The suppressor gene scl1+ of Saccharomyces cerevisiae is essential for growth

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

The codon adaptation index-a measure of directional synonymous codon usage bias, and its potential applications

1987 • 3,628 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

In Vivo Half-Life of a Protein Is a Function of Its Amino-Terminal Residue

1986 • 1,942 citations

Codon selection in yeast.

1982 • 1,580 citations

Codon usage in yeast: cluster analysis clearly differentiates highly and lowly expressed genes

1986 • 1,148 citations

The helical hydrophobic moment: a measure of the amphiphilicity of a helix

1982 • 1,030 citations

DNA sequence required for efficient transcription termination in yeast

1982 • 1,014 citations

The detection and classification of membrane-spanning proteins

1985 • 854 citations

Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements

1987 • 637 citations

[49] Rapid DNA isolations for enzymatic and hybridization analysis

1980 • 572 citations

A conformational preference parameter to predict helices in integral membrane proteins

1986 • 565 citations

Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae.

1988 • 511 citations

Transcending the impenetrable: How proteins come to terms with membranes

1988 • 471 citations

Conservation of high efficiency promoter sequences inSaccharomyces cerevisiae

1982 • 418 citations

Sequence and structural features associated with translational initiator regions in yeast — a review

1987 • 381 citations

Saturation Mutagenesis of the Yeast his3 Regulatory Site: Requirements for Transcriptional Induction and for Binding by GCN4 Activator Protein

1986 • 352 citations

A yeast silencer contains sequences that can promote autonomous plasmid replication and transcriptional activation

1987 • 332 citations

GCN4 protein, a positive transcription factor in yeast, binds general control promoters at all 5' TGACTC 3' sequences.

1986 • 320 citations

The multidrug resistance gene PDR1 from Saccharomyces cerevisiae.

1987 • 276 citations

Sorting of soluble ER proteins in yeast.

1988 • 270 citations

Identification of silencer binding proteins from yeast: possible roles in SIR control and DNA replication

1987 • 238 citations

Saturation mutagenesis of a yeast his3 "TATA element": genetic evidence for a specific TATA-binding protein.

1988 • 236 citations

Control of ribosomal protein gene expression

1988 • 235 citations

Proteasomes (multi-protease complexes) as 20 S ring-shaped particles in a variety of eukaryotic cells.

1988 • 225 citations

Constitutive and inducible Saccharomyces cerevisiae promoters: evidence for two distinct molecular mechanisms.

1986 • 181 citations

Nucleotide sequence of the SUP2 (SUP35) gene of Saccharomyces cerevisiae

1988 • 176 citations

[5] Kilo-sequencing: Creation of an ordered nest of asymmetric deletions across a large target sequence carried on phage M13

1983 • 169 citations

The yeast H+-ATPase gene is controlled by the promoter binding factor TUF

1989 • 148 citations

Conserved sequences upstream of yeast ribosomal protein genes

1985 • 135 citations

Specific binding of TUF factor to upstream activation sites of yeast ribosomal protein genes.

1987 • 135 citations

SUF12 suppressor protein of yeast

1988 • 118 citations

Identification of two factors which bind to the upstream sequences of a number of nuclear genes coding for mitochondrial proteins and to genetic elements important for cell division in yeast

1988 • 103 citations

The PROS-35 gene encodes the 35 kd protein subunit of Drosophila melanogaster proteasome.

1989 • 89 citations

Structure of the Saccharomyces cerevisiae cell wall

1984 • 87 citations

Cycloheximide-resistant temperature-sensitive lethal mutations of Saccharomyces cerevisiae.

1988 • 73 citations

Isolation of the SUP45 omnipotent suppressor gene of Saccharomyces cerevisiae and characterization of its gene product.

1985 • 65 citations

The signal peptide of the rotavirus glycoprotein VP7 is essential for its retention in the ER as an integral membrane protein

1989 • 63 citations

Expression of chicken egg white lysozyme by Saccharomyces cerevisiae

1985 • 47 citations

Functional characterization of a pyrimidine-rich element in the 5'-noncoding region of the yeast iso-1-cytochrome c gene.

1988 • 29 citations

crl mutants of Saccharomyces cerevisiae resemble both mutants affecting general control of amino acid biosynthesis and omnipotent translational suppressor mutants.

1988 • 27 citations