Quantification and localization of PEGylated polycyanoacrylate nanoparticles in brain and spinal cord during experimental allergic encephalomyelitis in the rat

Nanocapsule formation by interfacial polymer deposition following solvent displacement

1989 • 2,090 citations

Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy.

1991 • 1,591 citations

Long circulating microparticulate drug carriers

1995 • 699 citations

Brain drug delivery of small molecules using immunoliposomes

1996 • 640 citations

Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis

1997 • 534 citations

Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles)

1995 • 528 citations

Significant transport of doxorubicin into the brain with polysorbate 80-coated nanoparticles.

1999 • 516 citations

Lower limits of cerebrovascular permeability to nonelectrolytes in the conscious rat

1978 • 444 citations

Long-circulating PEGylated polycyanoacrylate nanoparticles as new drug carrier for brain delivery.

2001 • 437 citations

Stealth® PEGylated polycyanoacrylate nanoparticles for intravenous administration and splenic targeting

1999 • 388 citations

Delivery of loperamide across the blood-brain barrier with polysorbate 80-coated polybutylcyanoacrylate nanoparticles.

1997 • 353 citations

Bone marrow derived elements and resident microglia in brain inflammation

1993 • 352 citations

Tumoral Distribution of Long-circulating Dextran-coated Iron Oxide Nanoparticles in a Rodent Model

2000 • 349 citations

Pharmacokinetics and distribution of a biodegradable drug-carrier

1983 • 312 citations

The Blood-brain Barrier: Principles for Targeting Peptides and Drugs to the Central Nervous System

1996 • 283 citations

Quantitative aspects of reversible osmotic opening of the blood-brain barrier

1980 • 276 citations

Degradation of poly (isobutyl cyanoacrylate) nanoparticles

1984 • 266 citations

Coating particles with a block co-polymer (poloxamine-908) suppresses opsonization but permits the activity of dysopsonins in the serum

1993 • 252 citations

Improved delineation of human brain tumors on MR images using a long-circulating, superparamagnetic iron oxide agent

1999 • 239 citations

Doxorubicin encapsulated in sterically stabilized liposomes for the treatment of a brain tumor model: biodistribution and therapeutic efficacy

1995 • 229 citations

Adsorption of Antineoplastic Drugs to Polyalkylcyanoacrylate Nanoparticles and Their Release in Calf Serum

1979 • 181 citations

Blood‐Brain Barrier in Physiology and Medicine

1977 • 166 citations

The effect of hydrophilic coatings on the uptake of colloidal particles by the liver and by peritoneal macrophages

1986 • 152 citations

Nanoparticles, a drug carrier system to pass the blood-brain barrier, permit central analgesic effects of i.v. dalargin injections

1996 • 141 citations

Pegylated nanoparticles from a novel methoxypolyethylene glycol cyanoacrylate-hexadecyl cyanoacrylate amphiphilic copolymer.

1998 • 134 citations

Quantitative study of microvessel ultrastructure in human peritumoral brain tissue

1987 • 107 citations

Increased vesicular transport and decreased mitochondrial content in blood-brain barrier endothelial cells during experimental autoimmune encephalomyelitis.

1989 • 85 citations

Synthesis of a Novel Poly(MePEG cyanoacrylate-co-alkyl cyanoacrylate) Amphiphilic Copolymer for Nanoparticle Technology

1997 • 80 citations

Mechanisms regulating body distribution of nanospheres conditioned with pluronic and tetronic block co-polymers

1995 • 73 citations

Neoplastic and pharmacological influence on the permeability of an in vitro blood-brain barrier

1995 • 56 citations

Near infrared with principal component analysis as a novel analytical approach for nanoparticle technology.

2000 • 51 citations

Early detection of liposome brain localization in rat experimental allergic encephalomyelitis

1999 • 33 citations

MAGNETIC RESONANCE IMAGING OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS IN PRIMATES

1991 • 27 citations

Pathophysiological aspects of acute experimental allergic encephalomyelitis

1988 • 26 citations

Relation between the increase in the diffusional permeability of the blood-central nervous system barrier and other changes during the development of experimental allergic encephalomyelitis in the lewis rat

1983 • 24 citations

Concordance and localization of maximal vascular permeability change and fibrin deposition in the central neuraxis of Lewis rats with cell-transferred experimental allergic encephalomyelitis

1992 • 20 citations

Systemic enzymatic changes in guinea pigs suffering from experimental allergic encephalomyelitis.

1983 • 11 citations