Class II-Associated Invariant Chain Peptide Expression on Myeloid Leukemic Blasts Predicts Poor Clinical Outcome

Acute Myeloid Leukemia

1999 • 1,211 citations

HLA-DM induces clip dissociation from MHC class II αβ dimers and facilitates peptide loading

1995 • 684 citations

Intracellular transport of class II MHC molecules directed by invariant chain

1990 • 548 citations

H2-M Mutant Mice Are Defective in the Peptide Loading of Class II Molecules, Antigen Presentation, and T Cell Repertoire Selection

1996 • 331 citations

The role of MHC class II-restricted tumor antigens and CD4+ T cells in antitumor immunity

2001 • 270 citations

Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II.

1995 • 186 citations

The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancy.

1994 • 184 citations

Major histocompatibility complex class II-transfected tumor cells present endogenous antigen and are potent inducers of tumor-specific immunity

1997 • 168 citations

Nonclassical MHC Class II Molecules

2000 • 148 citations

The antigen-processing mutant T2 suggests a role for MHC-linked genes in class II antigen presentation.

1992 • 125 citations

Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis

2003 • 113 citations

Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis

2003 • 107 citations

Modulation of the Major Histocompatibility Complex Class II–Associated Peptide Repertoire by Human Histocompatibility Leukocyte Antigen (Hla)-Do

2000 • 89 citations

Germinal Center B Cells Regulate Their Capability to Present Antigen by Modulation of HLA-DO

2002 • 80 citations

Regulated Expression of Human Histocompatibility Leukocyte Antigen (HLA)-DO During Antigen-dependent and Antigen-independent Phases of B Cell Development

2002 • 79 citations

Tumor Cells Present MHC Class II-Restricted Nuclear and Mitochondrial Antigens and Are the Predominant Antigen Presenting Cells In Vivo

2000 • 65 citations

Activation of Tumor-specific CD4+ T Lymphocytes by Major Histocompatibility Complex Class II Tumor Cell Vaccines

2004 • 50 citations

Expression and induction of costimulatory and adhesion molecules on acute myeloid leukemic cells

2000 • 45 citations

Expression of co‐stimulatory and adhesion molecules and chemokine or apoptosis receptors on acute myeloid leukaemia: high CD40 and CD11a expression correlates with poor prognosis

2001 • 45 citations

In Vivo and In Vitro Modulation of HLA-DM and HLA-DO Is Induced by B Lymphocyte Activation

2001 • 38 citations

Dendritic cells stimulate the expansion of PML-RAR alpha specific cytotoxic T-lymphocytes: its applicability for antileukemia immunotherapy.

1999 • 34 citations

Cancer immunotherapy by antisense suppression of Ii protein in MHC-class-II-positive tumor cells

1999 • 24 citations