A Role for β-Cell-Expressed G Protein-Coupled Receptor 119 in Glycemic Control by Enhancing Glucose-Dependent Insulin Release

Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus.

1993 • 1,579 citations

Dipeptidyl-peptidase IV (CD26)-role in the inactivation of regulatory peptides

1999 • 1,258 citations

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats.

1999 • 1,207 citations

Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-α

2003 • 1,007 citations

Endocannabinoid control of food intake and energy balance

2005 • 734 citations

The Origin and Function of the Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)/Glucagon Superfamily*

2000 • 669 citations

Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents

2006 • 626 citations

Minireview: Glucagon-Like Peptides Regulate Cell Proliferation and Apoptosis in the Pancreas, Gut, and Central Nervous System

2004 • 546 citations

The Origin and Function of the Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)/Glucagon Superfamily

2000 • 354 citations

Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor

2004 • 344 citations

Double Incretin Receptor Knockout (DIRKO) Mice Reveal an Essential Role for the Enteroinsular Axis in Transducing the Glucoregulatory Actions of DPP-IV Inhibitors

2004 • 300 citations

The Role of Sulphonylureas in the Management of Type 2 Diabetes Mellitus

2004 • 299 citations

Gastric Inhibitory Polypeptide and Glucagon-Like Peptide-1 in the Pathogenesis of Type 2 Diabetes

2004 • 208 citations

Carboxyl-terminal mutations of Gq alpha and Gs alpha that alter the fidelity of receptor activation.

1996 • 171 citations

Enhanced glucose-dependent insulinotropic polypeptide secretion and insulinotropic action in glucagon-like peptide 1 receptor -/- mice.

1998 • 161 citations

Therapeutic Approaches to Preserve Islet Mass in Type 2 Diabetes

2006 • 150 citations

A Potent and Highly Selective VPAC2 Agonist Enhances Glucose-Induced Insulin Release and Glucose Disposal

2002 • 121 citations

Glucose-dependent insulinotropic polypeptide receptor null mice exhibit compensatory changes in the enteroinsular axis

2003 • 117 citations

Creation of a constitutively activated state of the 5-hydroxytryptamine2A receptor by site-directed mutagenesis: inverse agonist activity of antipsychotic drugs.

1998 • 93 citations

Treatment of Type 2 diabetes mellitus with agonists of the GLP-1 receptor or DPP-IV inhibitors

2004 • 91 citations

Treatment of Type 2 diabetes mellitus with agonists of the GLP-1 receptor or DPP-IV inhibitors

2004 • 83 citations

Glucagon-Like Peptide-1-Based Therapies for the Treatment of Type 2 Diabetes Mellitus

2005 • 74 citations

The Therapeutic Potential of Inhibitors of Dipeptidyl Peptidase IV (DPP IV) and Related Proline-Specific Dipeptidyl Aminopeptidases

2005 • 74 citations

Gut peptides in the treatment of diabetes mellitus

2004 • 28 citations

The use of constitutively active receptors for drug discovery at the G protein-coupled receptor gene pool.

2001 • 21 citations