Increased Expression of Brain-Derived Neurotrophic Factor Induces Formation of Basal Dendrites and Axonal Branching in Dentate Granule Cells in Hippocampal Explant Cultures

Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats

1965 • 3,461 citations

A simple method for organotypic cultures of nervous tissue

1991 • 3,075 citations

A permanent change in brain function resulting from daily electrical stimulation

1969 • 3,056 citations

Dendritic organization in the neurons of the visual and motor cortices of the cat.

1953 • 2,180 citations

Studies on the structure of the cerebral cortex. II. Continuation of the study of the ammonic system.

1934 • 1,982 citations

Dentate Granule Cell Neurogenesis Is Increased by Seizures and Contributes to Aberrant Network Reorganization in the Adult Rat Hippocampus

1997 • 1,880 citations

Mossy fiber synaptic reorganization in the epileptic human temporal lobe

1989 • 1,150 citations

Evidence of functional mossy fiber sprouting in hippocampal formation of kainic acid-treated rats

1985 • 1,101 citations

Trk receptors: mediators of neurotrophin action

2001 • 1,051 citations

Synaptic Reorganization in the Hippocampus Induced by Abnormal Functional Activity

1988 • 912 citations

Migration and distribution of two populations of hippocampal granule cell precursors during the perinatal and postnatal periods

1990 • 805 citations

Synaptic reorganization by mossy fibers in human epileptic fascia dentata

1991 • 666 citations

Limbic Seizures Increase Neuronal Production of Messenger RNA for Nerve Growth Factor

1989 • 624 citations

Granule cell dispersion in the dentate gyrus of humans with temporal lobe epilepsy

1990 • 604 citations

Granule-Like Neurons at the Hilar/CA3 Border after Status Epilepticus and Their Synchrony with Area CA3 Pyramidal Cells: Functional Implications of Seizure-Induced Neurogenesis

2000 • 598 citations

Expression of brain-derived neurotrophic factor protein in the adult rat central nervous system

1997 • 500 citations

A light and electron microscopic analysis of the mossy fibers of the rat dentate gyrus

1986 • 489 citations

Mosaic organization of the hippocampal neuroepithelium and the multiple germinal sources of dentate granule cells

1990 • 395 citations

Selective reinnervation of hippocampal area CA1 and the fascia dentata after destruction of CA3-CA4 afferents with kainic acid

1980 • 380 citations

Electrographic Seizures and New Recurrent Excitatory Circuits in the Dentate Gyrus of Hippocampal Slices from Kainate-Treated Epileptic Rats

1996 • 361 citations

Destabilization of Cortical Dendrites and Spines by BDNF

1999 • 352 citations

Hippocampal mossy fiber sprouting and synapse formation after status epilepticus in rats: Visualization after retrograde transport of biocytin

1995 • 339 citations

BDNF Protein Measured by a Novel Enzyme Immunoassay in Normal Brain and after Seizure: Partial Disagreement with mRNA Levels

1995 • 328 citations

Brain-derived neurotrophic factor transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex

1999 • 306 citations

Inhibition of Dentate Granule Cell Neurogenesis with Brain Irradiation Does Not Prevent Seizure-Induced Mossy Fiber Synaptic Reorganization in the Rat

1999 • 288 citations

Developmental and mature expression of full-length and truncated TrkB, receptors in the rat forebrain

1996 • 281 citations

Truncated and full-length TrkB receptors regulate distinct modes of dendritic growth

2000 • 278 citations

Suppressed Epileptogenesis in BDNF Mutant Mice

1995 • 272 citations

Physiologic and Morphologic Characteristics of Granule Cell Circuitry in Human Epileptic Hippocampus

1995 • 270 citations

Status epilepticus-induced hilar basal dendrites on rodent granule cells contribute to recurrent excitatory circuitry

2000 • 242 citations

Structure of the granular layer of the rat dentate gyrus. A light microscopic and Golgi study.

1981 • 240 citations

Quantitative, three‐dimensional analysis of granule cell dendrites in the rat dentate gyrus

1990 • 235 citations

Seizure-Induced Changes in Neurotrophin Expression: Implications for Epilepsy

1993 • 229 citations

Brain-derived neurotrophic factor restores long-term potentiation in polysialic acid-neural cell adhesion molecule-deficient hippocampus

2000 • 210 citations

Regulation of brain-derived neurotrophic factor (BDNF) expression and release from hippocampal neurons is mediated by non-NMDA type glutamate receptors

1994 • 210 citations

Regulation of neurotrophin receptor expression during embryonic and postnatal development

1994 • 208 citations

Regulated neurotrophin receptor responsiveness during neuronal migrationand early differentiation

1994 • 207 citations

Spontaneous Limbic Seizures after Intrahippocampal Infusion of Brain-Derived Neurotrophic Factor

2002 • 201 citations

Lesion‐induced mossy fibers to the molecular layer of the rat fascia dentata: Identification of postsynaptic granule cells by the Golgi‐EM technique

1983 • 193 citations

Functional anatomy of limbic seizures: Focal discharges from medial entorhinal cortex in rat

1983 • 192 citations

Immunohistochemical Evidence of Seizure-Induced Activation of trk Receptors in the Mossy Fiber Pathway of Adult Rat Hippocampus

