Neurotrophic factors and neuropathic pain

The capsaicin receptor: a heat-activated ion channel in the pain pathway

1997 • 8,634 citations

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man

1988 • 5,129 citations

Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor

2000 • 3,436 citations

An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat

1992 • 3,001 citations

Textbook of pain

1999 • 2,566 citations

Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence

1993 • 2,006 citations

A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury

1990 • 1,819 citations

Peripheral nerve injury triggers central sprouting of myelinated afferents

1992 • 1,073 citations

A Distinct Subgroup of Small DRG Cells Express GDNF Receptor Components and GDNF Is Protective for These Neurons after Nerve Injury

1998 • 617 citations

Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons

1996 • 583 citations

Myelinated afferents signal the hyperalgesia associated with nerve injury

1988 • 565 citations

Functional regeneration of sensory axons into the adult spinal cord

2000 • 517 citations

Downregulation of Tetrodotoxin-Resistant Sodium Currents and Upregulation of a Rapidly Repriming Tetrodotoxin-Sensitive Sodium Current in Small Spinal Sensory Neurons after Nerve Injury

1997 • 509 citations

Potent Analgesic Effects of GDNF in Neuropathic Pain States

2000 • 506 citations

The Effect of Site and Type of Nerve Injury on Spinal Glial Activation and Neuropathic Pain Behavior

1999 • 435 citations

Neurotrophins: Peripherally and centrally acting modulators of tactile stimulus-induced inflammatory pain hypersensitivity

1999 • 434 citations

Tactile allodynia in the absence of C-fiber activation: altered firing properties of DRG neurons following spinal nerve injury

2000 • 433 citations

The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule

1995 • 427 citations

Brain-Derived Neurotrophic Factor Modulates Nociceptive Sensory Inputs and NMDA-Evoked Responses in the Rat Spinal Cord

1999 • 423 citations

Development of Sensory Neurons in the Absence of NGF/TrkA Signaling In Vivo

2000 • 363 citations

Uninjured C-Fiber Nociceptors Develop Spontaneous Activity and α-Adrenergic Sensitivity Following L₆ Spinal Nerve Ligation in Monkey

1999 • 280 citations

A phase II trial of nerve growth factor for sensory neuropathy associated with HIV infection

2000 • 275 citations

Pathophysiology of damaged nerves in relation to chronic pain

1999 • 269 citations

Mechanical hyperalgesia after an L5 spinal nerve lesion in the rat is not dependent on input from injured nerve fibers

2000 • 269 citations

Signs of neuropathic pain depend on signals from injured nerve fibers in a rat model

1993 • 250 citations

Psychophysical observations on patients with neuropathic pain relieved by a sympathetic block

1989 • 249 citations

Contributions of injured and intact afferents to neuropathic pain in an experimental rat model

1996 • 235 citations

Lack of involvement of capsaicin-sensitive primary afferents in nerve-ligation injury induced tactile allodynia in rats

1999 • 216 citations

Changes in Expression of Two Tetrodotoxin-Resistant Sodium Channels and Their Currents in Dorsal Root Ganglion Neurons after Sciatic Nerve Injury But Not Rhizotomy

2000 • 211 citations

Differential role of GDNF and NGF in the maintenance of two TTX-resistant sodium channels in adult DRG neurons

1999 • 205 citations

Spontaneous activity of axotomized afferent neurons after L5 spinal nerve injury in rats

2000 • 204 citations

Axotomized and Intact Muscle Afferents But No Skin Afferents Develop Ongoing Discharges of Dorsal Root Ganglion Origin after Peripheral Nerve Lesion

2000 • 204 citations

Spinal Nerve Injury Enhances Subthreshold Membrane Potential Oscillations in DRG Neurons: Relation to Neuropathic Pain

2000 • 197 citations

A role for BDNF in mechanosensation

1998 • 194 citations

Progressive tactile hypersensitivity: an inflammation-induced incremental increase in the excitability of the spinal cord

1996 • 180 citations

Axotomy results in major changes in BDNF expression by dorsal root ganglion cells: BDNF expression in large trkB and trkC cells, in pericellular baskets, and in projections to deep dorsal horn and dorsal column nuclei

1999 • 177 citations

The molecular pathophysiology of pain: abnormal expression of sodium channel genes and its contributions to hyperexcitability of primary sensory neurons

1999 • 166 citations

Peripheral Neuropathy with Nucleoside Antiretrovirals

1998 • 163 citations

Injured primary sensory neurons switch phenotype for brain-derived neurotrophic factor in the rat

1999 • 159 citations

Causes and consequences of sympathetic basket formation in dorsal root ganglia

1999 • 152 citations

Neurotrophins Cause a New Sensation

1996 • 136 citations

Neurotrophins and nerve injury in the adult

1996 • 134 citations

Spinal nerve ligation: what to blame for the pain and why

2000 • 130 citations

Increased uptake and transport of cholera toxin B‐subunit in dorsal root ganglion neurons after peripheral axotomy: Possible implications for sensory sprouting

1999 • 130 citations

Tetrodotoxin inhibits neuropathic ectopic activity in neuromas, dorsal root ganglia and dorsal horn neurons

1997 • 123 citations

Synaptic reorganization in the substantia gelatinosa after peripheral nerve neuroma formation: aberrant innervation of lamina II neurons by Abeta afferents.

2000 • 116 citations

Abnormal substance P release from the spinal cord following injury to primary sensory neurons

2000 • 108 citations

NT‐3, but not BDNF, prevents atrophy and death of axotomized spinal cord projection neurons

1998 • 98 citations

NGF but Not NT-3 or BDNF Prevents the A Fiber Sprouting into Lamina II of the Spinal Cord That Occurs Following Axotomy

1996 • 85 citations

Glial cell line derived neurotrophic factor (GDNF) regulates VR1 and substance P in cultured sensory neurons

1999 • 75 citations

Distribution of c-fos expressing dorsal horn neurons after electrical stimulation of low threshold sensory fibers in the chronically injured sciatic nerve

1994 • 62 citations

Neurotrophic factor effects on pain-signaling systems

2000 • 8 citations

Deleted Work

1955 • 0 citations