Pex19p Dampens the p19ARF-p53-p21WAF1 Tumor Suppressor Pathway*

p53, the Cellular Gatekeeper for Growth and Division

1997 • 7,621 citations

ARF Promotes MDM2 Degradation and Stabilizes p53: ARF-INK4a Locus Deletion Impairs Both the Rb and p53 Tumor Suppression Pathways

1998 • 1,584 citations

Role of the INK4a Locus in Tumor Suppression and Cell Mortality

1996 • 1,580 citations

Tumor Suppression at the Mouse INK4a Locus Mediated by the Alternative Reading Frame Product p19

1997 • 1,568 citations

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

1999 • 1,549 citations

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

1995 • 1,500 citations

The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2

1998 • 1,152 citations

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF

1999 • 1,068 citations

Nucleolar Arf sequesters Mdm2 and activates p53

1999 • 937 citations

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

1998 • 906 citations

Association of p19ARF with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53

1999 • 731 citations

P19 ^ARF stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

1999 • 543 citations

The INK4A/ARF locus and its two gene products

1999 • 532 citations

Regulation of a Senescence Checkpoint Response by the E2F1 Transcription Factor and p14^ARF Tumor Suppressor

2000 • 391 citations

p16INK4A and p19ARF act in overlapping pathways in cellular immortalization

2000 • 281 citations

Cooperative Signals Governing ARF-Mdm2 Interaction and Nucleolar Localization of the Complex

2000 • 274 citations

Pex19p, a Farnesylated Protein Essential for Peroxisome Biogenesis

1998 • 197 citations

Independent induction of senescence by p16INK4a and p21CIP1 in spontaneously immortalized human fibroblasts.

1998 • 123 citations

Loss of the ARF tumor suppressor reverses premature replicative arrest but not radiation hypersensitivity arising from disabled atm function.

1999 • 120 citations

p16INK4a and the control of cellular proliferative life span

1999 • 119 citations

Peroxisome biogenesis and peroxisome biogenesis disorders

2000 • 108 citations

Stable DNA-Binding Yeast Vector Allowing High-Bait Expression for Use in the Two-Hybrid System

1997 • 58 citations

Genomic Organization and Molecular Characterization of a Gene Encoding HsPXF, a Human Peroxisomal Farnesylated Protein

1997 • 44 citations

p19ARF prevents G1 cyclin-dependent kinase activation by interacting with MDM2 and activating p53 in mouse fibroblasts

1999 • 37 citations

Sequence of a putative human housekeeping gene (HK33) localized on chromosome 1

1994 • 26 citations