Characterization of the Golgi Complex Cleared of Proteins in Transit and Examination of Calcium Uptake Activities

THE USE OF LEAD CITRATE AT HIGH pH AS AN ELECTRON-OPAQUE STAIN IN ELECTRON MICROSCOPY

1963 • 24,942 citations

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

1990 • 3,250 citations

Stereological Principles for Morphometry in Electron Microscopic Cytology

1969 • 1,969 citations

Polyacrylamide Gel Electrophoresis of Viral Proteins

1971 • 1,477 citations

Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps.

1991 • 1,282 citations

CORRELATED MORPHOMETRIC AND BIOCHEMICAL STUDIES ON THE LIVER CELL

1969 • 1,134 citations

Ion motive ATPases. I. Ubiquity, properties, and significance to cell function

1987 • 964 citations

ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT LIVER

1974 • 840 citations

Functional comparisons between isoforms of the sarcoplasmic or endoplasmic reticulum family of calcium pumps.

1992 • 649 citations

GOLGI APPARATUS, GERL, AND LYSOSOMES OF NEURONS IN RAT DORSAL ROOT GANGLIA, STUDIED BY THICK SECTION AND THIN SECTION CYTOCHEMISTRY

1971 • 583 citations

β-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the golgi complex, shows homology to β-adaptin

1991 • 489 citations

Milieu-induced, selective aggregation of regulated secretory proteins in the trans-Golgi network.

1991 • 457 citations

GOLGI FRACTIONS PREPARED FROM RAT LIVER HOMOGENATES

1973 • 449 citations

Hepatoma secretory proteins migrate from rough endoplasmic reticulum to Golgi at characteristic rates

1983 • 436 citations

The yeast Ca(2+)-ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution.

1992 • 429 citations

Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic β cell via two distinct site-specific endopeptidases

1988 • 403 citations

Biogenesis: Plasma membrane calcium ATPase: 15 years of work on the purified enzyme ¹

1994 • 403 citations

Molecular cloning of cDNAs from human kidney coding for two alternatively spliced products of the cardiac Ca2+-ATPase gene.

1988 • 374 citations

ISOLATION AND CHARACTERIZATION OF GOLGI MEMBRANES FROM BOVINE LIVER

1969 • 357 citations

Identification, sequencing and expression of an integral membrane protein of the trans-Golgi network (TGN38)

1990 • 355 citations

Energy-dependent calcium sequestration activity in rat liver microsomes.

1975 • 342 citations

Localization and quantification of endoplasmic reticulum Ca(2+)-ATPase isoform transcripts

1995 • 341 citations

Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p

1985 • 301 citations

GOLGI FRACTIONS PREPARED FROM RAT LIVER HOMOGENATES

1973 • 298 citations

A saturable receptor for 32P-inositol-l,4,5-trisphosphate in hepatocytes and neutrophils

1986 • 296 citations

ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT LIVER

1974 • 252 citations

Mitotic Golgi fragments in HeLa cells and their role in the reassembly pathway.

1989 • 242 citations

Mutations in PMR1 suppress oxidative damage in yeast cells lacking superoxide dismutase

1995 • 241 citations

Hepatic Golgi fractions resolved into membrane and content subfractions.

1982 • 235 citations

Isolation of a Golgi-rich fraction from rat liver

1970 • 222 citations

The Effect of Phospholipase A on the Calcium Transport and the Role of Unsaturated Fatty Acids in ATPase Activity of Sarcoplasmic Vesicles

1970 • 202 citations

Fragmentation and partitioning of the Golgi apparatus during mitosis in HeLa cells.

1987 • 181 citations

The endoplasmic reticulum and calcium storage

1990 • 169 citations

MG-160

1989 • 168 citations

Folding and trimerization of clathrin subunits at the triskelion hub

1992 • 157 citations

Condensation-sorting events in the rough endoplasmic reticulum of exocrine pancreatic cells.

1989 • 154 citations

Detergent Influence on Rat‐Liver Galactosyltransferase Activities towards Different Acceptors

1977 • 150 citations

Calcium pump isoforms: Diversity, selectivity and plasticity

1992 • 149 citations

The calcium pump of the liver nuclear membrane is identical to that of endoplasmic reticulum.

