The CaaX motif of lamin A functions in conjunction with the nuclear localization signal to target assembly to the nuclear envelope

Current protocols in molecular biology

1988 • 7,584 citations

All ras proteins are polyisoprenylated but only some are palmitoylated

1989 • 1,806 citations

Sequence requirements for nuclear location of simian virus 40 large-T antigen

1984 • 1,278 citations

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

1986 • 1,100 citations

The nuclear envelope lamina is reversibly depolymerized during mitosis

1980 • 956 citations

Oligonucleotide-Directed Mutagenesis: A Simple Method Using Two Oligonucleotide Primers and a Single-Stranded DNA Template

1984 • 947 citations

Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins

1986 • 836 citations

Tropomyosin coiled-coil interactions: Evidence for an unstaggered structure

1975 • 670 citations

Functional Organization Of The Nuclear Envelope

1988 • 593 citations

The p21 ras C-terminus is required for transformation and membrane association

1984 • 590 citations

Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen

1984 • 566 citations

Post-translational processing of p21ras is two-step and involves carboxyl-methylation and carboxy-terminal proteolysis.

1989 • 462 citations

Antibodies to the Golgi complex and the rough endoplasmic reticulum.

1982 • 418 citations

Harvey murine sarcoma virus p21 ras protein: biological and biochemical significance of the cysteine nearest the carboxy terminus.

1984 • 403 citations

Posttranslational modification of the Ha-ras oncogene protein: evidence for a third class of protein carboxyl methyltransferases.

1988 • 384 citations

A cell free system to study reassembly of the nuclear envelope at the end of mitosis

1986 • 382 citations

Structure of Saccharomyces cerevisiae mating hormone a-factor. Identification of S-farnesyl cysteine as a structural component.

1988 • 373 citations

A lamin B receptor in the nuclear envelope.

1988 • 370 citations

Phosphorylation of the nuclear lamins during interphase and mitosis.

1985 • 354 citations

THE NUCLEUS: STRUCTURE, FUNCTION, AND DYNAMICS

1987 • 333 citations

RAM, a gene of yeast required for a functional modification of RAS proteins and for production of mating pheromone a-factor

1986 • 259 citations

Evidence for modification of lamin B by a product of mevalonic acid.

1988 • 254 citations

Mutations in the nuclear lamin proteins resulting in their aberrant assembly in the cytoplasm.

1988 • 217 citations

The dynamic nature of the Golgi complex.

1989 • 210 citations

Incorporation of a product of mevalonic acid metabolism into proteins of Chinese hamster ovary cell nuclei.

1988 • 181 citations

Comparative biochemical properties of p21 ras molecules coded for by viral and cellular ras genes

1982 • 179 citations

Nuclear lamin LI of Xenopus laevis: cDNA cloning, amino acid sequence and binding specificity of a member of the lamin B subfamily.

1987 • 141 citations

The conserved carboxy-terminal cysteine of nuclear lamins is essential for lamin association with the nuclear envelope.

1989 • 134 citations

Autoimmune response directed against conserved determinants of nuclear envelope proteins in a patient with linear scleroderma.

1983 • 133 citations

Drosophila nuclear lamin precursor Dm0 is translated from either of two developmentally regulated mRNA species apparently encoded by a single gene [published erratum appears in J Cell Biol 1988 Jun;106(6):2225]

1988 • 130 citations

Amino acid sequence and molecular characterization of murine lamin B as deduced from cDNA clones.

1988 • 127 citations

Two-codon insertion mutagenesis of plasmid genes by using single-stranded hexameric oligonucleotides.

1985 • 126 citations

Processing and fatty acid acylation of RAS1 and RAS2 proteins in Saccharomyces cerevisiae.

1986 • 108 citations

A new lamin in Xenopus somatic tissues displays strong homology to human lamin A.

1987 • 106 citations

Coiled coil formation and sequence regularities in the helical regions of α-keratin

1978 • 79 citations

Posttranslational modification of ras proteins: Detection of a modification prior to fatty acid acylation and cloning of a gene responsible for the modification

1988 • 41 citations

Nuclear lamin proteins: common structures for paracrystalline, filamentous and lattice forms

1987 • 36 citations

Viral glycoproteins at different stages of intracellular transport can be distinguished using monoclonal antibodies.

1983 • 17 citations