Sequence and structural features associated with translational initiator regions in yeast — a review

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information

1981 • 3,596 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

In Vivo Half-Life of a Protein Is a Function of Its Amino-Terminal Residue

1986 • 1,942 citations

Codon selection in yeast.

1982 • 1,580 citations

Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes

1981 • 1,265 citations

The molecular biology of the yeast saccharomyces

1982 • 1,165 citations

Codon usage in yeast: cluster analysis clearly differentiates highly and lowly expressed genes

1986 • 1,148 citations

The molecular biology of the yeast saccharomyces: Metabolism and gene expression

1983 • 1,118 citations

Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae

1984 • 955 citations

How do eucaryotic ribosomes select initiation regions in messenger RNA?

1978 • 830 citations

The Molecular Biology of the Yeast Saccharomyces (Metabolism and Gene Expression)

1985 • 712 citations

Multiple upstream AUG codons mediate translational control of GCN4

1986 • 654 citations

Insertion mutagenesis to increase secondary structure within the 5′ noncoding region of a eukaryotic mRNA reduces translational efficiency

1985 • 645 citations

The primary structure of the Saccharomyces cerevisiae gene for alcohol dehydrogenase.

1982 • 558 citations

Point mutations close to the AUG initiator codon affect the efficiency of translation of rat preproinsulin in vivo

1984 • 520 citations

Sequence of a yeast DNA fragment containing a chromosomal replicator and the TRP1 gene

1980 • 511 citations

Assembly of the mitochondrial membrane system. CBP6, a yeast nuclear gene necessary for synthesis of cytochrome b.

1985 • 467 citations

Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae.

1984 • 462 citations

mRNA polyadenylate-binding protein: gene isolation and sequencing and identification of a ribonucleoprotein consensus sequence.

1986 • 455 citations

The nucleotide sequence of a rat 18 S ribosomal ribonucleic acid gene and a proposal for the secondary structure of 18 S ribosomal ribonucleic acid.

1984 • 425 citations

Isolation of the β-tubulin gene from yeast and demonstration of its essential function in vivo

1983 • 409 citations

PEP4 gene of Saccharomyces cerevisiae encodes proteinase A, a vacuolar enzyme required for processing of vacuolar precursors.

1986 • 400 citations

Selection of initiation sites by eucaryotic ribosomes: effect of inserting AUG triplets upstream from the coding sequence for preproinsulin

1984 • 390 citations

Primary structure homology between the product of yeast cell division control gene CDC28 and vertebrate oncogenes

1984 • 354 citations

Nucleotide sequences of STE2 and STE3 , cell type-specific sterile genes from Saccharomyces cerevisiae

1985 • 351 citations

Sequence of the gene for iso-l-cytochrome c in saccharomyces cerevisiae

1979 • 348 citations

Compilation and comparison of the sequence context around the AUG startcodons inSaccharomyces cerevisiaemRNAs

1987 • 334 citations

The HTS1 gene encodes both the cytoplasmic and mitochondrial histidine tRNA synthetases of S. cerevisiae

1986 • 308 citations

Nucleotide sequence and transcriptional mapping of the yeastpet56-his3-dedlgene region

1985 • 290 citations

The sequence of the DNAs coding for the mating-type loci of saccharomyces cerevisiae

1981 • 286 citations

Primary Structure of the Saccharomyces cerevisiae GAL4 Gene

1984 • 276 citations

The S. cerevisiae structural gene for chitin synthase is not required for chitin synthesis in vivo

1986 • 261 citations

The leader peptide of yeast gene CPA1 is essential for the translational repression of its expression

1987 • 259 citations

Nucleotide sequence of the yeast nuclear gene for cytochrome c peroxidase precursor. Functional implications of the pre sequence for protein transport into mitochondria.

1982 • 249 citations

Yeast gene TRP5: structure, function, regulation.

1982 • 245 citations

The isolation, characterization, and sequence of the pyruvate kinase gene of Saccharomyces cerevisiae.

1983 • 243 citations

The nucleotide sequence of the HIS4 region of yeast

1982 • 233 citations

Characterization, cloning and sequence analysis of the CDC25 gene which controls the cyclic AMP level of Saccharomyces cerevisiae.

