Expression of connective tissue growth factor mRNA in the fibrous stroma of mammary tumors

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Tumors: Wounds That Do Not Heal

1986 • 4,202 citations

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

1986 • 2,499 citations

Growth Factors and Cancer

1991 • 2,044 citations

Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10.

1991 • 878 citations

Stimulation of Fibroblast Cell Growth, Matrix Production, and Granulation Tissue Formation by Connective Tissue Growth Factor

1996 • 754 citations

Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair.

1993 • 706 citations

Control of mammary epithelial differentiation: basement membrane induces tissue-specific gene expression in the absence of cell-cell interaction and morphological polarity.

1991 • 659 citations

Transforming growth factor beta increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability.

1988 • 420 citations

Transforming growth factor-beta 1: histochemical localization with antibodies to different epitopes.

1989 • 378 citations

GROWTH FACTORS AND CANCER

1985 • 352 citations

Immunohistochemical staining for transforming growth factor beta 1 associates with disease progression in human breast cancer.

1992 • 346 citations

Vascular Permeability Factor/Vascular Endothelial Growth Factor: An Important Mediator of Angiogenesis in Malignancy and Inflammation

1995 • 337 citations

Significant Correlation Between Connective Tissue Growth Factor Gene Expression and Skin Sclerosis in Tissue Sections from Patients with Systemic Sclerosis

1995 • 278 citations

Stimulation of granulation tissue formation by platelet-derived growth factor in normal and diabetic rats.

1985 • 277 citations

The oncofetal domain of fibronectin defined by monoclonal antibody FDC-6: its presence in fibronectins from fetal and tumor tissues and its absence in those from normal adult tissues and plasma.

1985 • 242 citations

Immunocytochemical localization of secreted transforming growth factor-beta 1 to the advancing edges of primary tumors and to lymph node metastases of human mammary carcinoma.

1993 • 208 citations

Growth factor messenger RNA expression by human breast fibroblasts from benign and malignant lesions.

1991 • 204 citations

Spatial and temporal patterns of immunoreactive transforming growth factor beta 1, beta 2, and beta 3 during excisional wound repair.

1993 • 176 citations

Transforming growth factor beta1 in ductal carcinoma in situ and invasive carcinomas of the breast

1992 • 154 citations

Altered expression of chondroitin sulfate proteoglycan in the stroma of human colon carcinoma. Hypomethylation of PG-40 gene correlates with increased PG-40 content and mRNA levels.

1990 • 149 citations

Differential regulation of expression of two platelet-derived growth factor receptor subunits by transforming growth factor-β

1989 • 136 citations

Altered proteoglycan gene expression and the tumor stroma

1993 • 127 citations

Localization of basic fibroblast growth factor and transforming growth factor beta 1 in the human mammary gland.

1991 • 123 citations

Tenascin expression in the mouse: in situ localization and induction in vitro by bFGF

1993 • 121 citations

Enhanced expression of neural cell adhesion molecules and tenascin (cytotactin) during wound healing.

1991 • 111 citations

Localization of transforming growth factor-β isotypes in lesions of the human breast

1992 • 107 citations

Synthesis of transforming growth factor-beta 1 by megakaryocytes and its localization to megakaryocyte and platelet alpha-granules

1990 • 106 citations

Alterations in proteoglycan synthesis common to healing wounds and tumors.

1991 • 98 citations

Transforming Growth Factor β1 Regulates Tissue Inhibitor of Metalloproteinases—1 Expression in Differentiated Human Articular Chondrocytes

1994 • 92 citations

Relationship of transforming growth factor β1 to extracellular matrix and stromal infiltrates in invasive breast carcinoma

1994 • 90 citations

Extracellular matrix proteins in colorectal carcinomas. Expression of tenascin and fibronectin isoforms.

1995 • 81 citations

An immunohistochemical study of the extracellular matrix in oral squamous cell carcinoma and its association with invasive and metastatic potential

1994 • 78 citations

A Possible Role for Transforming Growth Factor-β in Systemic Sclerosis

1990 • 76 citations

Transforming growth factor β1 is a powerful modulator of platelet‐derived growth factor action in vascular smooth muscle cells

1992 • 64 citations

TGF alpha and TGF beta expression in mammary carcinoma

1993 • 49 citations

Hypomethylation of the decorin proteoglycan gene in human colon cancer

1991 • 49 citations

A novel model of a metastatic human breast tumour xenograft line

1993 • 43 citations

Differential fibrotic stromal responses of host tissue to low- and high-metastatic cloned Lewis lung carcinoma cells.

1994 • 42 citations

Pathogenesis of Desmoplasia. I. Immunofluorescence Identification and Localization of Some Structural Proteins of Line 1 and Line 10 Guinea Pig Tumors and of Healing Wounds 1,2<xref ref-type="fn" rid="FN2">2</xref>

1984 • 41 citations

Effects of TGF‐β1 (transforming growth factor‐β1) on the cell cycle regulation of human breast adenocarcinoma (MCF‐7) cells

1995 • 40 citations

Collagenases in human breast carcinoma cell lines.

1986 • 35 citations

Unusual growth characteristics of human melanoma xenografts in the nude mouse: a model for desmoplasia, dormancy and progression

1992 • 30 citations

Characterization of mammary-derived growth factor 1 receptors and response in human mammary epithelial cell lines.

1990 • 19 citations

Regulation of tumor-host interactions in breast cancer

1992 • 18 citations

Thymic atrophy induced by murine mammary adenocarcinoma in vivo.

1989 • 14 citations

Immunohistochemical Study of Transforming Growth Factor β, Fibronectin, and Fibronectin Receptor in lnvasive Mammary Carcinomas

1992 • 9 citations

Immunohistochemical study of transforming growth factor β, fibronectin, and fibronectin receptor in invasive mammary carcinomas

1994 • 2 citations