Intrinsic Voltage Dependence and Ca2+ Regulation of mslo Large Conductance Ca-activated K+ Channels

Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells.

1979 • 1,648 citations

Ionic Blockage of Sodium Channels in Nerve

1973 • 1,590 citations

Ionic Channels of Excitable Membranes, 2nd Ed.

1992 • 1,283 citations

Structural parts involved in activation and inactivation of the sodium channel

1989 • 1,189 citations

Calcium-activated potassium channels

1998 • 934 citations

Mutations in the K+ channel signature sequence

1994 • 828 citations

THE HEMOGLOBIN SYSTEM

1925 • 813 citations

Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.

1994 • 763 citations

Varieties of Calcium-Activated Potassium Channels

1989 • 731 citations

Properties of single calcium‐activated potassium channels in cultured rat muscle

1982 • 721 citations

Contribution of the S4 Segment to Gating Charge in the Shaker K+ Channel

1996 • 678 citations

Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel

1989 • 663 citations

Voltage-Sensing Residues in the S2 and S4 Segments of the Shaker K+ Channel

1996 • 654 citations

Ca-dependent K channels with large unitary conductance in chromaffin cell membranes

1981 • 647 citations

mSlo , a Complex Mouse Gene Encoding "Maxi" Calcium-Activated Potassium Channels

1993 • 638 citations

Mutations Affecting Internal TEA Blockade Identify the Probable Pore-Forming Region of a K ⁺ Channel

1991 • 634 citations

A Component of Calcium-activated Potassium Channels Encoded by the Drosophila slo Locus

1991 • 629 citations

Molecular Basis of Charge Movement in Voltage-Gated Sodium Channels

1996 • 603 citations

Negative surface charge near sodium channels of nerve: divalent ions, monovalent ions, and pH

1975 • 599 citations

Direct Physical Measure of Conformational Rearrangement Underlying Potassium Channel Gating

1996 • 598 citations

Mutations Affecting Tea Blockade and Ion Permeation in Voltage-activated K ⁺ Channels

1990 • 569 citations

Shaker potassium channel gating. III: Evaluation of kinetic models for activation.

1994 • 512 citations

Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence

1991 • 507 citations

Transmembrane Movement of the Shaker K+ Channel S4

1996 • 496 citations

Calcium-activated potassium channels expressed from cloned complementary DNAs

1992 • 488 citations

A Functional Connection Between the Pores of Distantly Related Ion Channels as Revealed by Mutant K ⁺ Channels

1992 • 479 citations

Functional role of the β subunit of high conductance calcium-activated potassium channels

1995 • 462 citations

Alteration of ionic selectivity of a K+ channel by mutation of the H5 region

1991 • 445 citations

Cloning, expression, and distribution of functionally distinct Ca2+-activated K+ channel isoforms from human brain

1994 • 425 citations

The Size of Gating Charge in Wild-Type and Mutant Shaker Potassium Channels

1992 • 422 citations

Single channel recordings of Ca2+-activated K+ currents in rat muscle cell culture

1981 • 408 citations

Voltage gating of ion channels

1994 • 405 citations

Evidence for voltage-dependent S4 movement in sodium channels

1995 • 396 citations

Faster superoxide dismutase mutants designed by enhancing electrostatic guidance

1992 • 387 citations

Gating kinetics of Ca2+-activated K+ channels from rat muscle incorporated into planar lipid bilayers. Evidence for two voltage-dependent Ca2+ binding reactions.

1983 • 379 citations

The effect of changing the internal solution on sodium inactivation and related phenomena in giant axons.

1965 • 345 citations

Kinetic analysis of voltage‐ and ion‐dependent conductances in saccular hair cells of the bull‐frog, Rana catesbeiana.

1988 • 305 citations

Reconstitution in planar lipid bilayers of a Ca2+-dependent K+ channel from transverse tubule membranes isolated from rabbit skeletal muscle.

1982 • 305 citations

Shaker potassium channel gating. II: Transitions in the activation pathway.

1994 • 299 citations

Drei Vorträge über Diffusion, Brownsche Molekularbewegung und Koagulation von Kolloidteilchen

1927 • 296 citations

Voltage-sensing residues in the S4 region of a mammalian K+ channel

1991 • 275 citations

Determinant for β-subunit regulation in high-conductance voltage-activated and Ca ²⁺ -sensitive K ⁺ channels: An additional transmembrane region at the N terminus

1996 • 272 citations

Calcium-activated potassium channels: Regulation by calcium

1991 • 263 citations

Calcium sensitivity of BK-type KCa channels determined by a separable domain

1994 • 240 citations

A model for electrical resonance and frequency tuning in saccular hair cells of the bull‐frog, Rana catesbeiana.