1992 • 143 citations

A cytosolic complex of p62 and rab6 associates with TGN38/41 and is involved in budding of exocytic vesicles from the trans-Golgi network

1993 • 133 citations

Detection of isoform 4 of the plasma membrane calcium pump in human tissues by using isoform-specific monoclonal antibodies

1996 • 130 citations

Characterization of secretory protein translocation: ribosome-membrane interaction in endoplasmic reticulum.

1986 • 121 citations

Identification of a 200-kD, brefeldin-sensitive protein on Golgi membranes

1992 • 120 citations

Calcium sequestration in the golgi apparatus of cultured mammalian cells revealed by laser scanning confocal microscopy and ion microscopy

1991 • 119 citations

Membranes of mammary gland

1975 • 116 citations

Properties of a reconstituted calcium pump.

1975 • 111 citations

Molecular cloning and tissue distribution of alternatively spliced mRNAs encoding possible mammalian homologs of the yeast secretory pathway calcium pump

1992 • 111 citations

Intracellular and transcellular transport of secretory component and albumin in rat hepatocytes.

1983 • 100 citations

ISOLATION OF THE GOLGI APPARATUS FROM PLANT CELLS

1964 • 94 citations

Exocytic transport vesicles generated in vitro from the trans-Golgi network carry secretory and plasma membrane proteins.

1990 • 85 citations

Immunohistochemical localization of galactosyltransferase in human fibroblasts and HeLa cells.

1981 • 79 citations

Biochemical Studies of Rat Liver Golgi Apparatus

1978 • 78 citations

Ionic milieu controls the compartment-specific activation of pro-opiomelanocortin processing in AtT-20 cells.

1995 • 74 citations

Calcium signalling mechanisms in endoplasmic reticulum activated by inositol 1,4,5-trisphosphate and GTP

1989 • 73 citations

Biogenesis of the polymeric IgA receptor in rat hepatocytes. I. Kinetic studies of its intracellular forms.

1985 • 72 citations

Elevated cytosolic free Ca²⁺ concentrations and massive Ca²⁺ accumulation within vacuoles, in yeast mutant lacking PMR1, a homolog of Ca²⁺‐ATPase

1996 • 67 citations

Okadaic acid treatment leads to a fragmentation of the trans-Golgi network and an increase in expression of TGN38 at the cell surface

1994 • 67 citations

Identification of pp120, an endogenous substrate for the hepatocyte insulin receptor tyrosine kinase, as an integral membrane glycoprotein of the bile canalicular domain.

1988 • 66 citations

Subcellular fractionation of tissue culture cells

1989 • 61 citations

Golgi fractions from livers of control and ethanol-intoxicated rats. Enzymic and morphologic properties following rapid isolation

1979 • 59 citations

Ca2+ transport and Ca2+-dependent ATP hydrolysis by Golgi vesicles from lactating rat mammary glands

1985 • 58 citations

Monoclonal antibody hfd9 identifies a novel 28 kda integral membrane protein on the Cis-golgi

1995 • 54 citations

Energy-dependent calcium sequestration activity in a Golgi apparatus fraction derived from lactating rat mammary glands

1981 • 45 citations

ATP-dependent calcium transport by a Golgi-enriched membrane fraction from mouse mammary gland

1981 • 43 citations

Two‐dimensional mapping of the endogenous proteins of the rat hepatocyte Golgi complex cleared of proteins in transit

1997 • 35 citations

Unbiased 3-D quantitation of ultrastructure in cell biology

1993 • 35 citations

Mannosyltransferase activities in membranes from various yeast strains

1995 • 33 citations

The molecular size of the calcium-transport ATPase of sarcotubular vesicles estimated from radiation inactivation

1968 • 30 citations

Isolation of highly purified golgi membranes from rat liver Use of clycoheximide in vivo to remove golgi contents

1984 • 23 citations

The atp-dependent concentration of calcium by a golgi apparatus-rich fraction isolated from rat liver

1978 • 22 citations

50 years ago

1977 • 14 citations

cAMP inhibits bud growth in a yeast strain compromised for Ca2+ influx into the Golgi

1996 • 13 citations

The Fao cell. A tissue culture model for lipoprotein synthesis and secretion

1987 • 9 citations

Biochemical aspects of the phosphoinositide signalling system with special reference to the formation of inositol cyclic phosphates and arachidonic acid and metabolites on agonist stimulation

1987 • 4 citations