1986 • 232 citations

Initiation of translation at internal AUG codons in mammalian cells

1984 • 231 citations

Repeated DNA sequences upstream from HIS1 also occur at several other co-regulated genes in Saccharomyces cerevisiae.

1983 • 231 citations

Termination-reinitiation occurs in the translation of mammalian cell mRNAs.

1986 • 213 citations

Nucleotide sequence of the yeast alcohol dehydrogenase II gene.

1983 • 208 citations

Complete sequence of the heat shock-inducible HSP90 gene of Saccharomyces cerevisiae.

1984 • 189 citations

Cycloheximide resistance in yeast: the gene and its portein

1983 • 188 citations

Two Functional α-Tubulin Genes of the Yeast Saccharomyces cerevisiae Encode Divergent Proteins

1986 • 178 citations

The primary structure of theSaccharomyces cerevisiaegene for 3-phosphogrycerate kinase

1982 • 175 citations

The secreted form of invertase in Saccharomyces cerevisiae is synthesized from mRNA encoding a signal sequence.

1983 • 164 citations

Molecular characterization of the CAN1 locus in Saccharomyces cerevisiae. A transmembrane protein without N-terminal hydrophobic signal sequence.

1985 • 161 citations

Structural analysis of the two tandemly repeated acid phosphatase genes in yeast

1984 • 158 citations

Yeast LEU2. Repression of mRNA levels by leucine and primary structure of the gene product.

1984 • 152 citations

Assembly of the mitochondrial membrane system. Characterization of a yeast nuclear gene involved in the processing of the cytochrome b pre-mRNA.

1983 • 152 citations

Isolation and DNA Sequence of ADH3, a Nuclear Gene Encoding the Mitochondrial Isozyme of Alcohol Dehydrogenase in Saccharomyces cerevisiae

1985 • 146 citations

Nucleotide sequence of the yeastILV2gene which encodes acetolactate synthase

1985 • 144 citations

Primary structure of the Saccharomyces cerevisiae GAL4 gene.

1984 • 142 citations

Yeast regulatory gene PPR1

1984 • 141 citations

Codon usage tabulated from the GenBank genetic sequence data

1986 • 140 citations

DNA sequences of yeast H3 and H4 histone genes from two non-allelic gene sets encode identical H3 and H4 proteins

1983 • 139 citations

The sequence of theSaccharomyces cerevisiaegenePH02codes for a regulatory protein with unusual aminoacid composition

1987 • 134 citations

Nucleotide sequence of Saccharomyces cerevisiae genes TRP2 and TRP3 encoding bifunctional anthranilate synthase: indole-3-glycerol phosphate synthase.

1984 • 127 citations

Nucleotide sequence of the tcml gene (ribosomal protein L3) of Saccharomyces cerevisiae

1983 • 126 citations

Molecular characterization of cell cycle gene CDC7 from Saccharomyces cerevisiae.

1986 • 126 citations

The pentafunctional FAS1 gene of yeast: its nucleotide sequence and order of the catalytic domains

1986 • 126 citations

Histone H2B genes of yeast encode two different proteins

1980 • 123 citations

Nucleotide sequence of tworas^Hrelated-genes isolated from the yeastSaccharomyces cerevisiae

1984 • 118 citations

Isolation and DNA sequence of ADH3, a nuclear gene encoding the mitochondrial isozyme of alcohol dehydrogenase in Saccharomyces cerevisiae.

1985 • 115 citations

Structural comparison of yeast ribosomal protein genes

1984 • 115 citations

Structure and function of the yeast URA3 gene differentially regulated expression of hybrid β-galactosidase from overlapping coding sequences in yeast

1983 • 112 citations

Saccharomyces cerevisiae ribosomes recognize non-AUG initiation codons.

1984 • 110 citations

Homologous nucleotide sequences at the 5' termini of messenger RNAs synthesized from the yeast enolase and glyceraldehyde-3-phosphate dehydrogenase gene families. The primary structure of a third yeast glyceraldehyde-3-phosphate dehydrogenase gene.

1983 • 110 citations

Nuclear genes coding the yeast mitochondrial adenosine triphosphatase complex. Primary sequence analysis of ATP2 encoding the F1-ATPase beta-subunit precursor.