1988 • 238 citations

Kinetic states and modes of single large‐conductance calcium‐activated potassium channels in cultured rat skeletal muscle.

1988 • 226 citations

Characterization of and modulation by a beta-subunit of a human maxi KCa channel cloned from myometrium.

1995 • 183 citations

Tetraethylammonium block of Slowpoke calcium-activated potassium channels expressed in Xenopus oocytes: Evidence for tetrameric channel formation

1994 • 181 citations

Characterization of calcium-activated potassium channels in single smooth muscle cells using the patch-clamp technique

1987 • 178 citations

Functional differences among alternatively spliced variants of Slowpoke, a Drosophila calcium-activated potassium channel.

1994 • 175 citations

Single calcium-dependent potassium channels in clonal anterior pituitary cells

1982 • 173 citations

Gating kinetics of the cyclic-GMP-activated channel of retinal rods: flash photolysis and voltage-jump studies.

1988 • 169 citations

The physiological role of calcium-dependent channels

1989 • 164 citations

Accounting for the Ca(2+)‐dependent kinetics of single large‐conductance Ca(2+)‐activated K+ channels in rat skeletal muscle.

1991 • 160 citations

The gating of single calcium-dependent potassium channels is described by an activation/blockade mechanism

1982 • 155 citations

A human calcium-activated potassium channel gene expressed in vascular smooth muscle

1995 • 147 citations

Allosteric Effects of Mg2+ on the Gating of Ca2+-Activated K+ Channels From Mammalian Skeletal Muscle

1986 • 146 citations

Hydrophobic substitution mutations in the S4 sequence alter voltage-dependent gating in shaker K+ channels

1991 • 145 citations

High-conductance K+ channel in pancreatic islet cells can be activated and inactivated by internal calcium

1985 • 143 citations

The calcium-activated potassium channels of turtle hair cells.

1995 • 143 citations

Single channel activity associated with the calcium dependent outward current inHelix pomatia

1981 • 134 citations

S4 mutations alter gating currents of Shaker K channels

1994 • 132 citations

A kinetic description of the calcium-activated potassium channel and its application to electrical tuning of hair cells

1995 • 129 citations

Activation by divalent cations of a Ca2+-activated K+ channel from skeletal muscle membrane.

1988 • 122 citations

Interactions between intrinsic membrane protein and electric field. An approach to studying nerve excitability

1978 • 104 citations

THE HEMOGLOBIN SYSTEM

1925 • 96 citations

Inverse relationship of the durations of adjacent open and shut intervals for Cl and K channels

1985 • 96 citations

Developmental acquisition of Ca2+-sensitivity by K+ channels in spinal neurones

1985 • 75 citations

Distinct effects of Ca2+ and voltage on the activation and deactivation of cloned Ca(2+)‐activated K+ channels.

1995 • 75 citations

Separation of Gating Properties from Permeation and Block in mslo Large Conductance Ca-activated K+ Channels

1997 • 67 citations

A mouse brain homolog of the Drosophila Shab K+ channel with conserved delayed-rectifier properties

1991 • 66 citations

N-bromoacetamide removes a calcium-dependent component of channel opening from calcium-activated potassium channels in rat skeletal muscle.

1985 • 59 citations

Calcium‐activated potassium channels in rat muscle inactivate from a short‐duration open state.

1985 • 57 citations

Gating of maxi K+ channels studied by Ca2+ concentration jumps in excised inside-out multi-channel patches (myocytes from guinea pig urinary bladder).

1992 • 57 citations

Reconstitution of expressed KCa channels from Xenopus oocytes to lipid bilayers

1994 • 54 citations

Gating charge differences between two voltagegated K+ channels are due to the specific charge content of their respective S4 regions

1993 • 52 citations

Functional reconstitution of the large-conductance, calcium-activated potassium channel purified from bovine aortic smooth muscle

1995 • 50 citations

Interaction of internal Ba2+ with a cloned Ca(2+)-dependent K+ (hslo) channel from smooth muscle.

1996 • 48 citations

Occult Drosophila Calcium Channels and Twinning of Calcium and Voltage-Activated Potassium Channels

1986 • 38 citations

A Ba2+ chelator suppresses long shut events in fully activated high-conductance Ca(2+)-dependent K+ channels

1996 • 30 citations

Modification of Ca2+-activated K+ channels in cultured medullary thick ascending limb cells by N-bromoacetamide

1987 • 25 citations

Effect of trypsin on a Ca(2+)-activated K+ channel reconstituted into planar phospholipid bilayers

1992 • 16 citations

Single channel recordings from calcium-activated potassium channels in cultured rat muscle

1983 • 8 citations

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