Contributions of low molecule number and chromosomal positioning to stochastic gene expression

Stochastic Gene Expression in a Single Cell

2002 • 5,397 citations

Global analysis of protein expression in yeast

2003 • 3,790 citations

Transcriptional regulatory code of a eukaryotic genome

2004 • 2,174 citations

Noise in eukaryotic gene expression

2003 • 1,694 citations

Control of Stochasticity in Eukaryotic Gene Expression

2004 • 1,448 citations

Summing up the noise in gene networks

2004 • 1,295 citations

Gene Regulation at the Single-Cell Level

2005 • 1,116 citations

Control, exploitation and tolerance of intracellular noise

2002 • 1,030 citations

Active genes dynamically colocalize to shared sites of ongoing transcription

2004 • 1,023 citations

Characterization of the Yeast Transcriptome

1997 • 941 citations

Noise Propagation in Gene Networks

2005 • 819 citations

A positive-feedback-based bistable ‘memory module’ that governs a cell fate decision

2003 • 742 citations

The evolutionary dynamics of eukaryotic gene order

2004 • 729 citations

Positive feedback in eukaryotic gene networks: cell differentiation by graded to binary response conversion

2001 • 706 citations

Identification and Distinct Regulation of Yeast TATA Box-Containing Genes

2004 • 654 citations

Markovian Modeling of Gene-Product Synthesis

1995 • 645 citations

Genome-Wide Localization of the Nuclear Transport Machinery Couples Transcriptional Status and Nuclear Organization

2004 • 594 citations

Stochastic Gene Expression in Fluctuating Environments

2004 • 547 citations

Ultrasensitivity and noise propagation in a synthetic transcriptional cascade

2005 • 506 citations

Enhancement of cellular memory by reducing stochastic transitions

2005 • 505 citations

Spatiotemporal control of gene expression with pulse-generating networks

2004 • 475 citations

Fundamentally Different Logic of Gene Regulation in Eukaryotes and Prokaryotes

1999 • 472 citations

Prediction and measurement of an autoregulatory genetic module

2003 • 452 citations

Perturbation of Nuclear Architecture by Long-Distance Chromosome Interactions

1996 • 425 citations

Spatial proximity of translocation-prone gene loci in human lymphomas

2003 • 408 citations

Nucleosomes facilitate their own invasion

2004 • 376 citations

Mathematical Models of Chemical Reactions : Theory and Applications of Deterministic and Stochastic Models

1992 • 307 citations

Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression.

1996 • 270 citations

Mathematical Models of Chemical Reactions. Theory and Applications of Deterministic and Stochastic Models

1989 • 264 citations

The Yeast CDK Inhibitor Sic1 Prevents Genomic Instability by Promoting Replication Origin Licensing in Late G1

2002 • 243 citations

Concepts in nuclear architecture

2005 • 241 citations

Efficient Attenuation of Stochasticity in Gene Expression Through Post-transcriptional Control

2004 • 225 citations

Synthetic Gene Network for Entraining and Amplifying Cellular Oscillations

2002 • 210 citations

Conserved homeodomain proteins interact with MADS box protein Mcm1 to restrict ECB-dependent transcription to the M/G1 phase of the cell cycle

2002 • 169 citations

Absolute mRNA levels and transcriptional initiation rates in Saccharomyces cerevisiae.

1996 • 167 citations

Noisy signal amplification in ultrasensitive signal transduction

2004 • 162 citations

Transcript Abundance in Yeast Varies over Six Orders of Magnitude

2002 • 159 citations

Does replication‐induced transcription regulate synthesis of the myriad low copy number proteins of Escherichia coli?

1995 • 150 citations

Modulation of a Transcription Factor Counteracts Heterochromatic Gene Silencing in Drosophila

2001 • 147 citations

Independent regulation of the two Pax5 alleles during B-cell development

1999 • 142 citations

Haploinsufficiency at the Nkx3.1 locus

2003 • 142 citations

Imaging of single light-responsive clock cells reveals fluctuating free-running periods

2005 • 133 citations

Reverse recruitment: The Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation

2005 • 132 citations

Modeling the fission yeast cell cycle: Quantized cycle times in wee1 ⁻ cdc25Δ mutant cells

2000 • 120 citations

Gal80-Gal80 interaction on adjacent Gal4p binding sites is required for complete GAL gene repression

2001 • 71 citations

Evidence for two modes of cooperative DNA binding in vivo that do not involve direct protein–protein interactions

1998 • 67 citations

Fluctuations in transcription factor binding can explain the graded and binary responses observed in inducible gene expression

2003 • 62 citations

Transcriptional enhancers – on/off gene regulation as an adaptation to silencing in higher eukaryotic nuclei

2001 • 32 citations

Cycling without the Cyclosome: Modeling a Yeast Strain Lacking the APC

2004 • 30 citations

Fluctuations and correlations in a diffusion-reaction system: Unified description of internal fluctuations and external noise

1992 • 20 citations

Amplitude control of cell-cycle waves by nuclear import

2004 • 19 citations