Role of G Proteins in Calcium Channel Modulation

Multiple types of neuronal calcium channels and their selective modulation

1988 • 1,399 citations

The GTP-binding protein, Go9 regulates neuronal calcium channels

1987 • 910 citations

A novel receptor-operated Ca2+-permeable channel activated by ATP in smooth muscle

1987 • 786 citations

GTP-binding proteins mediate transmitter inhibition of voltage-dependent calcium channels

1986 • 666 citations

Neurotransmitters decrease the calcium conductance activated by depolarization of embryonic chick sensory neurones.

1981 • 555 citations

A G Protein Directly Regulates Mammalian Cardiac Calcium Channels

1987 • 551 citations

Synergism of inositol trisphosphate and tetrakisphosphate in activating Ca2+-dependent K+ channels

1987 • 529 citations

Regulation of calcium influx by second messengers in rat mast cells

1988 • 506 citations

Enhancement of calcium current in Aplysia neurones by phorbol ester and protein kinase C

1985 • 476 citations

Purified dihydropyridine-binding site from skeletal muscle t-tubules is a functional calcium channel

1986 • 405 citations

Voltage-activated calcium channels that must be phosphorylated to respond to membrane depolarization.

1987 • 393 citations

Noradrenaline contracts arteries by activating voltage-dependent calcium channels

1988 • 340 citations

Effects of dopamine and noradrenaline on Ca channels of cultured sensory and sympathetic neurons of chick

1986 • 316 citations

Kinase C activator 1,2-oleoylacetylglycerol attenuates voltage-dependent calcium current in sensory neurons.

1986 • 313 citations

The G protein-gated atrial K+ channel is stimulated by three distinct GIα-subunits

1988 • 306 citations

Dynorphin A selectively reduces a large transient (N-type) calcium current of mouse dorsal root ganglion neurons in cell culture.

1987 • 266 citations

Effects of protein kinase C activators on cardiac Ca2+ channels

1988 • 264 citations

Calcium‐dependent currents in cultured rat dorsal root ganglion neurones are inhibited by an adenosine analogue.

1986 • 256 citations

cGMP phosphodiesterase of retinal rods is regulated by two inhibitory subunits.

1988 • 246 citations

Guanine nucleotide-binding protein Go-induced coupling of neuropeptide Y receptors to Ca2+ channels in sensory neurons.

1988 • 242 citations

Newly Identified Brain Potassium Channels Gated by the Guanine Nucleotide Binding Protein G _o

1988 • 236 citations

Ca channels in adrenal glomerulosa cells: K+ and angiotensin II increase T-type Ca channel current.

1988 • 193 citations

Bradykinin-activated transmembrane signals are coupled via No or Ni to production of inositol 1,4,5-trisphosphate, a second messenger in NG108-15 neuroblastoma-glioma hybrid cells.

1986 • 182 citations

Evidence that agonists stimulate bivalent-cation influx into human endothelial cells

1988 • 177 citations

Inositol(1,3,4,5)tetrakisphosphate-induced activation of sea urchin eggs requires the presence of inositol trisphosphate

1987 • 163 citations

cGMP-dependent protein kinase enhances Ca2+ current and potentiates the serotonin-induced Ca2+ current increase in snail neurones

1986 • 154 citations

Regulation of cytosolic calcium by cAMP and cGMP in freshly isolated smooth muscle cells from bovine trachea.

1988 • 147 citations

γ-Aminobutyric acid-induced depression of calcium currents of chick sensory neurons

1985 • 147 citations

Calcium channels in thrombin-activated human platelet membrane

1988 • 136 citations

Noradrenaline modulation of calcium channels in single smooth muscle cells from rabbit ear artery.

1988 • 136 citations

Angiotensin II-induced stimulation of voltage-dependent Ca2+ currents in an adrenal cortical cell line.

1988 • 134 citations

Extracellular ATP induces a large nonselective conductance in macrophage plasma membranes.

