRNA Sequences in GenBank: Why Single Sequences May Not Adequately Represent Prokaryotic Taxa

1995 • 271 citations

Detection of shifts in microbial community structure and diversity in soil caused by copper contamination using amplified ribosomal DNA restriction analysis

2006 • 270 citations

Identification of a Novel Group of Bacteria in Sludge from a Deteriorated Biological Phosphorus Removal Reactor

1999 • 245 citations

Widespread Archaea and novel Bacteria from the deep sea as shown by 16S rRNA gene sequences

1997 • 238 citations

Detritus-Dependent Development of the Microbial Community in an Experimental System: Qualitative Analysis by Denaturing Gradient Gel Electrophoresis

1999 • 234 citations

Biased 16S rDNA PCR amplification caused by interference from DNA flanking the template region

1998 • 226 citations

Recognition of chimeric small-subunit ribosomal DNAs composed of genes from uncultivated microorganisms

1994 • 215 citations

Two Distinct Mechanisms Cause Heterogeneity of 16S rRNA

1999 • 158 citations

Spatial Heterogeneity of Bacterial Populations along an Environmental Gradient at a Shallow Submarine Hydrothermal Vent near Milos Island (Greece)

1999 • 152 citations

Patterns of sequence variation in two regions of the 16S rRNA multigene family of Escherichia coli

1999 • 73 citations

Analysis of bacterial communities on historical glass by denaturing gradient gel electrophoresis of PCR-amplified gene fragments coding for 16S rRNA

1999 • 65 citations

Analysis of the ' Subunit of DNA-Dependent RNA Polymerase Does Not Support the Hypothesis Inferred from 16S rRNA Analysis that Oenococcus oeni (Formerly Leuconostoc oenos) Is a Tachytelic (Fast-Evolving) Bacterium

1996 • 51 citations

Application of temperature-gradient gel electrophoresis in taxonomy of coryneform bacteria

1999 • 35 citations

Polymerase evolution and organism evolution

1992 • 20 citations