Activation of Muscarinic Potassium Currents by ATPγS in Atrial Cells

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

1984 • 1,300 citations

NUCLEOSIDE PHOSPHOROTHIOATES

1985 • 830 citations

Uncoupling of cardiac muscarinic and β-adrenergic receptors from ion channels by a guanine nucleotide analogue

1985 • 527 citations

Direct Activation of Mammalian Atrial Muscarinic Potassium Channels by GTP Regulatory Protein G _k

1987 • 441 citations

On the mechanism of ?-adrenergic regulation of the Ca channel in the guinea-pig heart

1985 • 396 citations

Guanosine 5'-O-(2-thiodiphosphate). An inhibitor of adenylate cyclase stimulation by guanine nucleotides and fluoride ions.

1979 • 382 citations

Reconstitution of resolved muscarinic cholinergic receptors with purified GTP-binding proteins.

1985 • 314 citations

Modulation of Ca current during the phosphorylation cycle in the guinea pig heart

1986 • 254 citations

Dependence of an adenosine-activated potassium current on a GTP-binding protein in mammalian central neurons

1987 • 254 citations

Synthesis and properties of diastereoisomers of adenosine 5'-(O-1-thiotriphosphate) and adenosine 5'-(O-2-thiotriphosphate)

1976 • 214 citations

Mechanism of muscarinic receptor-induced K+ channel activation as revealed by hydrolysis-resistant GTP analogues.

1988 • 205 citations

Regulation of the cardiac calcium channel by protein phosphatases

1987 • 143 citations

Adenosine 5'-phosphorothioate. A nucleotide analog that is a substrate, competitive inhibitor, or regulator of some enzymes that interact with adenosine 5'-phosphate

1968 • 138 citations

Short-term desensitization of muscarinic K+ channel current in isolated atrial myocytes and possible role of GTP-binding proteins

1987 • 100 citations

The enzymatic synthesis of thiophosphate analogs of nucleotides

1972 • 90 citations

Stereochemical courses of nucleotidyltransferase and phosphotransferase action. Uridine diphosphate glucose pyrophosphorylase, galactose-1-phosphate uridylyltransferase, adenylate kinase, and nucleoside diphosphate kinase

1979 • 72 citations

Interaction of retinal transducin with guanosine triphosphate analog: specificity of the .gamma.-phosphate binding region

1986 • 50 citations

A quantitative analysis of the acetylcholine-activated potassium current in single cells from frog atrium

1987 • 40 citations

Nucleoside diphosphokinase from beef heart cytosol. I. Physical and kinetic properties

1972 • 34 citations

Substrate specificity and kinetic mechanism of human placental insulin receptor/kinase

1987 • 31 citations

Quinidine inhibition of the muscarine receptor-activated K+ channel current in atrial cells of guinea pig

1987 • 27 citations

Physiological correlation between nucleoside-diphosphate kinase and the enzyme-associated guanine nucleotide binding proteins

1987 • 21 citations

Role of the sodium pump and the background K+ channel in passive K+(Rb+) uptake by isolated cardiac sarcolemmal vesicles

1988 • 6 citations