1988 • 134 citations

Regulation of calcium currents by a GTP analogue: Potentiation of (−)-baclofen-mediated inhibition

1986 • 130 citations

Inositol trisphosphate isomers, but not inositol 1,3,4,5-tetrakisphosphate, induce calcium influx in Xenopus laevis oocytes.

1988 • 129 citations

Regulation of one type of Ca ²⁺ current in smooth muscle cells by diacylglycerol and acetylcholine

1988 • 106 citations

G_o, a GTP‐Binding Protein: Immunochemical and Immunohistochemical Localization in the Rat

1988 • 105 citations

Cyclic AMP-independent, dual regulation of voltage-dependent Ca2+ currents by LHRH and somatostatin in a pituitary cell line.

1988 • 101 citations

Activation of protein kinase C by cis- and trans-fatty acids and its potentiation by diacylglycerol

1988 • 90 citations

Protein kinase activator 1-oleoyl-2-acetyl-sn-glycerol inhibits two types of calcium currents in GH3 cells

1988 • 84 citations

Opening of dihydropyridine calcium channels in skeletal muscle membranes by inositol trisphosphate

1988 • 80 citations

Activation of soluble guanylate cyclase by arachidonic acid and 15-lipoxygenase products

1986 • 77 citations

Activation of Muscarinic Potassium Currents by ATPγS in Atrial Cells

1988 • 71 citations

GTP-binding proteins mediate acetylcholine inhibition of voltage dependent calcium channels in hippocampal neurons

1989 • 68 citations

Inhibition of adenylate cyclase.

1985 • 65 citations

Guanine nucleotide-binding protein, alpha i-3, directly activates a cation channel in rat renal inner medullary collecting duct cells.

1989 • 62 citations

Patch Clamp Recordings of Single Ion Channel Activation by Gonadotrophin-Releasing Hormone in Ovine Pituitary Gonadotrophs

1986 • 57 citations

Hormonal regulation of pituitary GH₃ cell K⁺ channels by G_k is mediated by its α‐subunit

1987 • 55 citations

Role of a protein regulating guanine nucleotide binding in phosphoinositide breakdown and calcium mobilization by bradykinin in neuroblastoma × glioma hybrid NG108-15 cells: Effects of pertussis toxin and cholera toxin on receptor-mediated signal transduction

1987 • 52 citations

SELECTIVE DEFICIENCY OF GUANINE NUCLEOTIDE-BINDING PROTEIN Go IN TWO DOPAMINE-RESISTANT PITUITARY TUMORS

1988 • 50 citations

Actions of baclofen on components of the Ca‐current in rat and mouse DRG neurones in culture

1988 • 50 citations

Detection of ligand-activated conductive Ca2+ channels in human B lymphocystephen

1988 • 49 citations

Angiotensin II increases Isi and blocks IK in single aortic cell of rabbit

1988 • 40 citations

Tyrosine protein kinase activity of the EGF receptor is required to induce activation of receptor-operated calcium channels

1989 • 36 citations

Differential blocking action of synthetic ω-conotoxin on components of Ca2+ channel current in clonal GH3 cells

1987 • 33 citations

The role of guanyl nucleotide binding proteins in the formation of inositol phosphates in adrenal glomerulosa cells

1986 • 33 citations

Secretion‐stimulating and secretion‐inhibiting hormones stimulate high‐affinity pertussis‐toxin‐sensitive GTPases in membranes of a pituitary cell line

1989 • 26 citations

Regulation of receptor-mediated calcium influx across the plasma membrane in a human leukemic T-cell line: evidence of its dependence on an initial calcium mobilization from intracellular stores

1988 • 23 citations

Involvement of the guanine nucleotide-binding protein, No, in the inhibitory regulation of neuronal calcium channels.

1988 • 13 citations

Pertussis toxin pretreatment abolishes dihydropyridine inhibition of calcium flux in the 235-1 pituitary cell line

1988 • 10 citations