1985 • 110 citations

The nucleotide sequence of the yeast ARG4 gene

1984 • 109 citations

Mitochondrial and Nonmitochondrial Citrate Synthases in Saccharomyces cerevisiae Are Encoded by Distinct Homologous Genes

1986 • 109 citations

Two functional alpha-tubulin genes of the yeast Saccharomyces cerevisiae encode divergent proteins.

1986 • 107 citations

Translation of insulin-related polypeptides from messenger RNAs with tandemly reiterated copies of the ribosome binding site

1983 • 105 citations

Nuclear genes encoding the yeast mitochondrial ATPase complex. Analysis of ATP1 coding the F1-ATPase alpha-subunit and its assembly.

1986 • 98 citations

KIN28, a yeast split gene coding for a putative protein kinase homologous to CDC28.

1986 • 96 citations

AnalysIs of the primary structure and promoter function of a pyruvate decarbozylase gene (PDCI) fromSaceharomyces cerevisiae

1986 • 95 citations

The primary structure of the yeast hexokinase PII gene (HXK2) which is responsible for glucose repression

1985 • 94 citations

Glycolytic Gene Expression in Saccharomyces cerevisiae: Nucleotide Sequence of GCR1, Null Mutants, and Evidence for Expression

1986 • 94 citations

Nucleotide sequence of the Saccharomyces cerevisiae CTT1 gene and deduced amino‐acid sequence of yeast catalase T

1986 • 93 citations

Isolation and sequence of the structural gene for cytochrome c oxidase subunit VI from Saccharomyces cerevisiae.

1984 • 92 citations

Glutamine nucleotide sequence of Saccharomyces cerevisiae ADE4 encoding phosphoribosylpyrophosphate amidotransferase.

1984 • 90 citations

Structure of yeast LEU4. The 5' flanking region contains features that predict two modes of control and two productive translation starts.

1986 • 89 citations

RAD3 gene of Saccharomyces cerevisiae: nucleotide sequence of wild-type and mutant alleles, transcript mapping, and aspects of gene regulation.

1985 • 84 citations

Complete nucleotide sequence of the hexokinase PI gene (HXK1) of Saccharomyces cerevisiae

1985 • 83 citations

Characterization of a yeast nuclear gene (MST1) coding for the mitochondrial threonyl-tRNA1 synthetase.

1985 • 82 citations

Yeast carbamyl phosphate synthetase. Structure of the yeast gene and homology to Escherichia coli carbamyl phosphate synthetase.

1983 • 79 citations

Sequence of the small subunit of yeast carbamyl phosphate synthetase and identification of its catalytic domain.

1984 • 76 citations

Structure and organization of two linked ribosomal protein genes in yeast

1984 • 76 citations

Yeast LEU1. Repression of mRNA levels by leucine and relationship of 5'-noncoding region to that of LEU2.

1984 • 74 citations

Nucleotide sequence of theSaccharomyces cerevisiaeMET25 gene

1986 • 74 citations

MSW, a yeast gene coding for mitochondrial tryptophanyl-tRNA synthetase.

1985 • 73 citations

DNA sequence of a mutation in the leader region of the yeast iso-1-cytochrome c mRNA

1981 • 71 citations

DNA Sequence and Transcript Mapping of MOD5: Features of the 5′ Region Which Suggest Two Translational Starts

1987 • 71 citations

RAD7 gene of Saccharomyces cerevisiae: transcripts, nucleotide sequence analysis, and functional relationship between the RAD7 and RAD23 gene products.

1986 • 71 citations

Isolation, physical characterization and expression analysis of theSaccharomyces cerevisiaepositive regulatory genePH04

1986 • 70 citations

Nucleotide sequence of yeast GDH1 encoding nicotinamide adenine dinucleotide phosphate-dependent glutamate dehydrogenase.