1999 • 189 citations

The persistent expression of a highly polysialylated NCAM in the dentate gyrus of the adult rat

1991 • 188 citations

PSA‐NCAM modulates BDNF‐dependent survival and differentiation of cortical neurons

2001 • 185 citations

In Vivo Intracellular Analysis of Granule Cell Axon Reorganization in Epileptic Rats

1999 • 181 citations

Excitatory Synaptic Input to Granule Cells Increases With Time After Kainate Treatment

2001 • 177 citations

Dentate granule cells form novel basal dendrites in a rat model of temporal lobe epilepsy

1998 • 172 citations

Selective Inhibition of Kindling Development by Intraventricular Administration of TrkB Receptor Body

1999 • 165 citations

The effects of growth factors on the survival and differentiation of cultured dentate gyrus neurons.

1996 • 161 citations

Recurrent Excitatory Connectivity in the Dentate Gyrus of Kindled and Kainic Acid–Treated Rats

2000 • 151 citations

Endogenous BDNF Protein Is Increased in Adult Rat Hippocampus after a Kainic Acid Induced Excitotoxic Insult but Exogenous BDNF Is Not Neuroprotective

1998 • 144 citations

The effects of growth factors on the survival and differentiation of cultured dentate gyrus neurons

1996 • 140 citations

Kindling is associated with the formation of novel mossy fibre synapses in the CA3 region

1992 • 140 citations

Recurrent Mossy Fiber Pathway in Rat Dentate Gyrus: Synaptic Currents Evoked in Presence and Absence of Seizure-Induced Growth

1999 • 131 citations

Patients with temporal lobe epilepsy show an increase in brain-derived neurotrophic factor protein and its correlation with neuropeptide Y

1999 • 127 citations

The Structure of Ammon's Horn.

1969 • 126 citations

Mossy Fiber–Granule Cell Synapses in the Normal and Epileptic Rat Dentate Gyrus Studied With Minimal Laser Photostimulation

1999 • 120 citations

Enhanced Propagation of Epileptiform Activity Through the Kindled Dentate Gyrus

1998 • 119 citations

Anterograde transport of endogenous brain-derived neurotrophic factor in hippocampal mossy fibers

1997 • 119 citations

Kainic acid-induced mossy fiber sprouting and synapse formation in the dentate gyrus of rats

2000 • 117 citations

Temporal and spacial relationships between PSA-NCAM-expressing, newly generated granule cells, and radial glia-like cells in the adult dentate gyrus

1999 • 114 citations

Ultrastructural features and synaptic connections of hilar ectopic granule cells in the rat dentate gyrus are different from those of granule cells in the granule cell layer

2001 • 112 citations

Selective enhancement of axonal branching of cultured dentate gyrus neurons by neurotrophic factors

1995 • 110 citations

Dynamic changes of brain-derived neurotrophic factor protein levels in the rat forebrain after single and recurring kindling-induced seizures

1998 • 107 citations

Brain-derived neurotrophic factor immunoreactivity in the limbic system of rats after acute seizures and during spontaneous convulsions: temporal evolution of changes as compared to neuropeptide Y

1999 • 104 citations

Decreased BDNF signalling in transgenic mice reduces epileptogenesis

2002 • 104 citations

Altered mRNA expression for brain-derived neurotrophic factor and type II calcium/Calmodulin-dependent protein kinase in the hippocampus of patients with intractable temporal lobe epilepsy

2000 • 100 citations

Granule cell mRNA levels for BDNF, NGF, and NT-3 correlate with neuron losses or supragranular mossy fiber sprouting in the chronically damaged and epileptic human hippocampus

1997 • 100 citations

Immunohistochemical Evidence of Seizure-Induced Activation of trkB Receptors in the Mossy Fiber Pathway of Adult Mouse Hippocampus

2002 • 79 citations

Amygdala kindling induces muscarinic cholinergic receptor declines in a highly specific distribution within the limbic system

1980 • 73 citations

Postnatal development of the light and electron microscopic features of basket cells in the hippocampal dentate gyrus of the rat

1990 • 62 citations

Dendritic development of dentate granule cells in the absence of their specific extrinsic afferents

1994 • 52 citations

Differentiation of dentate granule cells in slice cultures of rat hippocampus: a Golgi/electron microscopic study

1991 • 52 citations

Absence of hippocampal mossy fiber sprouting in transgenic mice overexpressing brain‐derived neurotrophic factor

2001 • 39 citations

Quantitative and morphological analysis of dentate granule cells with recurrent basal dendrites from normal and epileptic rats

2002 • 36 citations

Dentate granule cell layer collagen explant cultures: Spontaneous axonal growth and induction by brain-derived neurotrophic factor or basic fibroblast growth factor

1996 • 35 citations

Transient elevation in catalytic trkB mRNA during postnatal development of the rat brain.

1993 • 20 citations

Dentate granule cell layer collagen explant cultures: spontaneous axonal growth and induction by brain-derived neurotrophic factor or basic fibroblast growth factor

1996 • 2 citations

Absence of hippocampal mossy fiber sprouting in transgenic mice overexpressing brain‐derived neurotrophic factor

2001 • 2 citations