1985 • 70 citations

A possible novel interaction between the 3′‐end of 18 S ribosomal RNA and the 5'‐leader sequence of many eukaryotic messenger RNAs

1982 • 69 citations

Sequence of theSaccharomyces cerevisiae PHRIgene and homology of thePHRIphotolyase toE. coliphotolyase

1985 • 68 citations

The nucleotide sequence of the yeastMEL1gene

1985 • 66 citations

Nucleotide sequence of the yeast regulatory geneGAL80

1984 • 66 citations

Mitochondrial and nonmitochondrial citrate synthases in Saccharomyces cerevisiae are encoded by distinct homologous genes.

1986 • 60 citations

Structure of the two genes coding for polypeptide chain elongation factor lα (EF-lα) froni Saccharomyces cerevisiae

1986 • 60 citations

Glycolytic gene expression in Saccharomyces cerevisiae: nucleotide sequence of GCR1, null mutants, and evidence for expression.

1986 • 59 citations

The genes for yeast ribosomal proteins S24 and L46 are adjacent and divergently transcribed

1985 • 58 citations

Primary structure of the nuclear PUT2 gene involved in the mitochondrial pathway for proline utilization in Saccharomyces cerevisiae.

1984 • 57 citations

Assembly of the mitochondrial membrane system. Nucleotide sequence of a yeast nuclear gene (CBP1) involved in 5' end processing of cytochrome b pre-mRNA.

1984 • 55 citations

A yeast ribosomal protein gene whose intron is in the 5' leader.

1984 • 55 citations

Isolation and characterization of the SPT2 gene, a negative regulator of Ty-controlled yeast gene expression.

1985 • 54 citations

Comparative Analysis of the 5′-End Regions of Two Repressible Acid Phosphatase Genes in Saccharomyces cerevisiae

1983 • 52 citations

Nucleotide sequence of the RAD10 gene of Saccharomyces cerevisiae.

1985 • 52 citations

The MET2 gene of Saccharomyces cerevisiae: molecular cloning and nucleotide sequence

1986 • 52 citations

Cloning and characterization of the yeast nuclear gene for subunit 5 of cytochrome oxidase.

1985 • 50 citations

Comparison of two yeast invertase genes: conservation of the upstream regulatory region

1985 • 50 citations

Sequence and expression of the dCMP deaminase gene (DCD1) of Saccharomyces cerevisiae.

1986 • 49 citations

General amino acid control and specific arginine repression in Saccharomyces cerevisiae: physical study of the bifunctional regulatory region of the ARG3 gene.

1985 • 48 citations

Nucleotide sequence of the gene coding for yeast cytoplasmic aspartyl-tRNA synthetase (APS); mapping of the 5′ and 3′ termini of AspRS mRNA

1986 • 48 citations

Cloning and characterization of the gene for the yeast cytoplasmic threonyl-tRNA synthetase

1985 • 46 citations

Nucleotide sequence of the transcriptional initiation region of the yeastGAL7gene

1983 • 46 citations

The RAD2 gene of Saccharomyces cerevisiae: nucleotide sequence and transcript mapping

1985 • 45 citations

Molecular cloning and nucleotide sequence analysis of the Saccharomyces cerevisiae RAD1 gene.

1984 • 43 citations

The molecular characterization of three transcriptional mutations in the yeast iso-2-cytochrome c gene.

1982 • 42 citations

Complete nucleotide sequence of the gene encoding the regulatory subunit of 3′,5′-cyclic AMP-dependent protein kinase from the yeastSaccharomyces cerevisiae

1987 • 40 citations

Saccharomyces cerevisiae CDC8 Gene and Its Product

1984 • 38 citations

Yeast ribosomal protein S33 is encoded by an unspllt gene

1983 • 38 citations

DNA sequence and transcript mapping of MOD5: features of the 5' region which suggest two translational starts.

1987 • 37 citations

The SPS4 gene of Saccharomyces cerevisiae encodes a major sporulation-specific mRNA.

1986 • 36 citations

Primary structure of wild-type and mutant alleles of the PET494 gene of Saccharomyces cerevisiae

1986 • 30 citations

Cloning and characterization of the gene coding for cytoplasmic seryl-tRNA synthetase fromSaccharomyces cerevisiae

1987 • 30 citations

Comparative analysis of the 5'-end regions of two repressible acid phosphatase genes in Saccharomyces cerevisiae.

1983 • 23 citations

Saccharomyces cerevisiae CDC8 gene and its product.

1984 • 21 citations